PDB: 82129 resultsInfo pagesStatus searchChemie searchBIRD

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8W19	Cryo-EM structure of BTV star-subcore Descriptor: Core protein VP3, VP6 Authors: Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. Deposit date: 2024-02-15 Release date: 2024-04-24 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
8W12	Cryo-EM structure of VP3-VP6 heterohexamer Descriptor: Core protein VP3, VP6 Authors: Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. Deposit date: 2024-02-14 Release date: 2024-04-24 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
8W0Z	Human LCAD complexed with Lauric Acid Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LAURIC ACID, Long-chain specific acyl-CoA dehydrogenase, ... Authors: Xia, C, Kim, J.J.P. Deposit date: 2024-02-14 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
8W0U	Human LCAD complexed with Acetoacetyl Coenzyme A Descriptor: ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ... Authors: Xia, C, Kim, J.J.P. Deposit date: 2024-02-14 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
8W0T	Human LCAD Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, mitochondrial Authors: Xia, C, Kim, J.J.P. Deposit date: 2024-02-14 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
8W0S	Human EBP complexed with compound 3a Descriptor: 1-methyl-8-[(oxan-4-yl)methyl]-3-[4-(trifluoromethyl)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Authors: Sun, D, Masureel, M. Deposit date: 2024-02-14 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. J.Med.Chem., 67, 2024
8W0R	Human EBP complexed with compound 1 Descriptor: 1-methyl-1'-[(oxan-4-yl)methyl]-5-(trifluoromethyl)spiro[indole-2,4'-piperidin]-3(1H)-one, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Authors: Sun, D, Masureel, M. Deposit date: 2024-02-14 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. J.Med.Chem., 67, 2024
8W0L	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor and CoA Descriptor: 5'-O-{(S)-hydroxy[(prop-2-yn-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor and CoA To be published
8W0J	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor Descriptor: 5'-O-{(S)-hydroxy[(prop-2-yn-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor To be published
8W0H	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor (trigonal form) Descriptor: 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor (trigonal form) To be published
8W0D	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor Descriptor: 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor To be published
8W0C	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopentyl ester AMP inhibitor Descriptor: 5'-O-[(S)-(cyclopentyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopentyl ester AMP inhibitor To be published
8W0B	Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopropyl AMP ester inhibitor Descriptor: 5'-O-[(R)-(cyclopropyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase 2, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-02-13 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopropyl AMP ester inhibitor To be published
8W04	Crystal structure of DUF1735-domain containing protein (GH18-like) from Bacteroides faecium at 2.9 A resolution (Space group P21) Descriptor: DUF1735 domain-containing protein Authors: Sastre, D.E, Navarro, M.V.A.S, Sultana, N, Sundberg, E.J. Deposit date: 2024-02-13 Release date: 2024-05-29 Last modified: 2024-06-26 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. Nat Commun, 15, 2024
8W01	Crystal structure of DUF1735 domain-containing protein (GH18-like) from Bacteroides faecium at 2.7 A resolution (Space group C2) Descriptor: DUF1735 domain-containing protein Authors: Sastre, D.E, Navarro, M.V.A.S, Sultana, N, Sundberg, E.J. Deposit date: 2024-02-13 Release date: 2024-05-29 Last modified: 2024-06-26 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. Nat Commun, 15, 2024
8VZ9	Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... Authors: Ciacchi, L, Rossjohn, J, Awad, W. Deposit date: 2024-02-11 Release date: 2024-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil. J.Biol.Chem., 300, 2024
8VZ8	Crystal structure of mouse MAIT M2B TCR-MR1-5-OP-RU complex Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... Authors: Ciacchi, L, Rossjohn, J, Awad, W. Deposit date: 2024-02-11 Release date: 2024-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil. J.Biol.Chem., 300, 2024
8VW4	Crystal structure of Cbl-b TKB bound to compound 26 Descriptor: (7-methoxy-2-{2-[(1S,3S,4S)-3-(3-methoxy-2-methyl-5-nitrophenyl)-1-methyl-5-oxo-1,5-dihydroimidazo[1,5-a]pyridin-2(3H)-yl]-2-oxoethoxy}quinolin-8-yl)acetic acid, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase CBL-B, ... Authors: Yu, C, Murray, J, Hsu, P.L. Deposit date: 2024-01-31 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding. Acs Med.Chem.Lett., 15, 2024
8VW2	Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (ATP bound) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-01-31 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (ATP bound) To be published
8VW1	Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (ADP bound) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-01-31 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (ADP bound) To be published
8VW0	Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-01-31 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) To be published
8VTT	Meis1 homeobox domain bound to neomycin fragment Descriptor: Homeobox protein Meis1, RIBOSTAMYCIN, SULFATE ION Authors: Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N, Sadek, H.A. Deposit date: 2024-01-27 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals to be published
8VTS	Meis1 homeobox domain bound to paromomycin fragment Descriptor: 1,2-ETHANEDIOL, Homeobox protein Meis1, ISOPROPYL ALCOHOL, ... Authors: Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N. Deposit date: 2024-01-27 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals to be published
8VTO	Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-methylphenylalanine Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... Authors: Tran, K, Mathews, I, Boxer, S.G. Deposit date: 2024-01-26 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-methylphenylalanine To Be Published
8VTN	Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-nitrophenylalanine Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... Authors: Tran, K, Mathews, I, Boxer, S.G. Deposit date: 2024-01-26 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (3.57 Å) Cite: Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant Y(M210)2-nitrophenylalanine To Be Published

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