7Z4C
| SpCas9 bound to 6 nucleotide complementary DNA substrate | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 6 nucleotide complementary DNA substrate, Target strand of 6 nucleotide complementary DNA substrate, ... | Authors: | Pacesa, M, Jinek, M. | Deposit date: | 2022-03-03 | Release date: | 2022-08-31 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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7Z4H
| SpCas9 bound to 14-nucleotide complementary DNA substrate | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 14-nucleotide complementary DNA substrate, Target strand of 14-nucleotide complementary DNA substrate, ... | Authors: | Pacesa, M, Jinek, M. | Deposit date: | 2022-03-03 | Release date: | 2022-08-31 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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7Z4G
| SpCas9 bound to 12-nucleotide complementary DNA substrate | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 12-nucleotide complementary DNA substrate, Target strand of 12-nucleotide complementary DNA substrate, ... | Authors: | Pacesa, M, Jinek, M. | Deposit date: | 2022-03-03 | Release date: | 2022-08-31 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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7Z4K
| SpCas9 bound to 10-nucleotide complementary DNA substrate | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10-nucleotide complementary DNA substrate, Target strand of 10-nucleotide complementary DNA substrate, ... | Authors: | Pacesa, M, Jinek, M. | Deposit date: | 2022-03-04 | Release date: | 2022-08-31 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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7Z4L
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2RSI
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6B40
| BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry | Descriptor: | 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ... | Authors: | Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G. | Deposit date: | 2017-09-25 | Release date: | 2019-03-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Transposon molecular domestication and the evolution of the RAG recombinase. Nature, 569, 2019
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436D
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6EVU
| Adhesin domain of PrgB from Enterococcus faecalis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, PrgB | Authors: | Schmitt, A, Berntsson, R.P.A. | Deposit date: | 2017-11-02 | Release date: | 2018-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.598 Å) | Cite: | PrgB promotes aggregation, biofilm formation, and conjugation through DNA binding and compaction. Mol. Microbiol., 109, 2018
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7E29
| Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, J, Smolle, M, Liang, H, Liu, Y. | Deposit date: | 2021-02-05 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function. Nucleic Acids Res., 50, 2022
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1U7B
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7F45
| Structure of an Anti-CRISPR protein | Descriptor: | AcrIF5 | Authors: | Feng, Y. | Deposit date: | 2021-06-17 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition. Nat.Chem.Biol., 18, 2022
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5D5K
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2WBT
| The Structure of a Double C2H2 Zinc Finger Protein from a Hyperthermophilic Archaeal Virus in the Absence of DNA | Descriptor: | B-129, ZINC ION | Authors: | Eilers, B.J, Menon, S, Windham, A.B, Kraft, P, Dlakic, M, Young, M.J, Lawrence, C.M. | Deposit date: | 2009-03-03 | Release date: | 2010-03-31 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of a Double C2H2 Zinc Finger Protein from a Hyperthermophilic Archaeal Virus in the Absence of DNA To be Published
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1JMS
| Crystal Structure of the Catalytic Core of Murine Terminal Deoxynucleotidyl Transferase | Descriptor: | MAGNESIUM ION, SODIUM ION, TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE | Authors: | Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Sukumar, N, Jourdan, N, Rougeon, F, Papanicolaou, C. | Deposit date: | 2001-07-19 | Release date: | 2002-01-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. Embo J., 21, 2002
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7CLG
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3KIO
| mouse RNase H2 complex | Descriptor: | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C | Authors: | Shaban, N, Harvey, S, Perrino, F.W, Hollis, T. | Deposit date: | 2009-11-02 | Release date: | 2009-11-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. J.Biol.Chem., 285, 2010
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3ZEH
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1HSM
| THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA | Descriptor: | BETA-MERCAPTOETHANOL, HIGH MOBILITY GROUP PROTEIN 1 | Authors: | Read, C.M, Cary, P.D, Crane-Robinson, C, Driscoll, P.C, Carillo, M.O.M, Norman, D.G. | Deposit date: | 1994-11-17 | Release date: | 1995-02-07 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The Structure of the Hmg Box and its Interaction with DNA To be Published
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2RQP
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1PFE
| Echinomycin-(gcgtacgc)2 complex | Descriptor: | 2-CARBOXYQUINOXALINE, 5'-D(*GP*CP*GP*TP*AP*CP*GP*C)-3', CHLORIDE ION, ... | Authors: | Cuesta-Seijo, J.A. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structures of Complexes between Echinomycin and Duplex DNA. Acta Crystallogr.,Sect.D, 61, 2005
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1XI1
| Phi29 DNA polymerase ssDNA complex, monoclinic crystal form | Descriptor: | 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION | Authors: | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | Deposit date: | 2004-09-21 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Correction of X-ray intensities from single crystals containing lattice-translocation defects Acta Crystallogr.,Sect.D, 61, 2005
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3IJK
| 5-OMe modified DNA 8mer | Descriptor: | 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3' | Authors: | Sheng, J, Zhang, W, Hassan, A.E.A, Gan, J, Huang, Z. | Deposit date: | 2009-08-04 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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2MT3
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2BEJ
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