1W1W
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![BU of 1w1w by Molmil](/molmil-images/mine/1w1w) | Sc Smc1hd:Scc1-C complex, ATPgS | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SISTER CHROMATID COHESION PROTEIN 1, ... | Authors: | Haering, C, Nasmyth, K, Lowe, J. | Deposit date: | 2004-06-24 | Release date: | 2004-09-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and stability of cohesin's Smc1-kleisin interaction. Mol. Cell, 15, 2004
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1W4B
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![BU of 1w4b by Molmil](/molmil-images/mine/1w4b) | P4 protein from PHI12 in complex with product (AMPcPP Mg 22C) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NTPASE P4 | Authors: | Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I. | Deposit date: | 2004-07-22 | Release date: | 2004-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation Cell(Cambridge,Mass.), 118, 2004
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1W96
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![BU of 1w96 by Molmil](/molmil-images/mine/1w96) | Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A | Descriptor: | ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A | Authors: | Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. | Deposit date: | 2004-10-06 | Release date: | 2005-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
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1WAV
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![BU of 1wav by Molmil](/molmil-images/mine/1wav) | CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN | Descriptor: | INSULIN, PHENOL, ZINC ION | Authors: | Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L. | Deposit date: | 1996-02-28 | Release date: | 1997-02-28 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular replacement study on form-B monoclinic crystal of insulin. Sci.China, Ser.C: Life Sci., 39, 1996
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1W8L
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![BU of 1w8l by Molmil](/molmil-images/mine/1w8l) | |
1W9B
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![BU of 1w9b by Molmil](/molmil-images/mine/1w9b) | S. alba myrosinase in complex with carba-glucotropaeolin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBA-GLUCOTROPAEOLIN, ... | Authors: | Bourderioux, A, Lefoix, M, Gueyrard, D, Tatibouet, A, Cottaz, S, Arzt, S, Burmeister, W.P, Rollin, P. | Deposit date: | 2004-10-08 | Release date: | 2005-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The glucosinolate-myrosinase system. New insights into enzyme-substrate interactions by use of simplified inhibitors. Org. Biomol. Chem., 3, 2005
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1W13
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![BU of 1w13 by Molmil](/molmil-images/mine/1w13) | UROKINASE TYPE PLASMINOGEN ACTIVATOR | Descriptor: | N-(BENZYLSULFONYL)-D-SERYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BENZYL)-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | Authors: | Jacob, U. | Deposit date: | 2004-06-15 | Release date: | 2008-05-20 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors. J.Mol.Biol., 328, 2003
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1W79
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![BU of 1w79 by Molmil](/molmil-images/mine/1w79) | Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39 | Descriptor: | D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION | Authors: | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | Deposit date: | 2004-08-31 | Release date: | 2005-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins. J. Biol. Chem., 280, 2005
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1W3G
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![BU of 1w3g by Molmil](/molmil-images/mine/1w3g) | Hemolytic lectin from the mushroom Laetiporus sulphureus complexed with two N-acetyllactosamine molecules. | Descriptor: | GLYCEROL, HEMOLYTIC LECTIN FROM LAETIPORUS SULPHUREUS, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Mancheno, J.M, Tateno, H, Goldstein, I.J, Martinez-Ripoll, M, Hermoso, J.A. | Deposit date: | 2004-07-15 | Release date: | 2005-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural Analysis of the Laetiporus Sulphureus Hemolytic Pore-Forming Lectin in Complex with Sugars J.Biol.Chem., 280, 2005
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1WAK
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![BU of 1wak by Molmil](/molmil-images/mine/1wak) | X-ray structure of SRPK1 | Descriptor: | 1,2-ETHANEDIOL, SERINE/THREONINE-PROTEIN KINASE SPRK1 | Authors: | Ngo, J.C, Gullingsrud, J, Chakrabarti, S, Nolen, B, Aubol, B.E, Fu, X.D, Adams, J.A, Mccammon, J.A, Ghosh, G. | Deposit date: | 2004-10-26 | Release date: | 2006-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Sr Protein Kinase 1 is Resilient to Inactivation. Structure, 15, 2007
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1W1B
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1W4L
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![BU of 1w4l by Molmil](/molmil-images/mine/1w4l) | Complex of TcAChE with bis-acting galanthamine derivative | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Greenblatt, H.M, Guillou, C, Guenard, D, Badet, B, Thal, C, Silman, I, Sussman, J.L. | Deposit date: | 2004-07-25 | Release date: | 2004-11-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J.Am.Chem.Soc., 126, 2004
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1W36
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![BU of 1w36 by Molmil](/molmil-images/mine/1w36) | RecBCD:DNA complex | Descriptor: | CALCIUM ION, DNA HAIRPIN, EXODEOXYRIBONUCLEASE V ALPHA CHAIN, ... | Authors: | Singleton, M.R, Dillingham, M.S, Gaudier, M, C Kowalczykowski, S, Wigley, D.B. | Deposit date: | 2004-07-13 | Release date: | 2004-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of Recbcd Enzyme Reveals a Machine for Processing DNA Breaks Nature, 432, 2004
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1W6R
