4HF8
 
 | | Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with glycine | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCINE, Methionine gamma-lyase, ... | | Authors: | Revtovich, S.V, Morozova, E.A, Anufrieva, N.V, Nikulin, A.D, Demidkina, T.V. | | Deposit date: | 2012-10-05 | | Release date: | 2013-11-06 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the external aldimine of Citrobacter freundii methionine gamma-lyase with glycine provides insight in mechanisms of two stages of physiological reaction and isotope exchange of alpha- and beta-protons of competitive inhibitors.
Biochimie, 101, 2014
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6LXU
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4ITX
 | | P113S mutant of E. coli Cystathionine beta-lyase MetC inhibited by reaction with L-Ala-P | | Descriptor: | CALCIUM ION, Cystathionine beta-lyase MetC, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID | | Authors: | Squire, C.J, Yosaatmadja, Y, Soo, V.W.C, Patrick, W.M. | | Deposit date: | 2013-01-19 | | Release date: | 2014-12-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.
J.Biol.Chem., 291, 2016
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4IXS
 | | Native structure of xometc at ph 5.2 | | Descriptor: | CARBONATE ION, Cystathionine gamma-lyase-like protein, GLYCEROL | | Authors: | Ngo, H.P.T, Kim, J.K, Kang, L.W. | | Deposit date: | 2013-01-28 | | Release date: | 2014-01-29 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | PLP undergoes conformational changes during the course of an enzymatic reaction.
Acta Crystallogr.,Sect.D, 70, 2014
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4IY7
 | | crystal structure of cystathionine gamma lyase (XometC) from Xanthomonas oryzae pv. oryzae in complex with E-site serine, A-site external aldimine structure with serine and A-site external aldimine structure with aminoacrylate intermediates | | Descriptor: | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Cystathionine gamma-lyase-like protein, ... | | Authors: | Ngo, H.P.T, Kim, J.K, Kang, L.W. | | Deposit date: | 2013-01-28 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | PLP undergoes conformational changes during the course of an enzymatic reaction.
Acta Crystallogr.,Sect.D, 70, 2014
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5X2V
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5X2Y
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5X2W
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5X2Z
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5X2X
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4IXZ
 | | Native structure of cystathionine gamma lyase (XometC) from xanthomonas oryzae pv. oryzae at pH 9.0 | | Descriptor: | BETA-MERCAPTOETHANOL, BICARBONATE ION, Cystathionine gamma-lyase-like protein, ... | | Authors: | Ngo, H.P.T, Kim, J.K, Kang, L.W. | | Deposit date: | 2013-01-28 | | Release date: | 2014-01-29 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | PLP undergoes conformational changes during the course of an enzymatic reaction.
Acta Crystallogr.,Sect.D, 70, 2014
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4IYO
 | | Crystal structure of cystathionine gamma lyase from Xanthomonas oryzae pv. oryzae (XometC) in complex with E-site serine, A-site serine, A-site external aldimine structure with aminoacrylate and A-site iminopropionate intermediates | | Descriptor: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, AMINO-ACRYLATE, Cystathionine gamma-lyase-like protein, ... | | Authors: | Ngo, H.P.T, Kim, J.K, Kang, L.W. | | Deposit date: | 2013-01-29 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | PLP undergoes conformational changes during the course of an enzymatic reaction.
Acta Crystallogr.,Sect.D, 70, 2014
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3AEN
 | | Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate | | Descriptor: | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, GLYCEROL, METHIONINE, ... | | Authors: | Karaki, T, Sato, D, Shimizu, A, Nozaki, T, Harada, S. | | Deposit date: | 2010-02-10 | | Release date: | 2011-02-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of Entamoeba histolytica methionine gamma-lyase 1
To be Published
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4ITG
 | | P113S mutant of E. coli Cystathionine beta-lyase MetC | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cystathionine beta-lyase MetC | | Authors: | Squire, C.J, Yosaatmadja, Y, Soo, V.W.C, Patrick, W.M. | | Deposit date: | 2013-01-18 | | Release date: | 2014-12-24 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.
J.Biol.Chem., 291, 2016
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3AEL
 | | Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing methionine imine-pyridoxamine-5'-phosphate and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate | | Descriptor: | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-4-(methylsulfanyl)butanoic acid, (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, GLYCEROL, ... | | Authors: | Karaki, T, Sato, D, Shimizu, A, Nozaki, T, Harada, S. | | Deposit date: | 2010-02-10 | | Release date: | 2011-02-09 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of Entamoeba histolytica methionine gamma-lyase 1
To be Published
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3AEJ
 | | Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 tetramer containing Michaelis complex and methionine-pyridoxal-5'-phosphate | | Descriptor: | GLYCEROL, METHIONINE, Methionine gamma-lyase, ... | | Authors: | Karaki, T, Sato, D, Shimizu, A, Nozaki, T, Harada, S. | | Deposit date: | 2010-02-10 | | Release date: | 2011-02-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of Entamoeba histolytica methionine gamma-lyase 1
To be Published
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1GC2
 | | CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA | | Descriptor: | METHIONINE GAMMA-LYASE | | Authors: | Motoshima, H, Inagaki, K, Kumasaka, T, Furuichi, M, Inoue, H, Tamura, T, Esaki, N, Soda, K, Tanaka, N, Yamamoto, M, Tanaka, H. | | Deposit date: | 2000-07-06 | | Release date: | 2002-05-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
J.Biochem., 128, 2000
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1GC0
 | | CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA | | Descriptor: | METHIONINE GAMMA-LYASE | | Authors: | Motoshima, H, Inagaki, K, Kumasaka, T, Furuichi, M, Inoue, H, Tamura, T, Esaki, N, Soda, K, Tanaka, N, Yamamoto, M, Tanaka, H. | | Deposit date: | 2000-07-06 | | Release date: | 2002-05-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
J.Biochem., 128, 2000
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1E5E
 | | METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE | | Descriptor: | GLYCEROL, METHIONINE GAMMA-LYASE, N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE, ... | | Authors: | Goodall, G, Mottram, J.C, Coombs, G.H, Lapthorn, A.J. | | Deposit date: | 2000-07-25 | | Release date: | 2001-07-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | The Structure and Proposed Catalytic Mechanism of Methionine Gamma-Lyase
To be Published
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1E5F
 | | METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS | | Descriptor: | GLYCEROL, METHIONINE GAMMA-LYASE, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Goodall, G, Mottram, J.C, Coombs, G.H, Lapthorn, A.J. | | Deposit date: | 2000-07-25 | | Release date: | 2001-07-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | The Structure and Proposed Catalytic Mechanism of Methionine Gamma-Lyase
To be Published
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1IBJ
 | | Crystal structure of cystathionine beta-lyase from Arabidopsis thaliana | | Descriptor: | CARBONATE ION, CYSTATHIONINE BETA-LYASE, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Breitinger, U, Clausen, T, Messerschmidt, A. | | Deposit date: | 2001-03-28 | | Release date: | 2001-04-04 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity
Plant Physiol., 126, 2001
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1I43
 | | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA | | Descriptor: | 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | | Deposit date: | 2001-02-19 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
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1I41
 | | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA | | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID, CYSTATHIONINE GAMMA-SYNTHASE | | Authors: | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | | Deposit date: | 2001-02-19 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
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1I48
 | | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO | | Descriptor: | CARBOXYMETHYLTHIO-3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOL, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | | Deposit date: | 2001-02-20 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
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8SA7
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