PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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2M24	NMR solution structure of the d3'-hairpin including the exon binding site 1 (EBS1) of the group II intron Sc.ai5gamma Descriptor: RNA (29-MER) Authors: Kruschel, D, Skilandat, M, Sigel, R.K.O. Deposit date: 2012-12-12 Release date: 2013-12-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition. Rna, 20, 2014
6KLH	Dimeric structure of Machupo virus polymerase bound to vRNA promoter Descriptor: MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... Authors: Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. Deposit date: 2019-07-30 Release date: 2020-03-18 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insight into arenavirus replication machinery. Nature, 579, 2020
6KLC	Structure of apo Lassa virus polymerase Descriptor: MANGANESE (II) ION, RNA-directed RNA polymerase L Authors: Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. Deposit date: 2019-07-30 Release date: 2020-03-18 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insight into arenavirus replication machinery. Nature, 579, 2020
6KLD	Structure of apo Machupo virus polymerase Descriptor: MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION Authors: Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. Deposit date: 2019-07-30 Release date: 2020-03-18 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Structural insight into arenavirus replication machinery. Nature, 579, 2020
4AWK	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 1 Descriptor: (2Z)-4-[(3S)-1-(benzylsulfonyl)-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA Authors: Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. Deposit date: 2012-06-04 Release date: 2012-08-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
3MF5	Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor Descriptor: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase Authors: Harris, S.F, Tavares, G, Ghate, M. Deposit date: 2010-04-01 Release date: 2010-07-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
5ZX2	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA Descriptor: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
5I13	Endonuclease inhibitor 2 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0 Descriptor: 4-{(E)-[2-(4-chlorophenyl)hydrazinylidene]methyl}benzene-1,2,3-triol, MANGANESE (II) ION, Polymerase acidic protein, ... Authors: Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Hoshino, T. Deposit date: 2016-02-05 Release date: 2016-02-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55, 2016
2BPC	CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM Descriptor: DNA POLYMERASE BETA, MANGANESE (II) ION Authors: Sawaya, M.R, Pelletier, H, Kumar, A, Wilson, S.H, Kraut, J. Deposit date: 1994-07-08 Release date: 1994-08-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science, 264, 1994
8YFQ	Cryo EM structure of Komagataella phaffii RNAPII-Rat1-Rai1 pre-termination complex Descriptor: 5'-3' exoribonuclease, DNA (90-mer), DNA-directed RNA polymerase subunit, ... Authors: Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. Deposit date: 2024-02-25 Release date: 2024-09-25 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
7O7Z	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O81	Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O80	Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O7Y	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
8YFR	Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex bound within the RNAPII cleft Descriptor: 5'-3' exoribonuclease, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. Deposit date: 2024-02-25 Release date: 2024-09-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
6Z6N	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
5ZYP	Structure of the Yeast Ctr9/Paf1 complex Descriptor: NICKEL (II) ION, RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1 Authors: Xie, Y, Zheng, M, Zhou, H, Long, J. Deposit date: 2018-05-28 Release date: 2018-09-26 Last modified: 2019-05-22 Method: X-RAY DIFFRACTION (2.532 Å) Cite: Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation. Nat Commun, 9, 2018
7QGG	Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Pulk, A, Kipper, K, Mansour, A. Deposit date: 2021-12-08 Release date: 2022-10-26 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state. J.Mol.Biol., 434, 2022
5FZ5	Transcription initiation complex structures elucidate DNA opening (CC) Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. Deposit date: 2016-03-10 Release date: 2016-05-18 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (8.8 Å) Cite: Transcription Initiation Complex Structures Elucidate DNA Opening Nature, 533, 2016
5FYW	Transcription initiation complex structures elucidate DNA opening (OC) Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. Deposit date: 2016-03-10 Release date: 2016-05-18 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.35 Å) Cite: Transcription Initiation Complex Structures Elucidate DNA Opening Nature, 533, 2016
8P4B	Structural insights into human co-transcriptional capping - structure 2 Descriptor: DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
6Z6L	Cryo-EM structure of human CCDC124 bound to 80S ribosomes Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
8P4E	Structural insights into human co-transcriptional capping - structure 5 Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (26-MER), DNA (35-MER), ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-07-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4D	Structural insights into human co-transcriptional capping - structure 4 Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023

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