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1COH
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BU of 1coh by Molmil
STRUCTURE OF HAEMOGLOBIN IN THE DEOXY QUATERNARY STATE WITH LIGAND BOUND AT THE ALPHA HAEMS
Descriptor: CARBON MONOXIDE, HEMOGLOBIN (COBALTOUS DEOXY) (BETA CHAIN), HEMOGLOBIN (FERROUS CARBONMONOXY) (ALPHA CHAIN), ...
Authors:Luisi, B.
Deposit date:1989-01-13
Release date:1990-01-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of haemoglobin in the deoxy quaternary state with ligand bound at the alpha haems.
J.Mol.Biol., 206, 1989
5UNP
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BU of 5unp by Molmil
Structure of CDC2-Like Kinase 2 (CLK2) in Complex with Compound T-025 [N2-methyl-N4-(pyrimidin-2-ylmethyl)-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine]
Descriptor: Dual specificity protein kinase CLK2, N~2~-methyl-N~4~-[(pyrimidin-2-yl)methyl]-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Authors:Klein, M.G, Tjhen, R.
Deposit date:2017-01-31
Release date:2018-05-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:A novel CLK inhibitor exhibits anti-tumor efficacies via modulating pre-mRNA splicing and targeting a MYC-dependent vulnerability
Embo Mol Med, 2018
5KVM
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BU of 5kvm by Molmil
Extracellular region of mouse GPR56/ADGRG1 in complex with FN3 monobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G-protein coupled receptor G1, ...
Authors:Salzman, G.S, Ding, C, Koide, S, Arac, D.
Deposit date:2016-07-14
Release date:2016-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.449 Å)
Cite:Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.
Neuron, 91, 2016
6DC5
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BU of 6dc5 by Molmil
RSV prefusion F in complex with AM22 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Jones, H.G, McLellan, J.S.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6GX7
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BU of 6gx7 by Molmil
Tubulin-CopN-alphaRep complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2018-06-26
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
3N6S
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BU of 3n6s by Molmil
Crystal structure of human mitochondrial mTERF in complex with a 15-mer DNA encompassing the tRNALeu(UUR) binding sequence
Descriptor: DNA (5'-D(*AP*TP*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*A)-3'), Transcription termination factor, ...
Authors:Jimenez-Menendez, N, Fernandez-Millan, P, Rubio-Cosials, A, Arnan, C, Montoya, J, Jacobs, H.T, Bernado, P, Coll, M, Uson, I, Sola, M.
Deposit date:2010-05-26
Release date:2010-06-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.
Nat.Struct.Mol.Biol., 17, 2010
3N7Q
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BU of 3n7q by Molmil
Crystal structure of human mitochondrial mTERF fragment (aa 99-399) in complex with a 12-mer DNA encompassing the tRNALeu(UUR) binding sequence
Descriptor: CITRIC ACID, DNA (5'-D(*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*G)-3'), ...
Authors:Jimenez-Menendez, N, Fernandez-Millan, P, Rubio-Cosials, A, Arnan, C, Montoya, J, Jacobs, H.T, Bernado, P, Coll, M, Uson, I, Sola, M.
Deposit date:2010-05-27
Release date:2010-06-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.
Nat.Struct.Mol.Biol., 17, 2010
3ERR
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BU of 3err by Molmil
Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase
Descriptor: ADENOSINE MONOPHOSPHATE, fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus
Authors:Carter, A.P.
Deposit date:2008-10-03
Release date:2008-11-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structure and functional role of dynein's microtubule-binding domain.
Science, 322, 2008
5LT0
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BU of 5lt0 by Molmil
nucleotide-free kinesin-1 motor domain, P212121 crystal form
Descriptor: ACETATE ION, Kinesin-like protein, STRONTIUM ION, ...
Authors:Cao, L, Gigant, B.
Deposit date:2016-09-06
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5LO8
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BU of 5lo8 by Molmil
The C2B domain of Rabphilin 3A in complex with PI(4,5)P2
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2016-08-08
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LT4
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BU of 5lt4 by Molmil
nucleotide-free kinesin-1 motor domain T92V mutant, P1 crystal form
Descriptor: Kinesin-1 heavy chain, SULFATE ION
Authors:Cao, L, Gigant, B.
Deposit date:2016-09-06
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.881 Å)
Cite:The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5MF1
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BU of 5mf1 by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the Chlamydomonas reinhardtii gamete fusion protein HAP2
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein HAP2/GCS1
Authors:Fedry, J, Rey, F.A, Krey, T.
