5GY6
 
 | | Ribonuclease from Hericium erinaceus (RNase He1) | | Descriptor: | Ribonuclease T1, ZINC ION | | Authors: | Kobayashi, H, Sangawa, T, Takebe, K, Itagaki, T, Motoyoshi, N, Suzuki, M. | | Deposit date: | 2016-09-21 | | Release date: | 2017-09-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Ribonuclease from Hericium erinaceus (RNase He1)
To Be Published
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2SAR
 | | DETERMINATION AND RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURES OF RIBONUCLEASE SA AND ITS COMPLEX WITH 3'-GUANYLIC ACID AT 1.8 ANGSTROMS RESOLUTION | | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | | Authors: | Sevcik, J, Dodson, E.J, Dodson, G.G. | | Deposit date: | 1990-12-13 | | Release date: | 1992-04-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Determination and restrained least-squares refinement of the structures of ribonuclease Sa and its complex with 3'-guanylic acid at 1.8 A resolution.
Acta Crystallogr.,Sect.B, 47, 1991
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2RBI
 | | STRUCTURE OF BINASE MUTANT HIS 101 ASN | | Descriptor: | RIBONUCLEASE | | Authors: | Offen, W.A, Okorokov, A.L. | | Deposit date: | 1996-11-12 | | Release date: | 1997-03-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations.
Protein Eng., 10, 1997
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5HOH
 | | RIBONUCLEASE T1 (ASN9ALA/THR93ALA DOUBLEMUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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2RNT
 | | THREE-DIMENSIONAL STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE AT 1.8 ANGSTROMS RESOLUTION | | Descriptor: | CALCIUM ION, GUANYLYL-2',5'-PHOSPHOGUANOSINE, RIBONUCLEASE T1 | | Authors: | Saenger, W, Koepke, J, Maslowska, M, Heinemann, U. | | Deposit date: | 1988-07-06 | | Release date: | 1989-10-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Three-dimensional structure of ribonuclease T1 complexed with guanylyl-2',5'-guanosine at 1.8 A resolution.
J.Mol.Biol., 206, 1989
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4HOH
 | | RIBONUCLEASE T1 (THR93ALA MUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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4J5G
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1MGR
 | | Crystal structure of RNase Sa3,cytotoxic microbial ribonuclease | | Descriptor: | Guanyl-specific ribonuclease Sa3, SULFATE ION | | Authors: | Sevcik, J, Urbanikova, L, Leland, P.A, Raines, R.T. | | Deposit date: | 2002-08-16 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Links X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
J.Biol.Chem., 277, 2002
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1MGW
 | | Crystal structure of RNase Sa3, cytotoxic microbial ribonuclease | | Descriptor: | Guanyl-specific ribonuclease Sa3, LITHIUM ION | | Authors: | Sevcik, J, Urbanikova, L, Leland, P.A, Raines, R.T. | | Deposit date: | 2002-08-16 | | Release date: | 2003-02-04 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Links X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
J.Biol.Chem., 277, 2002
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4GSP
 | | RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS | | Descriptor: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ... | | Authors: | Zegers, I, Wyns, L. | | Deposit date: | 1997-12-02 | | Release date: | 1998-08-12 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
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4BIR
 | | RIBONUCLEASE T1: FREE HIS92GLN MUTANT | | Descriptor: | CALCIUM ION, GUANYL-SPECIFIC RIBONUCLEASE T1 | | Authors: | Doumen, J, Steyaert, J. | | Deposit date: | 1998-01-13 | | Release date: | 1998-07-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
Biochemistry, 31, 1992
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1PY3
 | | Crystal structure of Ribonuclease Sa2 | | Descriptor: | SULFATE ION, ribonuclease | | Authors: | Sevcik, J, Dauter, Z, Wilson, K.S. | | Deposit date: | 2003-07-08 | | Release date: | 2004-07-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2.
Acta Crystallogr.,Sect.D, 60, 2004
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1PYL
 | | Crystal structure of Ribonuclease Sa2 | | Descriptor: | SULFATE ION, ribonuclease | | Authors: | Sevcik, J, Dauter, Z, Wilson, K.S. | | Deposit date: | 2003-07-09 | | Release date: | 2004-07-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.507 Å) | | Cite: | Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2.
Acta Crystallogr.,Sect.D, 60, 2004
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4BU4
 | | RIBONUCLEASE T1 COMPLEX WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
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3WR2
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3WHO
 | | X-ray-Crystallographic Structure of an RNase Po1 Exhibiting Anti-tumor Activity | | Descriptor: | Guanyl-specific ribonuclease Po1 | | Authors: | Kobayashi, H, Katsurtani, T, Hara, Y, Motoyoshi, N, Itagaki, T, Akita, F, Higashiura, A, Yamada, Y, Suzuki, M, Inokuchi, N. | | Deposit date: | 2013-08-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | X-ray crystallographic structure of RNase Po1 that exhibits anti-tumor activity.
Biol.Pharm.Bull., 37, 2014
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4J5K
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3BU4
 | | RIBONUCLEASE T1 COMPLEX WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
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2BU4
 | | RIBONUCLEASE T1 COMPLEX WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
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2HOH
 | | RIBONUCLEASE T1 (N9A MUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PHOSPHATE ION, ... | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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3A5E
 | | Crystal structure of 5K RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa | | Authors: | Takano, K. | | Deposit date: | 2009-08-06 | | Release date: | 2010-08-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins
Protein Sci., 19, 2010
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3AGO
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3AHW
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3D5G
 | | Structure of ribonuclease Sa2 complexes with mononucleotides: new aspects of catalytic reaction and substrate recognition | | Descriptor: | Ribonuclease, SULFATE ION | | Authors: | Bauerova-Hlinkova, V, Dvorsky, R, Povazanec, F, Sevcik, J. | | Deposit date: | 2008-05-16 | | Release date: | 2009-05-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition
Febs J., 276, 2009
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3DGY
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