Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4WTE
DownloadVisualize
BU of 4wte by Molmil
CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-ACAAAUUU
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Edwards, T.E, Appleby, T.C.
Deposit date:2014-10-29
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for RNA replication by the hepatitis C virus polymerase.
Science, 347, 2015
4WTG
DownloadVisualize
BU of 4wtg by Molmil
CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH SOFOSBUVIR DIPHOSPHATE GS-607596, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU
Descriptor: 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Edwards, T.E, Appleby, T.C.
Deposit date:2014-10-30
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for RNA replication by the hepatitis C virus polymerase.
Science, 347, 2015
5C0W
DownloadVisualize
BU of 5c0w by Molmil
Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Makino, D.L, Conti, E.
Deposit date:2015-06-12
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
6KUR
DownloadVisualize
BU of 6kur by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUK
DownloadVisualize
BU of 6kuk by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUP
DownloadVisualize
BU of 6kup by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUV
DownloadVisualize
BU of 6kuv by Molmil
Structure of influenza D virus polymerase bound to cRNA promoter in class 2
Descriptor: 3'-cRNA, 5'-cRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUT
DownloadVisualize
BU of 6kut by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
1MWH
DownloadVisualize
BU of 1mwh by Molmil
REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MANGANESE (II) ION, MINOR CORE PROTEIN LAMBDA 3
Authors:Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
Deposit date:2002-09-29
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3
Cell(Cambridge,Mass.), 111, 2002
5C0X
DownloadVisualize
BU of 5c0x by Molmil
Structure of a 12-subunit nuclear exosome complex bound to structured RNA
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Makino, D.L, Conti, E.
Deposit date:2015-06-12
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
8HPP
DownloadVisualize
BU of 8hpp by Molmil
Crystal structure of human INTS3 with SAGE1
Descriptor: Integrator complex subunit 3, Sarcoma antigen 1
Authors:Deng, W, Wu, J, Lei, M.
Deposit date:2022-12-12
Release date:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II
To Be Published
9GUR
DownloadVisualize
BU of 9gur by Molmil
30S mRNA delivery complex TEC resolved (TEC only)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Rahil, H, Weixlbaumer, A, Webster, M.W.
Deposit date:2024-09-20
Release date:2024-11-20
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular basis of mRNA delivery to the bacterial ribosome.
Science, 386, 2024
2HHP
DownloadVisualize
BU of 2hhp by Molmil
Structure of yeast poly(A) polymerase in a closed conformation.
Descriptor: CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase
Authors:Bohm, A, Toth, J.
Deposit date:2006-06-28
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
6TW1
DownloadVisualize
BU of 6tw1 by Molmil
Bat Influenza A polymerase termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence
Descriptor: 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2020-01-11
Release date:2020-04-15
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 2020
6XJF
DownloadVisualize
BU of 6xjf by Molmil
X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha (SeMet labeled protein)
Descriptor: Transcription factor E
Authors:Murakami, K.S, Jun, S.H.
Deposit date:2020-06-23
Release date:2020-07-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
6RFG
DownloadVisualize
BU of 6rfg by Molmil
Structure of the Vaccinia core protein E11
Descriptor: 15 kDa core protein
Authors:Grimm, C, Fischer, U.
Deposit date:2019-04-15
Release date:2019-12-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Cell, 179, 2019
8YQY
DownloadVisualize
BU of 8yqy by Molmil
ASFV RNA polymerase-M1249L complex complete
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
8YQU
DownloadVisualize
BU of 8yqu by Molmil
African swine fever virus RNA Polymerase-M1249L complex1
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
8YQT
DownloadVisualize
BU of 8yqt by Molmil
African swine fever virus RNA Polymerase-M1249L complex2
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
8YQZ
DownloadVisualize
BU of 8yqz by Molmil
African swine fever virus RNA Polymerase--DNA complex
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
8YQW
DownloadVisualize
BU of 8yqw by Molmil
ASFV RNA polymerase-M1249L complex3
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
1N38
DownloadVisualize
BU of 1n38 by Molmil
reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed
Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ...
Authors:Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
Deposit date:2002-10-25
Release date:2002-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
8YQV
DownloadVisualize
BU of 8yqv by Molmil
African swine fever virus RNA Polymerase core
Descriptor: C122R, C147L, D339L, ...
Authors:Feng, X.Y.
Deposit date:2024-03-20
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Transcription regulation of African swine fever virus: dual role of M1249L.
Nat Commun, 15, 2024
1N1H
DownloadVisualize
BU of 1n1h by Molmil
Initiation complex of polymerase lambda3 from reovirus
Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ...
Authors:Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
Deposit date:2002-10-17
Release date:2002-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
6UU3
DownloadVisualize
BU of 6uu3 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (4.002 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020

238582

数据于2025-07-09公开中

PDB statisticsPDBj update infoContact PDBjnumon