2O9S
 
 | | The second SH3 domain from ponsin | | Descriptor: | CHLORIDE ION, Ponsin, SODIUM ION, ... | | Authors: | Pinotsis, N, Wilmanns, M. | | Deposit date: | 2006-12-14 | | Release date: | 2007-10-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (0.83 Å) | | Cite: | Paxillin and ponsin interact in nascent costameres of muscle cells
J.Mol.Biol., 369, 2007
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2O9V
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2O88
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2O2W
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2O31
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2NUZ
 | | crystal structure of alpha spectrin SH3 domain measured at room temperature | | Descriptor: | Spectrin alpha chain, brain | | Authors: | Agarwal, V, Faelber, K, Hologne, M, Chevelkov, V, Oschkinat, H, Diehl, A, Reif, B. | | Deposit date: | 2006-11-10 | | Release date: | 2007-05-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Comparison of MAS solid-state NMR and X-ray crystallographic data in the analysis of protein dynamics in the solid state
To be Published
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2JMC
 | | Chimer between Spc-SH3 and P41 | | Descriptor: | Spectrin alpha chain, brain and P41 peptide chimera | | Authors: | van Nuland, N.A.J, Candel, A.M, Martinez, J.C, Conejero-Lara, F, Bruix, M. | | Deposit date: | 2006-11-02 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex
Febs Lett., 581, 2007
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2JMA
 | | R21A Spc-SH3:P41 complex | | Descriptor: | P41 peptide, Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2JM9
 | | R21A Spc-SH3 bound | | Descriptor: | Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2JM8
 | | R21A Spc-SH3 free | | Descriptor: | Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2IIM
 | | SH3 Domain of Human Lck | | Descriptor: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ... | | Authors: | Romir, J, Egerer-Sieber, C, Muller, Y.A. | | Deposit date: | 2006-09-28 | | Release date: | 2006-11-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365, 2007
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2DYB
 | | The crystal structure of human p40(phox) | | Descriptor: | Neutrophil cytosol factor 4 | | Authors: | Honbou, K. | | Deposit date: | 2006-09-08 | | Release date: | 2007-01-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
Embo J., 26, 2007
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2DX1
 | | Crystal structure of RhoGEF protein Asef | | Descriptor: | Rho guanine nucleotide exchange factor 4 | | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-08-22 | | Release date: | 2007-01-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism
J.Biol.Chem., 282, 2007
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2J05
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2J06
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2DVJ
 | | phosphorylated Crk-II | | Descriptor: | V-crk sarcoma virus CT10 oncogene homolog, isoform a | | Authors: | Kobashigawa, Y, Inagaki, F. | | Deposit date: | 2006-07-31 | | Release date: | 2007-05-08 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
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2HDA
 | | Yes SH3 domain | | Descriptor: | Proto-oncogene tyrosine-protein kinase Yes, SULFATE ION | | Authors: | Camara-Artigas, A, Luque, I, Ruiz-Sanz, J, Mateo, P.L, Martin-Garcia, J.M. | | Deposit date: | 2006-06-20 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: Loop flexibility and amyloid aggregation.
Febs Lett., 581, 2007
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2DRK
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2DRM
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2H8H
 | | Src kinase in complex with a quinazoline inhibitor | | Descriptor: | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src | | Authors: | Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. | | Deposit date: | 2006-06-07 | | Release date: | 2006-11-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
J.Med.Chem., 49, 2006
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2DNU
 | | Solution structure of RSGI RUH-061, a SH3 domain from human | | Descriptor: | SH3 multiple domains 1 | | Authors: | Ohashi, W, Hirota, H, Nagashima, T, Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-26 | | Release date: | 2006-10-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RSGI RUH-061, a SH3 domain from human
to be published
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2DMO
 | | Refined solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) | | Descriptor: | Neutrophil cytosol factor 2 | | Authors: | Tochio, N, Chikayama, E, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-22 | | Release date: | 2006-05-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2)
To be Published
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2GQI
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2DL8
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2DL5
 | | Solution structure of the first SH3 domain of human KIAA0769 protein | | Descriptor: | KIAA0769 protein | | Authors: | Qin, X.R, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-17 | | Release date: | 2006-10-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first SH3 domain of human KIAA0769 protein
To be published
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