6NJE
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![BU of 6nje by Molmil](/molmil-images/mine/6nje) | Crystal structure of the motor domain of human kinesin family member 22 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF22, ... | Authors: | Walker, B.C, Zhu, H, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Park, H, Cochran, J.C, Structural Genomics Consortium (SGC) | Deposit date: | 2019-01-03 | Release date: | 2019-01-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the motor domain of human kinesin family member 22 To Be Published
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5HBN
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6N3J
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3HKP
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![BU of 3hkp by Molmil](/molmil-images/mine/3hkp) | Crystal structure determination of Catechol 1,2-Dioxygenase from Rhodococcus opacus 1CP in complex with protocatechuate | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 3,4-DIHYDROXYBENZOIC ACID, Catechol 1,2-dioxygenase, ... | Authors: | Matera, I, Ferraroni, M, Kolomytseva, M, Briganti, F, Scozzafava, A. | Deposit date: | 2009-05-25 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: Quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts. J.Struct.Biol., 170, 2010
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5KMW
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![BU of 5kmw by Molmil](/molmil-images/mine/5kmw) | TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex | Descriptor: | Beta-lactamase Toho-1, OPEN FORM - PENICILLIN G, PENICILLIN G, ... | Authors: | Coates, L, Langan, P.S, Vandavasi, V.G, Weiss, K.L, Cooper, J.B, Ginell, S.L. | Deposit date: | 2016-06-27 | Release date: | 2017-03-01 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex to be published
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2POQ
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![BU of 2poq by Molmil](/molmil-images/mine/2poq) | Dimeric Dihydrodiol Dehydrogenase complexed with inhibitor, Isoascorbic acid | Descriptor: | BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, ISOASCORBIC ACID, ... | Authors: | Carbone, V, El-Kabbani, O. | Deposit date: | 2007-04-27 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid. Acta Crystallogr.,Sect.D, 64, 2008
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2PJ1
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![BU of 2pj1 by Molmil](/molmil-images/mine/2pj1) | CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B (3-Aminomethyl-phenyl)-[((R)-1-benzyloxycarbonylamino-2-methyl-propyl)-hydroxy-phosphinoyloxy]-acetic acid COMPLEX | Descriptor: | (5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE, Carboxypeptidase B, ZINC ION | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2007-04-15 | Release date: | 2008-01-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64, 2008
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5FPO
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![BU of 5fpo by Molmil](/molmil-images/mine/5fpo) | Structure of Bacterial DNA Ligase with small-molecule ligand 1H- indazol-7-amine (AT4213) in an alternate binding site. | Descriptor: | 1H-indazol-7-amine, DNA LIGASE | Authors: | Jhoti, H, Ludlow, R.F, Pathuri, P, Saini, H.K, Tickle, I.J, Tisi, D, Verdonk, M, Williams, P.A. | Deposit date: | 2015-12-02 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
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5FPY
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![BU of 5fpy by Molmil](/molmil-images/mine/5fpy) | Structure of hepatitis C virus (HCV) full-length NS3 complex with small-molecule ligand 5-bromo-1-methyl-1H-indole-2-carboxylic acid (AT21457) in an alternate binding site. | Descriptor: | 5-bromo-1-methyl-1H-indole-2-carboxylic acid, SERINE PROTEASE NS3 | Authors: | Davies, T.G, Jhoti, H, Ludlow, R.F, Saini, H.K, Tickle, I.J, Verdonk, M. | Deposit date: | 2015-12-03 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
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5FPD
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![BU of 5fpd by Molmil](/molmil-images/mine/5fpd) | Structure of heat shock-related 70kDA protein 2 with small-molecule ligand pyrazine-2-carboxamide (AT513) in an alternate binding site. | Descriptor: | HEAT SHOCK-RELATED 70KDA PROTEIN 2, PYRAZINE-2-CARBOXAMIDE | Authors: | Jhoti, H, Ludlow, R.F, Patel, S, Saini, H.K, Tickle, I.J, Verdonk, M. | Deposit date: | 2015-11-28 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
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4PYT
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![BU of 4pyt by Molmil](/molmil-images/mine/4pyt) | Crystal structure of a MurB family EP-UDP-N-acetylglucosamine reductase | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | Authors: | Cao, H, Franz, L, Sen, S, Bingman, C.A, Auldridge, M, Steinmetz, E, Mead, D, Phillips Jr, G.N. | Deposit date: | 2014-03-27 | Release date: | 2014-05-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.853 Å) | Cite: | LucY: A Versatile New Fluorescent Reporter Protein. Plos One, 10, 2015
