PDB: 72678 resultsInfo pagesStatus searchChemie searchBIRD

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5NKK	SMG8-SMG9 complex GDP bound Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Li, L, Basquin, J, Conti, E. Deposit date: 2017-03-31 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins. RNA, 23, 2017
7SZU	Crystal structure of Pepper RNA aptamer in complex with HBC ligand and Fab BL3-6 Descriptor: 4-[(~{Z})-1-cyano-2-[4-[2-hydroxyethyl(methyl)amino]phenyl]ethenyl]benzenecarbonitrile, BL3-6 Fab heavy chain, BL3-6 Fab light chain, ... Authors: Rees, H.C, Piccirilli, J.A. Deposit date: 2021-11-29 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Structural Basis for Fluorescence Activation by Pepper RNA. Acs Chem.Biol., 17, 2022
7MKJ	Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Saecker, R.M, Darst, S.A, Chen, J. Deposit date: 2021-04-23 Release date: 2021-09-29 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Saecker, R.M, Darst, S.A, Chen, J. Deposit date: 2021-04-23 Release date: 2021-09-29 Last modified: 2021-10-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKE	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Saecker, R.M, Darst, S.A, Chen, J. Deposit date: 2021-04-23 Release date: 2021-09-29 Last modified: 2021-10-13 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
2DQP	Structural analyses of DNA:DNA and RNA:DNA duplexes containing 5-(N-aminohexyl)carbamoyl modified uridines Descriptor: (6-AMINOHEXYL)CARBAMIC ACID, DNA (5'-D(*DCP*(OMU)P*DCP*DTP*(OMU)P*DCP*DTP*DTP*DC)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3') Authors: Juan, E.C.M, Kondo, J, Ito, T, Ueno, Y, Matsuda, A, Takenaka, A. Deposit date: 2006-05-29 Release date: 2007-04-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules Nucleic Acids Res., 35, 2007
5ID6	Structure of Cpf1/RNA Complex Descriptor: Cpf1, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3') Authors: Dong, D, Ren, K, Qiu, X, Wang, J, Huang, Z. Deposit date: 2016-02-24 Release date: 2016-04-27 Last modified: 2016-05-11 Method: X-RAY DIFFRACTION (2.382 Å) Cite: The crystal structure of Cpf1 in complex with CRISPR RNA Nature, 532, 2016
5X89	The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri Descriptor: EndA-like protein,tRNA-splicing endonuclease, PHOSPHATE ION Authors: Kaneta, A, Fujishima, K, Morikazu, W, Hori, H, Hirata, A. Deposit date: 2017-03-01 Release date: 2018-01-24 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.53 Å) Cite: The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity Nucleic Acids Res., 46, 2018
4E78	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin loop deletion bound to primer-template RNA with 3'-dG Descriptor: 5'-R(*U*AP*CP*CP*GP*(GDO))-3', PROTEIN (RNA-directed RNA polymerase) Authors: Edwards, T.E, Mosley, R.T. Deposit date: 2012-03-16 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
1ZL3	Coupling of active site motions and RNA binding Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA pseudouridine synthase B Authors: Hoang, C, Hamilton, C.S, Mueller, E.G, Ferre-D'Amare, A.R. Deposit date: 2005-05-05 Release date: 2005-08-09 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain Protein Sci., 14, 2005
6NMA	CryoEM structure of the LbCas12a-crRNA-AcrVA4 complex Descriptor: AcrVA1, Cpf1, MAGNESIUM ION, ... Authors: Chang, L, Li, Z, Zhang, H. Deposit date: 2019-01-10 Release date: 2019-06-12 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
3SAF	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
6NM9	CryoEM structure of the LbCas12a-crRNA-AcrVA4 dimer Descriptor: AcrVA4, Cpf1, MAGNESIUM ION, ... Authors: Chang, L, Li, Z, Zhang, H. Deposit date: 2019-01-10 Release date: 2019-06-12 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
3SAH	Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SAG	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
5FW3	Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... Authors: Anders, C, Bargsten, K, Jinek, M. Deposit date: 2016-02-11 Release date: 2016-06-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
6NMC	CryoEM structure of the LbCas12a-crRNA-2xAcrVA1 complex Descriptor: AcrVA1, Cpf1, MAGNESIUM ION, ... Authors: Chang, L, Li, Z, Zhang, H. Deposit date: 2019-01-10 Release date: 2019-06-12 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.24 Å) Cite: Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
6OMV	CryoEM structure of the LbCas12a-crRNA-AcrVA4-DNA complex Descriptor: AcrVA4, Cpf1, DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*GP*GP*A)-3'), ... Authors: Chang, L, Li, Z, Zhang, H. Deposit date: 2019-04-19 Release date: 2019-06-12 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
6KL9	Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) Descriptor: AcrVA4, LbCas12a, MAGNESIUM ION, ... Authors: Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. Deposit date: 2019-07-30 Release date: 2019-09-11 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
7MKT	Crystal structure of r(GU)11G-NMM complex Descriptor: N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') Authors: Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. Deposit date: 2021-04-26 Release date: 2022-11-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.97 Å) Cite: An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
6BBO	Crystal structure of human APOBEC3H/RNA complex Descriptor: APOBEC3H, GLYCEROL, MCherry fluorescent protein, ... Authors: Shaban, N.M, Shi, K, Banerjee, S, Harris, R.S, Aihara, H. Deposit date: 2017-10-19 Release date: 2018-01-10 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.428 Å) Cite: The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol. Cell, 69, 2018
5T3K	Fluorescence detection of RNA-ligand binding and crystal structure determination of ribosomal decoding site RNA using a heavy atom containing fluorescent ribonucleoside Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*AP*GP*CP*GP*(75B)P*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*UP*GP*G)-3') Authors: Hermann, T, Boerneke, M.A. Deposit date: 2016-08-25 Release date: 2017-07-05 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.142 Å) Cite: Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe. Angew. Chem. Int. Ed. Engl., 56, 2017
5FW2	Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... Authors: Anders, C, Bargsten, K, Jinek, M. Deposit date: 2016-02-11 Release date: 2016-06-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.676 Å) Cite: Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
5X6C	Crystal structure of SepRS-SepCysE from Methanocaldococcus jannaschii Descriptor: ADENOSINE-5'-TRIPHOSPHATE, O-phosphoserine--tRNA(Cys) ligase, SULFATE ION, ... Authors: Chen, M, Kato, K, Yao, M. Deposit date: 2017-02-21 Release date: 2017-12-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural basis for tRNA-dependent cysteine biosynthesis Nat Commun, 8, 2017
4Q96	CID of human RPRD1B in complex with an unmodified CTD peptide Descriptor: RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ... Authors: Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) Deposit date: 2014-04-29 Release date: 2014-06-04 Last modified: 2014-08-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014

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