1ZMI
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![BU of 1zmi by Molmil](/molmil-images/mine/1zmi) | Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group ) | Descriptor: | GLYCEROL, Neutrophil defensin 2, SULFATE ION | Authors: | Lubkowski, J, Prahl, A, Lu, W. | Deposit date: | 2005-05-10 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280, 2005
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1ZMJ
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![BU of 1zmj by Molmil](/molmil-images/mine/1zmj) | Crystal Structure of the Catalytic Domain of Factor XI in complex with 4-(guanidinomethyl)-phenylboronic acid | Descriptor: | (R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)BENZYL)GUANIDINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coagulation factor XI, ... | Authors: | Lazarova, T.I, Jin, L, Rynkiewicz, M.J, Gorga, J.C, Bibbins, F, Meyers, H.V, Babine, R.E, Strickler, J.E. | Deposit date: | 2005-05-10 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa. Bioorg.Med.Chem.Lett., 16, 2006
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1ZMK
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![BU of 1zmk by Molmil](/molmil-images/mine/1zmk) | Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group | Descriptor: | CHLORIDE ION, GLYCEROL, Neutrophil defensin 2 | Authors: | Lubkowski, J, Prahl, A, Lu, W. | Deposit date: | 2005-05-10 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280, 2005
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1ZML
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![BU of 1zml by Molmil](/molmil-images/mine/1zml) | Crystal Structure of the Catalytic Domain of Factor XI in complex with (R)-1-(4-(4-(hydroxymethyl)-1,3,2-dioxaborolan-2-yl)phenethyl)guanidine | Descriptor: | (R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)PHENETHYL)GUANIDINE, BICARBONATE ION, Coagulation factor XI, ... | Authors: | Lazarova, T.I, Jin, L, Rynkiewicz, M.J, Gorga, J.C, Bibbins, F, Meyers, H.V, Babine, R.E, Strickler, J.E. | Deposit date: | 2005-05-10 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa. Bioorg.Med.Chem.Lett., 16, 2006
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1ZMM
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1ZMN
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![BU of 1zmn by Molmil](/molmil-images/mine/1zmn) | Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with (R)-1-(4-(4-(hydroxymethyl)-1,3,2-dioxaborolan-2-yl)phenyl)guanidine | Descriptor: | (R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)PHENYL)GUANIDINE, Coagulation factor XI, SULFATE ION | Authors: | Lazarova, T.I, Jin, L, Rynkiewicz, M.J, Gorga, J.C, Bibbins, F, Meyers, H.V, Babine, R.E, Strickler, J.E. | Deposit date: | 2005-05-10 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa. Bioorg.Med.Chem.Lett., 16, 2006
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1ZMO
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![BU of 1zmo by Molmil](/molmil-images/mine/1zmo) | Apo structure of haloalcohol dehalogenase HheA of Arthrobacter sp. AD2 | Descriptor: | halohydrin dehalogenase | Authors: | de Jong, R.M, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-05-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J.Bacteriol., 188, 2006
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1ZMP
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![BU of 1zmp by Molmil](/molmil-images/mine/1zmp) | Crystal structure of human defensin-5 | Descriptor: | CHLORIDE ION, Defensin 5, GLYCEROL, ... | Authors: | Lubkowski, J, Szyk, A, Lu, W. | Deposit date: | 2005-05-10 | Release date: | 2006-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6. Protein Sci., 15, 2006
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1ZMQ
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![BU of 1zmq by Molmil](/molmil-images/mine/1zmq) | Crystal structure of human alpha-defensin-6 | Descriptor: | CHLORIDE ION, Defensin 6 | Authors: | Lubkowski, J, Szyk, A, Lu, W. | Deposit date: | 2005-05-10 | Release date: | 2006-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6. Protein Sci., 15, 2006
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1ZMR
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![BU of 1zmr by Molmil](/molmil-images/mine/1zmr) | Crystal Structure of the E. coli Phosphoglycerate Kinase | Descriptor: | CALCIUM ION, Phosphoglycerate kinase | Authors: | Marqusee, S. | Deposit date: | 2005-05-10 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability. J.Mol.Biol., 368, 2007
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1ZMS
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![BU of 1zms by Molmil](/molmil-images/mine/1zms) | LMP1 Protein binds to TRAF3 as a structural CD40 | Descriptor: | Latent membrane protein 1, TNF receptor associated factor 3 | Authors: | Wu, S.D, Xie, P, Welsh, K, Li, C, Ni, C.-Z, Zhu, X, Reed, J.C, Satterthwait, A.C, Bishop, G.A, Ely, K.R. | Deposit date: | 2005-05-10 | Release date: | 2005-07-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | LMP1 protein from the Epstein Barr virus is a structural CD40 decoy in B lymphocytes fro binding to TRAF3 J.Biol.Chem., 39, 2005
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1ZMT