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3CDN
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![BU of 3cdn by Molmil](/molmil-images/mine/3cdn) | Crystal structure of a pheromone binding protein from Apis mellifera soaked at pH 4.0 | Descriptor: | CHLORIDE ION, GLYCEROL, Pheromone-binding protein ASP1 | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-02-27 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of the honey bee PBP pheromone and pH-induced conformational change J.Mol.Biol., 380, 2008
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5E29
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![BU of 5e29 by Molmil](/molmil-images/mine/5e29) | Crystal Structure of Deoxygenated Hemoglobin in Complex with an Allosteric Effector and Nitric Oxide | Descriptor: | 2-(nitrooxy)ethyl 2-(4-{2-[(3,5-dimethylphenyl)amino]-2-oxoethyl}phenoxy)-2-methylpropanoate, 2-{4-[(3,5-DIMETHYLANILINO)-CARBONYL-METHYL]-PHENOXY}-2-METHYLPROPIONIC ACID, CACODYLATE ION, ... | Authors: | Safo, M.K, Deshpande, T.M. | Deposit date: | 2015-09-30 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry. Biochemistry, 54, 2015
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6MYA
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5LAB
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3J0L
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![BU of 3j0l by Molmil](/molmil-images/mine/3j0l) | Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 9.8A cryo-EM map: classic PRE state 1 | Descriptor: | 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10, ... | Authors: | Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M. | Deposit date: | 2011-10-04 | Release date: | 2011-11-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Structure and dynamics of the Mammalian ribosomal pretranslocation complex. Mol.Cell, 44, 2011
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5HNT
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![BU of 5hnt by Molmil](/molmil-images/mine/5hnt) | Crystal Structure of AKR1C3 complexed with CAPE | Descriptor: | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, C, Zhao, Y, Zhang, H, Hu, X. | Deposit date: | 2016-01-18 | Release date: | 2017-03-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of AKR1C3 complexed with octyl gallate To Be Published
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3IHM
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5HNU
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![BU of 5hnu by Molmil](/molmil-images/mine/5hnu) | Crystal Structure of AKR1C3 complexed with octyl gallate | Descriptor: | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, octyl 3,4,5-trihydroxybenzoate | Authors: | Li, C, Zhao, Y, Zhang, H, Hu, X. | Deposit date: | 2016-01-18 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of AKR1C3 complexed with octyl gallte To Be Published
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5HWT
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![BU of 5hwt by Molmil](/molmil-images/mine/5hwt) | Crystal structure of apo-PAS1 | Descriptor: | Sensor histidine kinase TodS | Authors: | Hwang, J, Koh, S. | Deposit date: | 2016-01-29 | Release date: | 2016-03-02 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System. J. Biol. Chem., 291, 2016
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5CHR
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![BU of 5chr by Molmil](/molmil-images/mine/5chr) | Dehaloperoxidase B in complex with substrate p-nitrocatechol | Descriptor: | 4-NITROCATECHOL, Dehaloperoxidase B, GLYCEROL, ... | Authors: | Carey, L, Ghiladi, R. | Deposit date: | 2015-07-10 | Release date: | 2016-04-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Nonmicrobial Nitrophenol Degradation via Peroxygenase Activity of Dehaloperoxidase-Hemoglobin from Amphitrite ornata. Biochemistry, 55, 2016
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2OM3
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![BU of 2om3 by Molmil](/molmil-images/mine/2om3) | High-resolution cryo-EM structure of Tobacco Mosaic Virus | Descriptor: | Coat protein, Tobacco Mosaic Virus RNA | Authors: | Sachse, C. | Deposit date: | 2007-01-20 | Release date: | 2007-10-16 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus. J.Mol.Biol., 371, 2007
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5CHQ
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![BU of 5chq by Molmil](/molmil-images/mine/5chq) | Dehaloperoxidase B in complex with substrate p-nitrophenol | Descriptor: | Dehaloperoxidase B, GLYCEROL, P-NITROPHENOL, ... | Authors: | Carey, L, Ghiladi, R. | Deposit date: | 2015-07-10 | Release date: | 2016-04-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Nonmicrobial Nitrophenol Degradation via Peroxygenase Activity of Dehaloperoxidase-Hemoglobin from Amphitrite ornata. Biochemistry, 55, 2016
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2OU0
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2PJA
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![BU of 2pja by Molmil](/molmil-images/mine/2pja) | |