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3IYB
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BU of 3iyb by Molmil
Poliovirus early RNA-release intermediate
Descriptor: Genome polyprotein, Precursor polyprotein, VP1 core
Authors:Levy, H.C, Bostina, M, Filman, D.J, Hogle, J.M.
Deposit date:2009-07-21
Release date:2010-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
J.Virol., 84, 2010
7K5L
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BU of 7k5l by Molmil
Ebola virus VP40 octameric ring generated by an RNA oligonucleotide
Descriptor: HSP RNA oligonucleotide, Matrix protein VP40
Authors:Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O.
Deposit date:2020-09-17
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
6E80
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BU of 6e80 by Molmil
Crystal structure of the Corn aptamer in unliganded state
Descriptor: ACETATE ION, IRIDIUM HEXAMMINE ION, IRIDIUM ION, ...
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2018-07-27
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Cell Chem Biol, 26, 2019
8JYH
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BU of 8jyh by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid C
Descriptor: 7-[5-[(2~{S})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid, MANGANESE (II) ION, Pol protein,Pol protein,HIV-1 Reverse Transcriptase RNase H active domain, ...
Authors:Ito, Y, Lu, H, Kitajima, M, Ishikawa, H, Nakata, Y, Iwatani, Y, Hoshino, T.
Deposit date:2023-07-03
Release date:2023-08-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase.
J.Nat.Prod., 86, 2023
8JYJ
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BU of 8jyj by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid A
Descriptor: 7-[5-(2-acetamidoethyl)-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid, MANGANESE (II) ION, Pol protein,Pol protein,HIV-1 Reverse Transcriptase RNase H active domain, ...
Authors:Ito, Y, Lu, H, Kitajima, M, Ishikawa, H, Nakata, Y, Iwatani, Y, Hoshino, T.
Deposit date:2023-07-03
Release date:2023-08-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase.
J.Nat.Prod., 86, 2023
2JLF
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BU of 2jlf by Molmil
STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M.
Deposit date:2008-09-08
Release date:2008-11-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
2JLG
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BU of 2jlg by Molmil
STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE
Descriptor: 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M.
Deposit date:2008-09-09
Release date:2008-11-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
5NKO
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BU of 5nko by Molmil
Solution structure of the C-terminal domain of S. aureus Hibernating Promoting Factor (CTD-SaHPF)
Descriptor: Ribosome hibernation promotion factor
Authors:Usachev, K.S, Khusainov, I.S, Ayupov, R.K, Validov, S.Z, Kieffer, B, Yusupov, M.M.
Deposit date:2017-03-31
Release date:2017-07-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
3CJ4
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BU of 3cj4 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Antonysamy, s.s.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2PXQ
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BU of 2pxq by Molmil
Variant 14 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXK
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BU of 2pxk by Molmil
Variant 8 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXD
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BU of 2pxd by Molmil
Variant 1 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXP
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BU of 2pxp by Molmil
Variant 13 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXE
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BU of 2pxe by Molmil
Variant 4 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXV
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BU of 2pxv by Molmil
Variant 6 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXT
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BU of 2pxt by Molmil
Variant 15 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXU
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BU of 2pxu by Molmil
Variant 16 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXF
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BU of 2pxf by Molmil
Variant 5 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2PXB
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BU of 2pxb by Molmil
Variant 2 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
1DM9
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BU of 1dm9 by Molmil
HEAT SHOCK PROTEIN 15 KD
Descriptor: HYPOTHETICAL 15.5 KD PROTEIN IN MRCA-PCKA INTERGENIC REGION, SULFATE ION
Authors:Staker, B.L, Korber, P, Bardwell, J.C.A, Saper, M.A.
Deposit date:1999-12-14
Release date:2000-02-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Hsp15 reveals a novel RNA-binding motif.
EMBO J., 19, 2000
2PXL
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BU of 2pxl by Molmil
Variant 9 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle
Descriptor: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein
Authors:Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S.
Deposit date:2007-05-14
Release date:2007-08-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A General Strategy to Solve the Phase Problem in RNA Crystallography.
Structure, 15, 2007
2KX8
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BU of 2kx8 by Molmil
NMR structure of stem-loop 4 from the human 7SK snRNA in complex with arginine
Descriptor: 7SK, ARGININE
Authors:Durney, M.A, D'Souza, V.M.
Deposit date:2010-04-27
Release date:2010-09-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Preformed protein-binding motifs in 7SK snRNA: structural and thermodynamic comparisons with retroviral TAR.
J.Mol.Biol., 404, 2010
2A6E
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BU of 2a6e by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
4AUK
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BU of 4auk by Molmil
Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M.
Deposit date:2012-05-18
Release date:2012-08-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna.
Nucleic Acids Res., 40, 2012
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008

223790

数据于2024-08-14公开中

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