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![BU of 1zmt by Molmil](/molmil-images/mine/1zmt) | Structure of haloalcohol dehalogenase HheC of Agrobacterium radiobacter AD1 in complex with (R)-para-nitro styrene oxide, with a water molecule in the halide-binding site | Descriptor: | (R)-PARA-NITROSTYRENE OXIDE, Haloalcohol dehalogenase HheC | Authors: | de Jong, R.M, Tiesinga, J.J.W, Villa, A, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-05-10 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for the Enantioselectivity of an Epoxide Ring Opening Reaction Catalyzed by Halo Alcohol Dehalogenase HheC. J.Am.Chem.Soc., 127, 2005
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1ZMU
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1ZMV
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![BU of 1zmv by Molmil](/molmil-images/mine/1zmv) | |
1ZMW
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1ZMX
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![BU of 1zmx by Molmil](/molmil-images/mine/1zmx) | Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine | Descriptor: | Deoxynucleoside kinase, SULFATE ION, THYMIDINE | Authors: | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | Deposit date: | 2005-05-11 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D. Febs J., 272, 2005
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1ZMY
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![BU of 1zmy by Molmil](/molmil-images/mine/1zmy) | cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | Descriptor: | Antibody cabbcII-10:lys3, Lysozyme C | Authors: | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | Deposit date: | 2005-05-11 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies J.Mol.Biol., 352, 2005
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1ZMZ
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![BU of 1zmz by Molmil](/molmil-images/mine/1zmz) | Solution structure of the N-terminal domain (M1-S98) of human centrin 2 | Descriptor: | Centrin-2 | Authors: | Yang, A, Miron, S, Duchambon, P, Assairi, L, Blouquit, Y, Craescu, C.T. | Deposit date: | 2005-05-11 | Release date: | 2006-04-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The N-terminal domain of human centrin 2 has a closed structure, binds calcium with a very low affinity, and plays a role in the protein self-assembly Biochemistry, 45, 2006
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1ZN0
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![BU of 1zn0 by Molmil](/molmil-images/mine/1zn0) | Coordinates of RRF and EF-G fitted into Cryo-EM map of the 50S subunit bound with both EF-G (GDPNP) and RRF | Descriptor: | 16S RIBOSOMAL RNA, ELONGATION FACTOR G, Ribosome recycling factor | Authors: | Gao, N, Zavialov, A.V, Li, W, Sengupta, J, Valle, M, Gursky, R.P, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (15.5 Å) | Cite: | Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol.Cell, 18, 2005
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1ZN1
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![BU of 1zn1 by Molmil](/molmil-images/mine/1zn1) | Coordinates of RRF fitted into Cryo-EM map of the 70S post-termination complex | Descriptor: | 30S ribosomal protein S12, Ribosome recycling factor, ribosomal 16S RNA, ... | Authors: | Gao, N, Zavialov, A.V, Li, W, Sengupta, J, Valle, M, Gursky, R.P, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (14.1 Å) | Cite: | Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol.Cell, 18, 2005
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1ZN2
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![BU of 1zn2 by Molmil](/molmil-images/mine/1zn2) | Low Resolution Structure of Response Regulator StyR | Descriptor: | MAGNESIUM ION, response regulatory protein | Authors: | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | Deposit date: | 2005-05-11 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism. STRUCTURE, 13, 2005
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1ZN3
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![BU of 1zn3 by Molmil](/molmil-images/mine/1zn3) | Crystal structure of Glu335Ala mutant of Clostridium botulinum neurotoxin type E | Descriptor: | CHLORIDE ION, ZINC ION, botulinum neurotoxin type E | Authors: | Agarwal, R, Binz, T, Swaminathan, S. | Deposit date: | 2005-05-11 | Release date: | 2005-07-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme. Biochemistry, 44, 2005
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1ZN5
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1ZN6
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![BU of 1zn6 by Molmil](/molmil-images/mine/1zn6) | X-ray Crystal Structure of Protein Q7WLM8 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium Target BoR19. | Descriptor: | SULFATE ION, phage-related conserved hypothetical protein | Authors: | Kuzin, A.P, Yong, W, Vorobiev, S.M, Xiao, R, Ma, L.-C, Acton, T, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-05-11 | Release date: | 2005-05-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Novel structure of the hypothetical protein Q7WLM8 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium target BoR19. To be Published
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1ZN7
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![BU of 1zn7 by Molmil](/molmil-images/mine/1zn7) | Human Adenine Phosphoribosyltransferase Complexed with PRPP, ADE and R5P | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, ADENINE, ... | Authors: | Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. | Deposit date: | 2005-05-11 | Release date: | 2006-04-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism J.Biomol.Struct.Dyn., 25, 2008
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