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5F9B
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BU of 5f9b by Molmil
X-ray crystal structure of PPARgamma in the complex with caulophyllogenin
Descriptor: Caulophyllogenin, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2015-12-09
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Screening of saponins and sapogenins from Medicago species as potential PPAR gamma agonists and X-ray structure of the complex PPAR gamma /caulophyllogenin.
Sci Rep, 6, 2016
7NKE
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BU of 7nke by Molmil
Crystal structure of human RXRalpha ligand binding domain in complex with 2,4-di-tert-butylphenol and a coactivator fragment
Descriptor: 2,4-di~{tert}-butylphenol, FORMIC ACID, Nuclear receptor coactivator 2, ...
Authors:Carivenc, C, Bourguet, W.
Deposit date:2021-02-17
Release date:2022-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors.
Endocrinology, 164, 2023
5VHO
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BU of 5vho by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
Authors:Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
3CCS
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BU of 3ccs by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482A
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-26
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3AJH
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BU of 3ajh by Molmil
Crystal structure of PcyA V225D-biliverdin XIII alpha complex
Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methy l]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Phycocyanobilin:ferredoxin oxidoreductase
Authors:Wada, K, Hagiwara, Y, Fukuyama, K.
Deposit date:2010-06-05
Release date:2011-03-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:One residue substitution in PcyA leads to unexpected changes in tetrapyrrole substrate binding.
Biochem.Biophys.Res.Commun., 402, 2010
3ALW
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BU of 3alw by Molmil
Crystal structure of the measles virus hemagglutinin bound to its cellular receptor SLAM (Form I, MV-H-SLAM(N102H/R108Y) fusion)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, CDw150
Authors:Hashiguchi, T, Ose, T, Kubota, M, Maita, N, Kamishikiryo, J, Maenaka, K, Yanagi, Y.
Deposit date:2010-08-09
Release date:2011-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure of the measles virus hemagglutinin bound to its cellular receptor SLAM
Nat.Struct.Mol.Biol., 18, 2011
5H6R
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BU of 5h6r by Molmil
Crystal structure of LSD1-CoREST in complex with peptide 13
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
Authors:Kkuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T.
Deposit date:2016-11-14
Release date:2017-04-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
3H7I
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BU of 3h7i by Molmil
Structure of the metal-free D132N T4 RNase H
Descriptor: Ribonuclease H, SULFATE ION
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-27
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
To be Published
3ADE
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BU of 3ade by Molmil
Crystal Structure of Keap1 in Complex with Sequestosome-1/p62
Descriptor: Kelch-like ECH-associated protein 1, SULFATE ION, Sequestosome-1
Authors:Kurokawa, H, Yamamoto, M.
Deposit date:2010-01-19
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nat.Cell Biol., 12, 2010
3CRG
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BU of 3crg by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala
Descriptor: FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ...
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-07
Release date:2009-02-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CME
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BU of 3cme by Molmil
The Structure of CA and CCA-PHE-CAP-BIO Bound to the Large Ribosomal Subunit of Haloarcula Marismortui
Descriptor: 50S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Simonovic, M, Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3H8J
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BU of 3h8j by Molmil
Native T4 RNase H in the absence of divalent metal ions
Descriptor: Ribonuclease H, SODIUM ION, SULFATE ION
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-29
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
To be Published
3H8W
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BU of 3h8w by Molmil
Structure of D132N T4 RNase H in the presence of divalent magnesium
Descriptor: Ribonuclease H
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-29
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
TO BE PUBLISHED
3H8S
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BU of 3h8s by Molmil
Structure of D19N T4 RNase H in the presence of divalent magnesium
Descriptor: MAGNESIUM ION, Ribonuclease H
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-29
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
To be Published
3CKC
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BU of 3ckc by Molmil
B. thetaiotaomicron SusD
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Koropatkin, N.M, Martens, E.C, Gordon, J.I, Smith, T.J.
Deposit date:2008-03-14
Release date:2008-04-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices.
Structure, 16, 2008
3CVI
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BU of 3cvi by Molmil
How TCR-like antibody recognizes MHC-bound peptide
Descriptor: 25-D1.16 Heavy chain, 25-D1.16 Light chain
Authors:Mareeva, T, Martinez-Hackert, E, Sykulev, Y.
Deposit date:2008-04-18
Release date:2008-09-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide
J.Biol.Chem., 283, 2008
2ZH6
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BU of 2zh6 by Molmil
Complex structure of AFCCA with tRNAminiDCU and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ...
Authors:Toh, Y, Tomita, K.
Deposit date:2008-02-01
Release date:2008-08-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
2Z47
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BU of 2z47 by Molmil
The Y66L mutant of tetraheme cytochrome c3 from Desulfovibrio Vulgaris Miyazaki F
Descriptor: Cytochrome c3, HEME C
Authors:Higuchi, Y, Komori, H.
Deposit date:2007-06-13
Release date:2008-06-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of Noncoordinated Aromatic Residue Mutants in Tetraheme Cytochrome c3 from Desulfovibrio vulgaris Miyazaki F
To be Published
2ZJU
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BU of 2zju by Molmil
Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein (Ls-AChBP) Complexed with Imidacloprid
Descriptor: (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, Acetylcholine-binding protein
Authors:Okajima, T, Ihara, M, Yamashita, A, Oda, T, Morimoto, T, Matsuda, K.
Deposit date:2008-03-10
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin
Invert.Neurosci., 8, 2008
1PE0
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BU of 1pe0 by Molmil
Crystal structure of the K130R mutant of human DJ-1
Descriptor: DJ-1
Authors:Tao, X, Tong, L.
Deposit date:2003-05-20
Release date:2003-06-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
2ZM6
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BU of 2zm6 by Molmil
Crystal structure of the Thermus thermophilus 30S ribosomal subunit
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kaminishi, T, Wang, H, Kawazoe, M, Ishii, R, Schluenzen, F, Hanawa-Suetsugu, K, Wilson, D.N, Nomura, M, Takemoto, C, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-04-11
Release date:2009-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the Thermus thermophilus 30S ribosomal subunit
To be Published
3CMA
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BU of 3cma by Molmil
The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Simonovic, M, Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CKB
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BU of 3ckb by Molmil
B. thetaiotaomicron SusD with maltotriose
Descriptor: CALCIUM ION, SusD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Koropatkin, N.M, Martens, E.C, Gordon, J.I, Smith, T.J.
Deposit date:2008-03-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices.
Structure, 16, 2008
3CR1
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BU of 3cr1 by Molmil
crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2
Descriptor: MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'), ...
Authors:Salter, J.D, Wedekind, J.E.
Deposit date:2008-04-04
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme.
Rna, 14, 2008
3CQA
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BU of 3cqa by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-02
Release date:2009-04-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009

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数据于2024-10-16公开中

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