PDB: 55698 resultsInfo pagesStatus searchChemie searchBIRD

---

1OWD	Substituted 2-Naphthamidine inhibitors of urokinase Descriptor: 6-[AMINO(IMINO)METHYL]-N-[(4R)-4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL]-2-NAPHTHAMIDE, Urokinase-type plasminogen activator Authors: Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. Deposit date: 2003-03-28 Release date: 2003-09-30 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
2J78	Beta-glucosidase from Thermotoga maritima in complex with gluco- hydroximolactam Descriptor: (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 1,2-ETHANEDIOL, ACETATE ION, ... Authors: Gloster, T.M, Zechel, D, Vasella, A, Davies, G.J. Deposit date: 2006-10-06 Release date: 2006-10-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics. J.Am.Chem.Soc., 129, 2007
4I5U	Crystal structure of a fungal chimeric cellobiohydrolase Cel6A Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ... Authors: Arnold, F.H, Wu, I. Deposit date: 2012-11-29 Release date: 2013-04-03 Last modified: 2017-08-09 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures. Biotechnol.Bioeng., 110, 2013
4MPZ	Crystal structure of TCP10c domain of Drosophila melanogaster Sas-4 Descriptor: IMIDAZOLE, Sas-4 Authors: Li, H, Zheng, X. Deposit date: 2013-09-14 Release date: 2014-01-01 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.701 Å) Cite: The conserved TCP domain of Sas-4/CPAP is essential for Peri-centriolar material tethering during centrosome biogenesis Proc.Natl.Acad.Sci.USA, 2014
4MQB	Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TETRAETHYLENE GLYCOL, Thymidylate kinase Authors: Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Jedrzejczak, R, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) Deposit date: 2013-09-16 Release date: 2013-10-23 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid To be Published
4E84	Crystal Structure of Burkholderia cenocepacia HldA Descriptor: 1,7-di-O-phosphono-D-glycero-beta-D-manno-heptopyranose, 7-O-phosphono-D-glycero-beta-D-manno-heptopyranose, CHLORIDE ION, ... Authors: Lee, T.-W, Junop, M.S. Deposit date: 2012-03-19 Release date: 2012-12-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural-functional studies of Burkholderia cenocepacia D-glycero-beta-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties. J.Med.Chem., 56, 2013
4LHT	Crystal Structure of P450cin Y81F mutant, crystallized in 3 mM 1,8-cineole Descriptor: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Madrona, Y, Poulos, T.L. Deposit date: 2013-07-01 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.137 Å) Cite: P450cin active site water: implications for substrate binding and solvent accessibility. Biochemistry, 52, 2013
4L77	P450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility Descriptor: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, DI(HYDROXYETHYL)ETHER, P450cin, ... Authors: Madrona, Y, Poulos, T.L. Deposit date: 2013-06-13 Release date: 2013-07-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.379 Å) Cite: P450cin active site water: implications for substrate binding and solvent accessibility. Biochemistry, 52, 2013
4EDV	The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese Descriptor: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ... Authors: Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. Deposit date: 2012-03-27 Release date: 2012-07-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
4EE7	Crystal Structure of the Novel Phenazine Prenyltransferase EpzP in complex with S-thiolodiphosphate (methylated) Descriptor: CHLORIDE ION, Prenyltransferase, SULFATE ION, ... Authors: Zocher, G, Stehle, T. Deposit date: 2012-03-28 Release date: 2012-11-14 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase. Plos One, 7, 2012
4I3Y	Crystal structure of Staphylococcal inositol monophosphatase-1: 100 mM LiCl soaked inhibitory complex Descriptor: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... Authors: Dutta, A, Bhattacharyya, S, Dutta, D, Das, A.K. Deposit date: 2012-11-26 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural elucidation of the binding site and mode of inhibition of Li(+) and Mg(2+) in inositol monophosphatase. Febs J., 281, 2014
3EF0	The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase Descriptor: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAFLUOROALUMINATE ION Authors: Ghosh, A, Lima, C.D. Deposit date: 2008-09-07 Release date: 2008-12-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol.Cell, 32, 2008
4I5R	Crystal structure of a fungal chimeric cellobiohydrolase Cel6A Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ... Authors: Arnold, F.H, Wu, I. Deposit date: 2012-11-28 Release date: 2013-04-03 Last modified: 2017-08-09 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures. Biotechnol.Bioeng., 110, 2013
