Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6TTE
DownloadVisualize
BU of 6tte by Molmil
Beta-galactosidase in complex with PETG
Descriptor: 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION
Authors:Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
Deposit date:2019-12-27
Release date:2020-01-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6SD0
DownloadVisualize
BU of 6sd0 by Molmil
Structure of beta-galactosidase from Thermotoga maritima.
Descriptor: Beta-galactosidase, MAGNESIUM ION
Authors:Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J.
Deposit date:2019-07-26
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering.
Acs Chem.Biol., 15, 2020
6TSH
DownloadVisualize
BU of 6tsh by Molmil
Beta-galactosidase in complex with deoxygalacto-nojirimycin
Descriptor: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION
Authors:Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
Deposit date:2019-12-20
Release date:2020-01-08
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TSK
DownloadVisualize
BU of 6tsk by Molmil
Beta-galactosidase in complex with L-ribose
Descriptor: Beta-galactosidase, MAGNESIUM ION, beta-L-ribopyranose
Authors:Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
Deposit date:2019-12-20
Release date:2020-01-08
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6NZG
DownloadVisualize
BU of 6nzg by Molmil
Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine
Descriptor: (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, Beta-galactosidase, CALCIUM ION, ...
Authors:Pellock, S.J, Jariwala, P.B, Redinbo, M.R.
Deposit date:2019-02-13
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling.
Acs Chem.Biol., 15, 2020
6U7I
DownloadVisualize
BU of 6u7i by Molmil
Faecalibacterium prausnitzii Beta-glucuronidase
Descriptor: Beta-glucuronidase
Authors:Ervin, S.M, Redinbo, M.R.
Deposit date:2019-09-03
Release date:2019-10-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gut microbial beta-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens.
J.Biol.Chem., 294, 2019
6U7J
DownloadVisualize
BU of 6u7j by Molmil
Uncultured Clostridium sp. Beta-glucuronidase
Descriptor: Beta-glucuronidase, CALCIUM ION
Authors:Ervin, S.M, Redinbo, M.R.
Deposit date:2019-09-03
Release date:2019-10-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Gut microbial beta-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens.
J.Biol.Chem., 294, 2019
6HPD
DownloadVisualize
BU of 6hpd by Molmil
The structure of a beta-glucuronidase from glycoside hydrolase family 2
Descriptor: BROMIDE ION, Beta-galactosidase (GH2), MAGNESIUM ION
Authors:Robb, C.S, Gerlach, N, Reisky, L, Bornshoeru, U, Hehemann, J.H.
Deposit date:2018-09-20
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan.
Nat.Chem.Biol., 15, 2019
6D7J
DownloadVisualize
BU of 6d7j by Molmil
The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site
Descriptor: Beta-Glucuronidase, GLYCEROL, POTASSIUM ION, ...
Authors:Little, M.S, Redinbo, M.R.
Deposit date:2018-04-24
Release date:2019-05-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Active site flexibility revealed in crystal structures of Parabacteroides merdae beta-glucuronidase from the human gut microbiome.
Protein Sci., 27, 2018
6CXS
DownloadVisualize
BU of 6cxs by Molmil
Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine
Descriptor: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein
Authors:Wallace, B.D, Redinbo, M.R.
Deposit date:2018-04-04
Release date:2019-04-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy.
Proc.Natl.Acad.Sci.USA, 2020
6NCY
DownloadVisualize
BU of 6ncy by Molmil
Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans
Descriptor: Beta-glucuronidase, GLYCEROL, NICKEL (II) ION, ...
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCZ
DownloadVisualize
BU of 6ncz by Molmil
Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans bound to phenyl-thio-beta-D-glucuronide
Descriptor: Beta-glucuronidase, GLYCEROL, phenyl 1-thio-beta-D-glucopyranosiduronic acid
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6EC6
DownloadVisualize
BU of 6ec6 by Molmil
Ruminococcus gnavus Beta-glucuronidase
Descriptor: Beta-glucuronidase, CHLORIDE ION, GLYCEROL
Authors:Biernat, K.A, Redinbo, M.R.
Deposit date:2018-08-07
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ED2
DownloadVisualize
BU of 6ed2 by Molmil
Faecalibacterium prausnitzii beta-glucuronidase
Descriptor: FORMIC ACID, GLYCEROL, Glycosyl hydrolase family 2, ...
Authors:Pellock, S.J, Biernat, K.A, Redinbo, M.R.
Deposit date:2018-08-08
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ECA
DownloadVisualize
BU of 6eca by Molmil
Lactobacillus rhamnosus Beta-glucuronidase
Descriptor: Beta-glucuronidase, CHLORIDE ION, GLYCEROL
Authors:Biernat, K.A, Pellock, S.J, Bhatt, A.P, Bivins, M.M, Walton, W.G, Tran, B.N.T, Wei, L, Snider, M.C, Cesmat, A.P, Tripathy, A, Erie, D.A, Redinbo, M.R.R.
Deposit date:2018-08-07
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ED1
DownloadVisualize
BU of 6ed1 by Molmil
Bacteroides dorei Beta-glucuronidase
Descriptor: Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION
Authors:Biernat, K.A, Redinbo, M.R.
Deposit date:2018-08-08
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6MVF
DownloadVisualize
BU of 6mvf by Molmil
Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6
Descriptor: Beta-galactosidase/beta-glucuronidase, FLAVIN MONONUCLEOTIDE
Authors:Pellock, S.J, Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
5Z19
DownloadVisualize
BU of 5z19 by Molmil
The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine
Descriptor: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Beta-glucuronidase
Authors:Dashnyam, P, Lin, H.Y, Lin, C.H.
Deposit date:2017-12-25
Release date:2018-12-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z1A
DownloadVisualize
BU of 5z1a by Molmil
The crystal structure of Bacteroides fragilis beta-glucuronidase in complex with uronic isofagomine
Descriptor: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Putative beta-galactosidase
Authors:Dashnyam, P, Lin, H.Y, Lin, C.H.
Deposit date:2017-12-25
Release date:2018-12-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z18
DownloadVisualize
BU of 5z18 by Molmil
The crystal structure of Ruminococcus gnavus beta-glucuronidase
Descriptor: Beta-glucuronidase
Authors:Dashnyam, P, Lin, H.Y, Lin, C.H.
Deposit date:2017-12-25
Release date:2018-12-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z1B
DownloadVisualize
BU of 5z1b by Molmil
Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide
Descriptor: 3-HYDROXY-2H-CHROMEN-2-ONE, Glycosyl hydrolase family 2, TIM barrel domain protein, ...
Authors:Dashnyam, P, Lin, H.Y, Lin, C.H.
Deposit date:2017-12-25
Release date:2018-12-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
6D6W
DownloadVisualize
BU of 6d6w by Molmil
Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate
Descriptor: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ...
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-04-23
Release date:2018-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8G
DownloadVisualize
BU of 6d8g by Molmil
D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2
Descriptor: Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D1N
DownloadVisualize
BU of 6d1n by Molmil
Apo structure of Bacteroides uniformis Beta-glucuronidase 1
Descriptor: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D41
DownloadVisualize
BU of 6d41 by Molmil
Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone
Descriptor: (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, ...
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-04-17
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018

221051

数据于2024-06-12公开中

PDB statisticsPDBj update infoContact PDBjnumon