Deposit date:2016-11-17
Release date:2017-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein.
Cell, 168, 2017
5LT3
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BU of 5lt3 by Molmil
nucleotide-free kinesin-1 motor domain T87A mutant, P1 crystal form
Descriptor: Kinesin-1 heavy chain, SULFATE ION
Authors:Cao, L, Gigant, B.
Deposit date:2016-09-06
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5LT2
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BU of 5lt2 by Molmil
nucleotide-free kinesin-1 motor domain, P1 crystal form
Descriptor: Kinesin-like protein, SULFATE ION
Authors:Cao, L, Gigant, B.
Deposit date:2016-09-06
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5LT1
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BU of 5lt1 by Molmil
nucleotide-free kinesin-1 motor domain T92V mutant, P21 crystal form
Descriptor: ACETATE ION, Kinesin-like protein, STRONTIUM ION, ...
Authors:Cao, L, Gigant, B.
Deposit date:2016-09-06
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
6TGG
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BU of 6tgg by Molmil
scFv-1SM3 in complex with glycopeptide containing an sp2-imino sugar
Descriptor: 1,2-ETHANEDIOL, Mucin-1, ScFv_SM3, ...
Authors:Bermejo, I.A, Navo, C.D, Castro-Lopez, J, Samchez-Fernandez, E.M, Guerreiro, A, Avenoza, A, Busto, J.H, Garcia-Martin, F, Nishimura, S.I, Garcia-Fernandez, J.M, Ortiz-Mellet, C, Bernardes, G.J.L, Hurtado-Guerrero, R, Peregrina, J.M, Corzana, F.
Deposit date:2019-11-15
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp 2 -iminosugar fragment.
Chem Sci, 11, 2020
2OKO
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BU of 2oko by Molmil
Z. mobilis tRNA guanine transglycosylase E235Q mutant apo-structure at pH 5.5
Descriptor: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Tidten, N.
Deposit date:2007-01-17
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies.
J.Mol.Biol., 374, 2007
6QBZ
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BU of 6qbz by Molmil
Solution structure of the N-terminal domain of the Staphylococcus aureus Hibernation Promoting Factor
Descriptor: Ribosome hibernation promoting factor
Authors:Usachev, K.S, Validov, S.Z, Khusainov, I.S, Klochkov, V.V, Aganov, A.V, Yusupov, M.M.
Deposit date:2018-12-25
Release date:2019-06-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal domain of the Staphylococcus aureus hibernation promoting factor.
J.Biomol.Nmr, 73, 2019
1RCQ
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BU of 1rcq by Molmil
The 1.45 A crystal structure of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms
Descriptor: D-LYSINE, PYRIDOXAL-5'-PHOSPHATE, catabolic alanine racemase DadX
Authors:Le Magueres, P, Im, H, Dvorak, A, Strych, U, Benedik, M, Krause, K.L.
Deposit date:2003-11-04
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms.
Biochemistry, 42, 2003
5LOB
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BU of 5lob by Molmil
Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2016-08-09
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOW
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BU of 5low by Molmil
Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1P9P
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BU of 1p9p by Molmil
The Crystal Structure of a M1G37 tRNA Methyltransferase, TrmD
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase
Authors:Elkins, P.A, Watts, J.M, Zalacain, M, Van Thiel, A, Vitaszka, P.R, Redlak, M, Andraos-Selim, C, Rastinejad, F, Holmes, W.M.
Deposit date:2003-05-12
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
J.Mol.Biol., 333, 2003
2QII
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BU of 2qii by Molmil
Crystal Structure Of tRNA-Guanine Transglycosylase (TGT) From Zymomonas mobilis Complexed With Archaeosine Precursor, Preq0
Descriptor: 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
Authors:Tidten, N, Brenk, R, Heine, A, Reuter, K, Klebe, G.
Deposit date:2007-07-04
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies.
J.Mol.Biol., 374, 2007
6MLJ
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BU of 6mlj by Molmil
Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S70A mutant from Salmonella typhimurium complexed with arginine
Descriptor: ACETATE ION, ARGININE, Lysine/arginine/ornithine transport protein
Authors:Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A.
Deposit date:2018-09-27
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020
6MLV
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BU of 6mlv by Molmil
Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) Y14A mutant from Salmonella typhimurium
Descriptor: Lysine/arginine/ornithine-binding periplasmic protein
Authors:Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A.
Deposit date:2018-09-28
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.082 Å)
Cite:The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020

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