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7TBF	Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-61.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... Authors: Zhou, T, Tsybovsky, T, Kwong, P.D. Deposit date: 2021-12-21 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7TE1	SARS-CoV-2 Receptor Binding Domain in Complex with Ab17 Descriptor: Ab17 heavy chain, Ab17 light chain, Spike protein S1 Authors: Hauser, B.M, Schmidt, A.G. Deposit date: 2022-01-03 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep, 38, 2022
7TB8	Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhou, T, Tsybovsky, T, Kwong, P.D. Deposit date: 2021-12-21 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7TF3	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) Q484A spike protein Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. Deposit date: 2022-01-06 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (2.25 Å) Cite: Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7TF1	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) Q484I spike protein (focused refinement of RBD) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. Deposit date: 2022-01-06 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7TF5	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. Deposit date: 2022-01-06 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7TC9	Locally refined region of SARS-CoV-2 spike in complex with antibody A19-46.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, Light chain of antibody A19-46.1, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-23 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (5.08 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7TF4	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein (focused refinement of RBD) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. Deposit date: 2022-01-06 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7T01	SARS-CoV-2 S-RBD + Fab 54042-4 Descriptor: 54042-4 Fab - Heavy Chain, 54042-4 Fab - Light Chain, Spike protein S1 Authors: Johnson, N.V, Mclellan, J.S. Deposit date: 2021-11-29 Release date: 2022-04-13 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep, 37, 2021
7SWO	C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) Descriptor: C98C7 Fab heavy chain, C98C7 Fab light chain, Spike protein S1 Authors: Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. Deposit date: 2021-11-20 Release date: 2022-04-27 Last modified: 2022-11-09 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
7SWP	G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) Descriptor: G32Q4 Fab heavy chain, G32Q4 Fab light chain, Spike protein S1 Authors: Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. Deposit date: 2021-11-20 Release date: 2022-04-27 Last modified: 2022-11-09 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
7SWN	G32A4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) Descriptor: G32A4 Fab heavy chain, G32A4 Fab light chain, Spike protein S1 Authors: Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. Deposit date: 2021-11-20 Release date: 2022-04-27 Last modified: 2022-11-09 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
7T67	SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Byrne, P.O, McLellan, J.S. Deposit date: 2021-12-13 Release date: 2022-08-24 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (3 Å) Cite: IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nat Commun, 13, 2022
7T3M	SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ... Authors: Byrne, P.O, McLellan, J.S. Deposit date: 2021-12-08 Release date: 2022-08-24 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nat Commun, 13, 2022
7TCQ	Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, DI(HYDROXYETHYL)ETHER, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-28 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability. Structure, 30, 2022
7T7B	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ... Authors: Liu, H, Wilson, I.A. Deposit date: 2021-12-14 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Commun Biol, 5, 2022
7SWW	SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ... Authors: Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2021-11-21 Release date: 2022-11-23 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published
7SWX	SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ... Authors: Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2021-11-21 Release date: 2022-11-23 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published
7T72	Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... Authors: Langley, D.B, Christ, D, Rouet, R. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.177 Å) Cite: Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients. Nat Commun, 14, 2023
7TOU	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; consensus state D1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7TOV	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; consensus state D2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7TOX	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D5 state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7TOY	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D6 state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7TOZ	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D7 state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7TP0	Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D8 state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Gobeil, S, Acharya, P. Deposit date: 2022-01-24 Release date: 2022-02-09 Last modified: 2023-04-12 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

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