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2R9Y
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BU of 2r9y by Molmil
Structure of antiplasmin
Descriptor: Alpha-2-antiplasmin
Authors:Law, R.H.P, Sofian, T, Kan, W.T, Horvath, A.J, Hitchen, C.R, Langendorf, C.G, Buckle, A.M, Whisstock, J.C, Coughlin, P.B.
Deposit date:2007-09-14
Release date:2007-12-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray crystal structure of the fibrinolysis inhibitor {alpha}2-antiplasmin
Blood, 111, 2008
2RIV
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BU of 2riv by Molmil
Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin
Descriptor: GLYCEROL, SULFATE ION, Thyroxine-binding globulin
Authors:Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W.
Deposit date:2007-10-12
Release date:2008-10-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
2RIW
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BU of 2riw by Molmil
The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin
Authors:Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W.
Deposit date:2007-10-12
Release date:2008-10-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
4IC0
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BU of 4ic0 by Molmil
Crystal Structure of PAI-1 in Complex with Gallate
Descriptor: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1
Authors:Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D.
Deposit date:2012-12-09
Release date:2013-12-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal Structure of PAI-1 in Complex with Gallate
To be Published
8GXV
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BU of 8gxv by Molmil
Structure of a bacterial serpin Choloropin derived from Cholorobium limicola
Descriptor: GLYCEROL, Proteinase inhibitor I4 serpin, ZINC ION
Authors:Zhou, A, Xu, J.
Deposit date:2022-09-21
Release date:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Climpin, a Novel Bacterial a Serpin inducing a Broad Range of Proteases and Regulated by Heparin and DNA.
To Be Published
5C98
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BU of 5c98 by Molmil
1.45A resolution structure of SRPN18 from Anopheles gambiae
Descriptor: AGAP007691-PB
Authors:Lovell, S, Battaile, K.P, Gulley, M, Zhang, X, Meekins, D.A, Gao, F.P, Michel, K.
Deposit date:2015-06-26
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae.
Acta Crystallogr F Struct Biol Commun, 72, 2016
8H55
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BU of 8h55 by Molmil
The structure of zebrafish angiotensinogen
Descriptor: Angiotensinogen, SULFATE ION
Authors:Zhou, A, Wei, H.
Deposit date:2022-10-12
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:BIOLOGICAL IMPLICATIONS OF A 2 ANGSTROMS STRUCTURE OF DIMERIC ANGIOTENSINOGEN
To Be Published
5EI0
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BU of 5ei0 by Molmil
Structure of RCL-cleaved vaspin (serpinA12)
Descriptor: Serpin A12
Authors:Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N.
Deposit date:2015-10-29
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of cleaved vaspin (serpinA12).
Biol.Chem., 397, 2016
8PI2
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BU of 8pi2 by Molmil
Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser)
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antitrypsin, DIMETHYL SULFOXIDE, ...
Authors:Wang, M, Irving, J.A.
Deposit date:2023-06-20
Release date:2023-07-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural determinants of instability in alpha-1-antitrypsin
To Be Published
8H4X
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BU of 8h4x by Molmil
Structure of cleaved Serpin B9
Descriptor: 1,2-ETHANEDIOL, Serpin B9, ZINC ION
Authors:Zhou, A, Yan, T.
Deposit date:2022-10-11
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Expression, purification and crystallization of cleaved Serpin B9
To Be Published
8P4J
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BU of 8p4j by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
Descriptor: Alpha-1-antitrypsin
Authors:Kamuda, K, Lomas, D.A, Irving, J.A.
Deposit date:2023-05-22
Release date:2024-04-03
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
5DU3
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BU of 5du3 by Molmil
Active form of human C1-inhibitor
Descriptor: Plasma protease C1 inhibitor
Authors:Pannu, N.S, Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A.
Deposit date:2015-09-18
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
8P4U
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BU of 8p4u by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
Descriptor: Alpha-1-antitrypsin
Authors:Kamuda, K, Lomas, D.A, Irving, J.A.
