PDB: 48855 resultsInfo pagesStatus searchChemie searchBIRD

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6ZH8	Cryo-EM structure of DNA-PKcs:DNA Descriptor: DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*T)-3'), DNA-dependent protein kinase catalytic subunit,DNA-PKcs Authors: Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. Deposit date: 2020-06-21 Release date: 2020-10-21 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.14 Å) Cite: Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
4FJL	RB69 DNA polymerase ternary complex with dGTP/dA Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.87 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
3G97	GR DNA-binding domain:GilZ 16bp complex-9 Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), ... Authors: Pufall, M.A, Yamamoto, K.R, Meijsing, S.H. Deposit date: 2009-02-13 Release date: 2009-04-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.08 Å) Cite: DNA binding site sequence directs glucocorticoid receptor structure and activity. Science, 324, 2009
4FJ9	RB69 DNA polymerase ternary complex with dTTP/dT Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.97 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJX	RB69 DNA polymerase ternary complex with dATP/dG Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.11 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJM	RB69 DNA polymerase ternary complex with dCTP/dA Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.02 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJN	RB69 DNA polymerase ternary complex with dTTP/dA Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.98 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
3G9M	GR DNA-binding domain:Sgk 16bp complex-44 Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*T)-3'), ... Authors: Pufall, M.A, Yamamoto, K.R, Meijsing, S.H. Deposit date: 2009-02-13 Release date: 2009-04-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.61 Å) Cite: DNA binding site sequence directs glucocorticoid receptor structure and activity. Science, 324, 2009
4FJ7	RB69 DNA polymerase ternary complex with dGTP/dT Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FK4	RB69 DNA polymerase ternary complex with dGTP/dG Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJJ	RB69 DNA polymerase ternary complex with dTTP/dC Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FK2	RB69 DNA polymerase ternary complex with dTTP/dG Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.98 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJ8	RB69 DNA polymerase ternary complex with dCTP/dT Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.19 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJ5	RB69 DNA polymerase ternary complex with dATP/dT Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJK	RB69 DNA polymerase ternary complex with dATP/dA Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
3AUO	DNA polymerase X from Thermus thermophilus HB8 ternary complex with 1-nt gapped DNA and ddGTP Descriptor: 1-nt gapped DNA, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase beta family (X family), ... Authors: Nakane, S, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-02-11 Release date: 2012-01-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
4FJG	RB69 DNA polymerase ternary complex with dATP/dC Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.02 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FK0	RB69 DNA polymerase ternary complex with dCTP/dG Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.18 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJH	RB69 DNA polymerase ternary complex with dGTP/dC Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.11 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4KB6	Structure of porcine cyclic GMP AMP synthase (CGAS) in complex with DNA, ATP and GTP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Deimling, T, Hopfner, K.-P. Deposit date: 2013-04-23 Release date: 2013-06-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.0754 Å) Cite: Structural mechanism of cytosolic DNA sensing by cGAS. Nature, 498, 2013
4FJI	RB69 DNA polymerase ternary complex with dcTP/dC Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
7OTP	DNA-PKcs in complex with ATPgammaS-Mg Descriptor: DNA-dependent protein kinase catalytic subunit,DNA-PKcs, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Liang, S, Thomas, S.E, Blundell, T.L. Deposit date: 2021-06-10 Release date: 2022-01-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Nature, 601, 2022
3AU6	DNA polymerase X from Thermus thermophilus HB8 ternary complex with primer/template DNA and ddGTP Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*TP*(DDG))-3', 5'-D(*CP*GP*GP*CP*CP*AP*TP*AP*CP*TP*G)-3', ... Authors: Nakane, S, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-01-28 Release date: 2012-01-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
6GMY	Tc-DNA/RNA duplex Descriptor: RNA (5'-R(*GP*UP*AP*AP*GP*CP*CP*GP*AP*G)-3'), Tc-DNA (5'-(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3') Authors: Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C. Deposit date: 2018-05-28 Release date: 2018-06-13 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. Nucleic Acids Res., 47, 2019
3AU2	DNA polymerase X from Thermus thermophilus HB8 complexed with Ca-dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Nakane, S, Ishikawa, H, Wakamatsu, T, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-01-28 Release date: 2012-01-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012

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