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![BU of 1w6r by Molmil](/molmil-images/mine/1w6r) | Complex of TcAChE with galanthamine derivative | Descriptor: | (-)-GALANTHAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Greenblatt, H.M, Guillou, C, Guenard, D, Badet, B, Thal, C, Silman, I, Sussman, J.L. | Deposit date: | 2004-08-23 | Release date: | 2004-11-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J.Am.Chem.Soc., 126, 2004
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1W46
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![BU of 1w46 by Molmil](/molmil-images/mine/1w46) | P4 protein from Bacteriophage PHI12 in complex with ADP and MG | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NTPASE P4 | Authors: | Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I. | Deposit date: | 2004-07-22 | Release date: | 2004-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation Cell(Cambridge,Mass.), 118, 2004
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1W9C
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![BU of 1w9c by Molmil](/molmil-images/mine/1w9c) | Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats | Descriptor: | CRM1 PROTEIN | Authors: | Petosa, C, Schoehn, G, Askjaer, P, Bauer, U, Moulin, M, Steuerwald, U, Soler-Lopez, M, Baudin, F, Mattaj, I.W, Muller, C.W. | Deposit date: | 2004-10-08 | Release date: | 2004-12-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Architecture of Crm1-Exportin 1 Suggests How Cooperativity is Achieved During Formation of a Nuclear Export Complex Mol.Cell, 16, 2004
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1W4Q
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![BU of 1w4q by Molmil](/molmil-images/mine/1w4q) | Binding of Nonnatural 3'-Nucleotides to Ribonuclease A | Descriptor: | 2'-FLUORO-2'-DEOXYURIDINE 3'-MONOPHOSPHATE, PANCREATIC RIBONUCLEASE A | Authors: | Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T. | Deposit date: | 2004-07-27 | Release date: | 2005-02-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Binding of Non-Natural 3'-Nucleotides to Ribonuclease A FEBS J., 272, 2005
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1WAO
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![BU of 1wao by Molmil](/molmil-images/mine/1wao) | PP5 structure | Descriptor: | MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5 | Authors: | Barford, D. | Deposit date: | 2004-10-27 | Release date: | 2005-02-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5 Embo J., 24, 2005
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1W97
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![BU of 1w97 by Molmil](/molmil-images/mine/1w97) | cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae | Descriptor: | TYPE II SECRETION SYSTEM PROTEIN L | Authors: | Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J. | Deposit date: | 2004-10-06 | Release date: | 2004-11-30 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily J.Mol.Biol., 344, 2004
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1W9D
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![BU of 1w9d by Molmil](/molmil-images/mine/1w9d) | S. alba myrosinase in complex with S-ethyl phenylacetothiohydroximate- O-sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Bourderioux, A, Lefoix, M, Gueyrard, D, Tatibouet, A, Cottaz, S, Arzt, S, Burmeister, W.P, Rollin, P. | Deposit date: | 2004-10-08 | Release date: | 2005-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Glucosinolate-Myrosinase System. New Insights Into Enzyme-Substrate Interactions by Use of Simplified Inhibitors Org.Biomol.Chem., 3, 2005
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1W7H
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![BU of 1w7h by Molmil](/molmil-images/mine/1w7h) | p38 Kinase crystal structure in complex with small molecule inhibitor | Descriptor: | 3-(BENZYLOXY)PYRIDIN-2-AMINE, MITOGEN-ACTIVATED PROTEIN KINASE 14 | Authors: | Jhoti, H, Gill, A, Cleasby, A, Devine, L. | Deposit date: | 2004-09-02 | Release date: | 2005-02-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.214 Å) | Cite: | Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48, 2005
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1W9V
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![BU of 1w9v by Molmil](/molmil-images/mine/1w9v) | Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus | Descriptor: | ARGIFIN, CHITINASE, SULFATE ION | Authors: | Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F. | Deposit date: | 2004-10-19 | Release date: | 2005-01-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12, 2005
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1W5Y
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![BU of 1w5y by Molmil](/molmil-images/mine/1w5y) | HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor | Descriptor: | (2R,3R,4R,5R)-2,5-BIS[(2,5-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE, POL POLYPROTEIN | Authors: | Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. | Deposit date: | 2004-08-10 | Release date: | 2004-10-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem., 271, 2004
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1WBK
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![BU of 1wbk by Molmil](/molmil-images/mine/1wbk) | |
1WB8
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![BU of 1wb8 by Molmil](/molmil-images/mine/1wb8) | Iron Superoxide Dismutase (FE-SOD) from the Hyperthermophile SULFOLOBUS SOLFATARICUS. 2.3 A Resolution Structure of Recombinant Protein with a Covalently Modified Tyrosine in the Active Site. | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE [FE], phenylmethanesulfonic acid | Authors: | Ursby, T, Adinolfi, B.S, Al-Karadaghi, S, De Vendittis, E, Bocchini, V. | Deposit date: | 2004-10-31 | Release date: | 2004-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Iron Superoxide Dismutase from the Archaeon Sulfolobus Solfataricus: Analysis of Structure and Thermostability J.Mol.Biol., 286, 1999
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