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4ZQT	Crystal structure of PfA-M1 with virtual ligand inhibitor Descriptor: (2R)-2-{[(R)-[(R)-amino(phenyl)methyl](hydroxy)phosphoryl]methyl}-4-methylpentanoic acid, GLYCEROL, M1 family aminopeptidase, ... Authors: Ruggeri, C, Drinkwater, N, McGowan, S. Deposit date: 2015-05-11 Release date: 2015-10-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening. Plos One, 10, 2015
4Z7I	Crystal structure of insulin regulated aminopeptidase in complex with ligand Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DG025 transition-state analogue enzyme inhibitor, ... Authors: Mpakali, A, Saridakis, E, Harlos, K, Zhao, Y, Stratikos, E. Deposit date: 2015-04-07 Release date: 2015-08-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing. J Immunol., 195, 2015
4ZW5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9f Descriptor: M1 family aminopeptidase, MAGNESIUM ION, ZINC ION, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10q Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-20 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4XO4	Crystal Structure of E. coli Aminopeptidase N in complex with L-Methionine Descriptor: Aminopeptidase N, GLYCEROL, MALONATE ION, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-16 Release date: 2016-01-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Methionine To Be Published
4ZW6	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9q Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZW3	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9b Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX4	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10o Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-20 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZW7	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9m Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
5AB0	Crystal structure of aminopeptidase ERAP2 with ligand Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Mpakali, A, Giastas, P, Saridakis, E, Stratikos, E. Deposit date: 2015-07-31 Release date: 2015-09-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2. J.Biol.Chem., 290, 2015
4ZW8	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9r Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX6	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10s Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-20 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016

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