1BAJ
 
 | | HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN | | Descriptor: | GAG POLYPROTEIN | | Authors: | Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P. | | Deposit date: | 1998-04-17 | | Release date: | 1998-10-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
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6WY7
 | | CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-41 A.K.A 7-[1-phenyl-3-({4-phenylbicyclo[2.2.2]octan-1-yl}amino)propyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-{(1R)-1-phenyl-3-[(4-phenylbicyclo[2.2.2]octan-1-yl)amino]propyl}-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, CALCIUM ION, ... | | Authors: | Khan, J.A. | | Deposit date: | 2020-05-12 | | Release date: | 2020-10-14 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.
Bioorg.Med.Chem., 28, 2020
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6H5L
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7AP7
 | | Structure of the W64R amyloidogenic variant of human lysozyme | | Descriptor: | Lysozyme C, SULFATE ION | | Authors: | Vettore, N, Herman, R, Kerff, F, Charlier, P, Sauvage, E, Brans, A, Morray, J, Dobson, C, Kumita, J, Dumoulin, M. | | Deposit date: | 2020-10-16 | | Release date: | 2021-08-25 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme.
Biophys.Chem., 271, 2021
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6OMW
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7U1H
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7ANY
 | | Structure of the Laspartomycin C Friulimicin-like mutant in complex with Geranyl phosphate | | Descriptor: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Zeronian, M.R, Pearce, N.M, Lutz, M, Wood, T.M, Martin, N.I, Janssen, B.J.C. | | Deposit date: | 2020-10-13 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.135 Å) | | Cite: | Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures
Chem Sci, 13, 2022
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7QZR
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6VU0
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6V9K
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4WU0
 | | Structural Analysis of C. acetobutylicum ATCC 824 Glycoside Hydrolase From Family 105 | | Descriptor: | Similar to yteR (Bacilus subtilis) | | Authors: | Germane, K.L, Servinsky, M.D, Gerlach, E.S, Sund, C.J, Hurley, M.M. | | Deposit date: | 2014-10-30 | | Release date: | 2015-07-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of Clostridium acetobutylicum ATCC 824 glycoside hydrolase from CAZy family GH105.
Acta Crystallogr.,Sect.F, 71, 2015
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8IUG
 | | Cryo-EM structure of the RC-LH core complex from roseiflexus castenholzii | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... | | Authors: | Wang, G.-L, Qi, C.-H, Yu, L.-J. | | Deposit date: | 2023-03-24 | | Release date: | 2023-11-22 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes.
J.Biol.Chem., 299, 2023
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8IUN
 | | Cryo-EM structure of the CRT-LESS RC-LH core complex from roseiflexus castenholzii | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... | | Authors: | Wang, G.-L, Qi, C.-H, Yu, L.-J. | | Deposit date: | 2023-03-24 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes.
J.Biol.Chem., 299, 2023
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6WYD
 | | CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-12 (AKA; 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyrid | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, CALCIUM ION, ... | | Authors: | Khan, J.A. | | Deposit date: | 2020-05-12 | | Release date: | 2020-10-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.
Bioorg.Med.Chem., 28, 2020
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7XT1
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1UTA
 | | Solution structure of the C-terminal RNP domain from the divisome protein FtsN | | Descriptor: | CELL DIVISION PROTEIN FTSN | | Authors: | Yang, J.-C, van den Ent, F, Neuhaus, D, Brevier, J, Lowe, J. | | Deposit date: | 2003-12-04 | | Release date: | 2004-09-24 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure and Domain Architecture of the Divisome Protein Ftsn
Mol.Microbiol., 52, 2004
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8X0H
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate, Rcc conformation | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0E
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with agonist and PAM, W785A mutant | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0F
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and PAM VU29 | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0B
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with Quisqualate and VU0424465 | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0C
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and VU0424465, conformer 1 | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0G
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate, Acc conformation (purified with PAM VU0409551 but not modelled) | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | | Authors: | Vinothkumar, K.R, Lebon, G, Cannone, G. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8X0D
 | | Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and VU0424465, conformer 2 | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | | Authors: | Lebon, G, Cannone, G, Vinothkumar, K.R. | | Deposit date: | 2023-11-04 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Conformational diversity in class C GPCR positive allosteric modulation.
Nat Commun, 16, 2025
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8IEI
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7P4O
 | | Crystal structure of Autotaxin and 9(R)-delta6a,10a-THC | | Descriptor: | (9~{R},10~{a}~{S})-6,6,9-trimethyl-3-pentyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, ... | | Authors: | Eymery, M.C, McCarthy, A.A, Hausmann, J. | | Deposit date: | 2021-07-12 | | Release date: | 2022-12-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Linking medicinal cannabis to autotaxin-lysophosphatidic acid signaling.
Life Sci Alliance, 6, 2023
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