3WA3	Crystal structure of copper amine oxidase from arthrobacter globiformis in N2 condition Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... Authors: Murakawa, T, Hayashi, H, Sunami, T, Kurihara, K, Tamada, T, Kuroki, R, Suzuki, M, Tanizawa, K, Okajima, T. Deposit date: 2013-04-22 Release date: 2013-09-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis: assignment of bound diatomic molecules as O2 Acta Crystallogr.,Sect.D, 69, 2013
3EMJ	2.2 A crystal structure of inorganic pyrophosphatase from rickettsia prowazekii (p21 form) Descriptor: Inorganic pyrophosphatase, TETRAETHYLENE GLYCOL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2008-09-24 Release date: 2008-10-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: 2.2 A crystal structure of inorganic pyrophosphatase from rickettsia prowazekii (p21 form) To be Published
4LD1	Structural analysis of the microcephaly protein CPAP G-box domain suggests a role in centriole elongation. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NITRATE ION, TETRAETHYLENE GLYCOL, ... Authors: Hatzopoulos, G.N, Vakonakis, I. Deposit date: 2013-06-24 Release date: 2013-09-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure, 21, 2013
3EI3	Structure of the hsDDB1-drDDB2 complex Descriptor: DNA damage-binding protein 1, DNA damage-binding protein 2, TETRAETHYLENE GLYCOL Authors: Scrima, A, Thoma, N.H. Deposit date: 2008-09-15 Release date: 2009-01-20 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
3EJN	CRYSTAL STRUCTURE OF A SUSD HOMOLOG (BF3025) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 1.50 A RESOLUTION Descriptor: FORMIC ACID, MAGNESIUM ION, SusD homolog, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-09-18 Release date: 2008-09-30 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of SusD homolog (YP_212639.1) from Bacteroides fragilis NCTC 9343 at 1.50 A resolution To be published
3EN8	Crystal structure of NTF-2 like protein of unknown function (YP_553245.1) from BURKHOLDERIA XENOVORANS LB400 at 1.85 A resolution Descriptor: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-09-25 Release date: 2008-10-07 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of NTF-2 like protein of unknown function (YP_553245.1) from BURKHOLDERIA XENOVORANS LB400 at 1.85 A resolution To be published
2IEH	Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF11, ... Authors: Garcia-Saez, I, Kozielski, F. Deposit date: 2006-09-19 Release date: 2007-01-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration. J.Biol.Chem., 282, 2007
3WA2	High resolution crystal structure of copper amine oxidase from arthrobacter globiformis Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... Authors: Murakawa, T, Hayashi, H, Sunami, T, Kurihara, K, Tamada, T, Kuroki, R, Suzuki, M, Tanizawa, K, Okajima, T. Deposit date: 2013-04-22 Release date: 2013-09-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.08 Å) Cite: High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis: assignment of bound diatomic molecules as O2 Acta Crystallogr.,Sect.D, 69, 2013
1C3W	BACTERIORHODOPSIN/LIPID COMPLEX AT 1.55 A RESOLUTION Descriptor: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, 2,10,23-TRIMETHYL-TETRACOSANE, BACTERIORHODOPSIN (GROUND STATE WILD TYPE "BR"), ... Authors: Luecke, H. Deposit date: 1999-07-28 Release date: 1999-09-15 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of bacteriorhodopsin at 1.55 A resolution. J.Mol.Biol., 291, 1999
1OWK	Substituted 2-Naphthamidine Inhibitors of Urokinase Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-(1-ISOPROPYL-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)-2-NAPHTHAMIDE, Urokinase-type plasminogen activator Authors: Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. Deposit date: 2003-03-28 Release date: 2003-09-30 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
4LGQ	Crystal structure of a putative polyketide cyclase (CV_0247) from Chromobacterium violaceum ATCC 12472 at 2.72 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2013-06-28 Release date: 2013-07-24 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Crystal structure of a putative polyketide cyclase (CV_0247) from Chromobacterium violaceum ATCC 12472 at 2.72 A resolution To be published
3ET4	Structure of Recombinant Haemophilus Influenzae E(P4) Acid Phosphatase Descriptor: MAGNESIUM ION, Outer membrane protein P4, NADP phosphatase, ... Authors: Tanner, J.J. Deposit date: 2008-10-06 Release date: 2008-10-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of Recombinant Haemophilus Influenzae E (P4) Acid Phosphatase Reveals a New Member of the Haloacid Dehalogenase Superfamily. Biochemistry, 46, 2007

<503504505506507508509510511512513514515516517518>