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7Y7G
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BU of 7y7g by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7H
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BU of 7y7h by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7OZ3
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BU of 7oz3 by Molmil
S. agalactiae BusR in complex with its busA-promotor DNA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ...
Authors:Bandera, A.M, Witte, G.
Deposit date:2021-06-25
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
7JT1
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BU of 7jt1 by Molmil
70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound (+9-III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
7JSS
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BU of 7jss by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-15
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
7JT3
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BU of 7jt3 by Molmil
Rotated 70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound in the A site (+9-IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-17
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
7JSZ
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BU of 7jsz by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
7JT2
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BU of 7jt2 by Molmil
70S ribosome stalled on long mRNA with ArfB bound in the A site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
7JSW
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BU of 7jsw by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
8CO2
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BU of 8co2 by Molmil
YdaS N-terminal domain from prophage CP-933P in E. coli O157:H7
Descriptor: ISOPROPYL ALCOHOL, Putative antirepressor protein Cro, SULFATE ION
Authors:Prolic-Kalinsek, M, Loris, R.
Deposit date:2023-02-26
Release date:2023-03-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.63880718 Å)
Cite:YdaS from the Escherichia coli cryptic prophage CP-933P forms an evolutionary link between Cro repressors and HigA antitoxins
To Be Published
8WGN
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BU of 8wgn by Molmil
Human dihydrofolate reductase (HsDHFR) complexed with NADPH and LA1
Descriptor: (3~{E})-3-[[2-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]oxypropoxy]phenyl]methylidene]oxolan-2-one, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Vanichtanankul, J, Saeyang, T, Vitsupakorn, D, Decharuangsilp, S, Arwon, U, Yuthavong, Y, Kamchonwongpaisan, S.
Deposit date:2023-09-22
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flexible 2,4-diaminopyrimidine bearing a butyrolactone as Plasmodium falciparum dihydrofolate reductase inhibitors.
Bioorg.Chem., 153, 2024
1SD7
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BU of 1sd7 by Molmil
Crystal Structure of a SeMet derivative of MecI at 2.65 A
Descriptor: Methicillin resistance regulatory protein mecI
Authors:Safo, M.K, Zhao, Q, Musayev, F.N, Robinson, H, Scarsdale, N, Archer, G.L.
Deposit date:2004-02-13
Release date:2004-02-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons
J.Bacteriol., 187, 2005
3MQ0
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BU of 3mq0 by Molmil
Crystal Structure of Agobacterium tumefaciens repressor BlcR
Descriptor: Transcriptional repressor of the blcABC operon
Authors:Chen, L.
Deposit date:2010-04-27
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:The Agrobacterium tumefaciens Transcription Factor BlcR Is Regulated via Oligomerization.
J.Biol.Chem., 286, 2011
7RGU
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BU of 7rgu by Molmil
The crystal structure of RocC bound to a transcriptional terminator
Descriptor: Modified SL3 of RocR, Repressor of competence, RNA Chaperone
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
8BNY
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BU of 8bny by Molmil
Structure of the tetramerization domain of pLS20 conjugation repressor Rco
Descriptor: CHLORIDE ION, Immunity repressor protein
Authors:Bernardo, N, Crespo, I, Meijer, W.J.J, Boer, D.R.
Deposit date:2022-11-14
Release date:2023-04-19
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.429 Å)
Cite:A tetramerization domain in prokaryotic and eukaryotic transcription regulators homologous to p53.
Acta Crystallogr D Struct Biol, 79, 2023
8JFF
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BU of 8jff by Molmil
Crystal structure of Catabolite repressor acivator from E. coli in complex with HEPES
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Catabolite repressor/activator
Authors:Neetu, N, Katiki, M, Kumar, P.
Deposit date:2023-05-18
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Sulisobenzone is a potent inhibitor of the global transcription factor Cra.
J.Struct.Biol., 215, 2023
3JXB
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BU of 3jxb by Molmil
Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9C
Descriptor: 5'-D(*CP*AP*TP*TP*TP*AP*AP*GP*AP*CP*GP*TP*CP*TP*TP*AP*AP*AP*TP*A)-3', 5'-D(*TP*AP*TP*TP*TP*AP*AP*GP*AP*CP*GP*TP*CP*TP*TP*AP*AP*AP*TP*G)-3', Repressor protein C2
Authors:Watkins, D, Koudelka, G.B, Williams, L.D.
Deposit date:2009-09-18
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Sequence Recognition of DNA by Protein-Induced Conformational Transitions
J.Mol.Biol., 396, 2010
3JXD
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BU of 3jxd by Molmil
Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9C in the presence of Rb+
Descriptor: 5'-D(*CP*AP*TP*TP*TP*AP*AP*GP*AP*CP*GP*TP*CP*TP*TP*AP*AP*AP*TP*G)-3', RUBIDIUM ION, Repressor protein C2
Authors:Watkins, D, Koudelka, G.B, Williams, L.D.
Deposit date:2009-09-18
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sequence Recognition of DNA by Protein-Induced Conformational Transitions.
J.Mol.Biol., 396, 2010
3JXC
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BU of 3jxc by Molmil
Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9T in the presence of Tl+
Descriptor: 5'-D(*CP*AP*TP*TP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*AP*AP*TP*G)-3', Repressor protein C2, THALLIUM (I) ION
Authors:Watkins, D, Koudelka, G.B, Williams, L.D.
Deposit date:2009-09-18
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence Recognition of DNA by Protein-Induced Conformational Transitions.
J.Mol.Biol., 396, 2010
7EQF
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BU of 7eqf by Molmil
Crystal Structure of a Transcription Factor in complex with Ligand
Descriptor: (6~{R})-3-methyl-8-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{R},5~{R},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{S},5~{S},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-oxidanyl-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-1,6,11-tris(oxidanyl)-5,6-dihydrobenzo[a]anthracene-7,12-dione, TetR/AcrR family transcriptional regulator
Authors:Uehara, S, Tsugita, A, Matsui, T, Yokoyama, T, Ostash, I, Ostash, B, Tanaka, Y.
Deposit date:2021-05-01
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK.
Febs J., 289, 2022
7CV2
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BU of 7cv2 by Molmil
Crystal structure of B. halodurans NiaR in niacin-bound form
Descriptor: NICOTINIC ACID, Transcriptional regulator NiaR, ZINC ION
Authors:Lee, J.Y, Lee, D.W, Park, Y.W, Lee, M.Y, Jeong, K.H.
Deposit date:2020-08-25
Release date:2020-12-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans.
Sci Rep, 10, 2020
7CV0
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BU of 7cv0 by Molmil
Crystal structure of B. halodurans NiaR in apo form
Descriptor: Transcriptional regulator NiaR, ZINC ION
Authors:Lee, J.Y, Lee, D.W, Park, Y.W, Lee, M.Y, Jeong, K.H.
Deposit date:2020-08-25
Release date:2020-12-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans.
Sci Rep, 10, 2020
7EN6
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BU of 7en6 by Molmil
The crystal structure of Escherichia coli MurR in apo form
Descriptor: HTH-type transcriptional regulator MurR, PHOSPHATE ION
Authors:Zhang, Y, Chen, W, Ji, Q.
Deposit date:2021-04-16
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.276 Å)
Cite:Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7EN5
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BU of 7en5 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate
Descriptor: 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zhang, Y, Chen, W, Ji, Q.
Deposit date:2021-04-16
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7EN7
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BU of 7en7 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate
Descriptor: (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR
Authors:Zhang, Y, Chen, W, Ji, Q.
Deposit date:2021-04-16
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022

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数据于2024-11-06公开中

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