PDB: 11971 resultsInfo pagesStatus searchChemie searchBIRD

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3AN2	The structure of the centromeric nucleosome containing CENP-A Descriptor: 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. Deposit date: 2010-08-27 Release date: 2011-07-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystal structure of the human centromeric nucleosome containing CENP-A Nature, 476, 2011
6KIW	Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
7JZV	Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome Descriptor: BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... Authors: Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. Deposit date: 2020-09-02 Release date: 2021-02-17 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Nat.Struct.Mol.Biol., 28, 2021
6KIZ	Cryo-EM structure of human MLL1-NCP complex, binding mode2 Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIX	Cryo-EM structure of human MLL1-NCP complex, binding mode1 Descriptor: DNA (145-MER), GLUTAMINE, Histone H2A, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
4X23	CRYSTAL STRUCTURE OF CENP-C IN COMPLEX WITH THE NUCLEOSOME CORE PARTICLE Descriptor: CENP-C, DNA (147-MER), Histone H2A, ... Authors: Jiang, J.S. Deposit date: 2014-11-25 Release date: 2014-12-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. Science, 340, 2013
6XPQ	Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) Descriptor: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2020-07-08 Release date: 2021-05-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (4.2 Å) Cite: A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
9EGY	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27 Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Markert, J, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
9EGX	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27 Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Markert, J, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
9EGZ	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27 Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Markert, J.W, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
9EH0	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 30 bp upstream Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Markert, J, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-02-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
9EH2	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Markert, J, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-02-12 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
1F5U	SOLUTION STRUCTURE OF THE KISSING DIMER OF H3 GACG STEM-LOOP IN THE 5'-END DIMERIZATION SIGNAL OF MOLONEY MURINE LEUKEMIA VIRUS GENOMIC RNA Descriptor: RNA (5'-R(*GP*GP*UP*GP*GP*GP*AP*GP*AP*CP*GP*UP*CP*CP*CP*AP*CP*C)-3') Authors: Kim, C.-H, Tinoco Jr, I. Deposit date: 2000-06-16 Release date: 2000-08-21 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: A retroviral RNA kissing complex containing only two G.C base pairs. Proc.Natl.Acad.Sci.USA, 97, 2000
9EH1	RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 20 bp upstream Descriptor: DNA-directed RNA polymerase I, II, and III subunit RPABC5, ... Authors: Markert, J, Farnung, L. Deposit date: 2024-11-21 Release date: 2024-12-18 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription. Science, 387, 2025
5GH9	Crystal structure of CBP Bromodomain with H3K56ac peptide Descriptor: CREB-binding protein, Histone H3 Authors: Xu, L. Deposit date: 2016-06-19 Release date: 2017-06-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.451 Å) Cite: Structural insight into CBP bromodomain-mediated recognition of acetylated histone H3K56ac FEBS J., 2017
5B32	The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... Authors: Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. Deposit date: 2016-02-08 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
5B33	The crystal structure of the H2AZ nucleosome with H3.3. Descriptor: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... Authors: Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. Deposit date: 2016-02-08 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.925 Å) Cite: Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
7CRO	NSD2 bearing E1099K/T1150A dual mutation in complex with 187-bp NCP Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ... Authors: Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. Deposit date: 2020-08-14 Release date: 2020-10-21 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
7CRR	Native NSD3 bound to 187-bp nucleosome Descriptor: DNA (168-MER), DNA(168-MER), Histone H2A, ... Authors: Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. Deposit date: 2020-08-14 Release date: 2020-10-21 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.48 Å) Cite: Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
9GXA	CENP-A/H4 di-tetrasome assembled on alpha-satellite DNA. Descriptor: 147 bp alpha-satellite DNA, 147 bp human alpha-satellite DNA, Histone H3-like centromeric protein A, ... Authors: Ali-Ahmad, A, Sekulic, N. Deposit date: 2024-09-29 Release date: 2025-01-29 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (4.01 Å) Cite: Non-nucleosomal (CENP-A/H4) 2 - DNA complexes as a possible platform for centromere organization. Biorxiv, 2025
6VYP	Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate Descriptor: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ... Authors: Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T. Deposit date: 2020-02-27 Release date: 2020-05-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.99 Å) Cite: Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate. Mol.Cell, 78, 2020
7CRQ	NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode) Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ... Authors: Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. Deposit date: 2020-08-14 Release date: 2020-10-21 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
7CRP	NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ... Authors: Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. Deposit date: 2020-08-14 Release date: 2020-10-21 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
7E9F	Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ... Authors: Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. Deposit date: 2021-03-04 Release date: 2022-09-07 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (4 Å) Cite: Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published
7E9C	Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ... Authors: Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. Deposit date: 2021-03-04 Release date: 2022-09-07 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published

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