Deposit date:2023-05-23
Release date:2024-04-03
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
4IF8
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BU of 4if8 by Molmil
Structure Of Vaspin
Descriptor: SULFATE ION, Serpin A12
Authors:Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G.
Deposit date:2012-12-14
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Vaspin inhibits kallikrein 7 by serpin mechanism
Cell.Mol.Life Sci., 70, 2013
5DUQ
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BU of 5duq by Molmil
Active human c1-inhibitor in complex with dextran sulfate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma protease C1 inhibitor, SULFITE ION, ...
Authors:Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A, Pannu, N.S.
Deposit date:2015-09-20
Release date:2016-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
5HGC
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BU of 5hgc by Molmil
A Serpin structure
Descriptor: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, SULFATE ION, ...
Authors:Das, S, Vashchenko, G.V, Van Petegem, F.
Deposit date:2016-01-08
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A Serpin structure
J.Biol.Chem., 2016
4KDS
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BU of 4kds by Molmil
Crystal structure of latent rainbow trout plasminogen activator inhibitor 1 (PAI-1)
Descriptor: Plasminogen activator inhibitor 1, SULFATE ION
Authors:Johansen, J.S.
Deposit date:2013-04-25
Release date:2013-05-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6682 Å)
Cite:Protein conformational change delayed by steric hindrance from an N-linked glycan.
J.Mol.Biol., 425, 2013
1F0C
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BU of 1f0c by Molmil
STRUCTURE OF THE VIRAL SERPIN CRMA
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ICE INHIBITOR
Authors:Renatus, M, Zhou, Q, Stennicke, H.R, Snipas, S.J, Turk, D, Bankston, L.A, Liddington, R.C, Salvesen, G.S.
Deposit date:2000-05-15
Release date:2000-09-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of the apoptotic suppressor CrmA in its cleaved form.
Structure Fold.Des., 8, 2000
3STO
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BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
Descriptor: Serine protease inhibitor
Authors:Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
Deposit date:2011-07-11
Release date:2012-05-30
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
7QRN
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BU of 7qrn by Molmil
Crystal structure of Ovalbumin-related protein X (OVAX) complexed with fondaparinux
Descriptor: 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Ovalbumin-related protein X, ...
Authors:Coste, F, Bruneau, G, Rehault-Godbert, S.
Deposit date:2022-01-11
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Antimicrobial Proteins and Peptides in Avian Eggshell: Structural Diversity and Potential Roles in Biomineralization.
Front Immunol, 13, 2022
7QR2
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BU of 7qr2 by Molmil
Crystal structure of chicken Ovalbumin-related protein X
Descriptor: 1,2-ETHANEDIOL, Ovalbumin-related protein X, SULFATE ION
Authors:Coste, F, Rehault-Godbert, S.
Deposit date:2022-01-10
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of chicken Ovalbumin-related protein X
To Be Published
7QTZ
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BU of 7qtz by Molmil
Crystal structure of Iripin-1 serpin from tick Ixodes ricinus
Descriptor: MAGNESIUM ION, Putative salivary serpin
Authors:Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules.
Front Immunol, 14, 2023
7RBW
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BU of 7rbw by Molmil
Structure of Biliverdin-binding Serpin of Boana punctata (polka-dot tree frog)
Descriptor: BILIVERDINE IX ALPHA, Biliverdin bindin serpin
Authors:Fedorov, E, Manoilov, K.Y, Verkhusha, V, Almo, S.C, Ghosh, A.
Deposit date:2021-07-06
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily.
J.Mol.Biol., 434, 2021
2HI9
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BU of 2hi9 by Molmil
Crystal Structure of human native protein C inhibitor
Descriptor: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor
Authors:Li, W, Adams, T.E, Huntington, J.A.
Deposit date:2006-06-29
Release date:2007-03-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
2HIJ
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BU of 2hij by Molmil
Crystal Structure of P14 Alanine Variant of Antithrombin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
Authors:Luis, S.A, Bock, S.C, Huntington, J.A.
Deposit date:2006-06-29
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of P14 Alanine Variant of Antithrombin
To be Published

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数据于2024-07-17公开中

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