8OIP
 
 | 28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | Descriptor: | 12S rRNA, 28S ribosomal protein S15, mitochondrial, ... | Authors: | Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. | Deposit date: | 2023-03-23 | Release date: | 2023-05-24 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
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6BV5
 
 | Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana after 45-minute soak with juglone | Descriptor: | 5-hydroxynaphthalene-1,4-dione, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Karasik, A, Wu, N, Fierke, C.A, Koutmos, M. | Deposit date: | 2017-12-12 | Release date: | 2019-06-12 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Inhibition of protein-only RNase P with Gambogic acid and Juglone To Be Published
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2TRX
 
 | CRYSTAL STRUCTURE OF THIOREDOXIN FROM ESCHERICHIA COLI AT 1.68 ANGSTROMS RESOLUTION | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, THIOREDOXIN | Authors: | Katti, S.K, Lemaster, D.M, Eklund, H. | Deposit date: | 1990-03-19 | Release date: | 1991-10-15 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structure of thioredoxin from Escherichia coli at 1.68 A resolution. J.Mol.Biol., 212, 1990
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1XY5
 
 | NMR strcutre of sst1-selective somatostatin (SRIF) analog 1 | Descriptor: | SST1-selective somatosatin analog | Authors: | Grace, C.R.R, Durrer, L, Koerber, S.C, Erchegyi, J, Reubi, J.C, Rivier, J.E, Riek, R. | Deposit date: | 2004-11-09 | Release date: | 2005-02-15 | Last modified: | 2025-03-26 | Method: | SOLUTION NMR | Cite: | Somatostatin receptor 1 selective analogues: 4. Three-dimensional consensus structure by NMR J.Med.Chem., 48, 2005
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7G9T
 
 | PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z18618496 | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Serine protease NS3, ... | Authors: | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | Deposit date: | 2023-07-03 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | PanDDA analysis group deposition To Be Published
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5A7L
 
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7G9Y
 
 | PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z2678251369 | Descriptor: | 1,2-ETHANEDIOL, 2-tert-butyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, ... | Authors: | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | Deposit date: | 2023-07-03 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | PanDDA analysis group deposition To Be Published
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3K50
 
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7CI7
 
 | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | Descriptor: | (2R,3R)-2-azanyl-1-[4-[[4-[2-[4-(hydroxymethyl)phenyl]ethynyl]phenyl]methyl]piperidin-1-yl]-4-methylsulfonyl-3-oxidanyl-butan-1-one, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | Authors: | Mima, M, Baker, L.M, Surgenor, A, Robertson, A. | Deposit date: | 2020-07-07 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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3JTX
 
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4YCT
 
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7CI8
 
 | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | Descriptor: | (1S)-1-[1-[(5-phenyl-1,2-oxazol-3-yl)methyl]imidazol-2-yl]ethanol, MAGNESIUM ION, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Mima, M, Baker, L.M, Surgenor, A, Robertson, A. | Deposit date: | 2020-07-07 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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9MIA
 
 | 206-3G08 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 206-3G08 heavy chain Fv, ... | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | Deposit date: | 2024-12-12 | Release date: | 2025-05-21 | Last modified: | 2025-08-13 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans. Science, 389, 2025
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5H4E
 
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5VCZ
 
 | CRYSTAL STRUCTURE OF HUMAN MYT1 KINASE DOMAIN IN COMPLEX WITH Bosutinib isomer | Descriptor: | 1,2-ETHANEDIOL, 4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
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4YMZ
 
 | DHAP bound Leptospira Interrogans Triosephosphate Isomerase (LiTIM) | Descriptor: | 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, SULFATE ION, ... | Authors: | Pareek, V, Balaram, P, Murthy, M.R.N. | Deposit date: | 2015-03-08 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme Chembiochem, 17, 2016
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4MSO
 
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6C0D
 
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5YLN
 
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1LAE
 
 | Solution Structure of the DNA 13-mer Hairpin CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct at the Seventh Position | Descriptor: | 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3' | Authors: | Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P. | Deposit date: | 2002-03-28 | Release date: | 2002-04-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the 1,N(2)-propanodeoxyguanosine adduct in a three-base DNA hairpin loop derived from a palindrome in the Salmonella typhimurium hisD3052 gene. Chem.Res.Toxicol., 15, 2002
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6BZ3
 
 | Complex structure of FAK FAT domain and DCC P3 motif | Descriptor: | CALCIUM ION, Focal adhesion kinase 1, Netrin receptor DCC | Authors: | Xu, S, Wang, J.-H. | Deposit date: | 2017-12-22 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction. Cell Discov, 4, 2018
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4Y5Q
 
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4JHS
 
 | Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1 | Descriptor: | Beta-2-glycoprotein 1, SULFATE ION | Authors: | Bonanno, J.B, Toro, R, Gizzi, A, Chan, M.K, Garrett-Thomson, S.C, Patel, H, Lim, S, Matikainen, B, Celikgil, A, Garforth, S, Hillerich, B, Seidel, R, Rand, J.H, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2013-03-05 | Release date: | 2013-04-24 | Last modified: | 2024-11-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1 To be Published
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1T9D
 
 | Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide, Metsulfuron methyl | Descriptor: | 2,5-DIMETHYL-PYRIMIDIN-4-YLAMINE, Acetolactate synthase, mitochondrial, ... | Authors: | McCourt, J.A, Pang, S.S, Guddat, L.W, Duggleby, R.G. | Deposit date: | 2004-05-16 | Release date: | 2004-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry, 44, 2005
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7AJE
 
 | bovine ATP synthase dimer state2:state1 | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | Authors: | Spikes, T.E, Montgomery, M.G, Walker, J.E. | Deposit date: | 2020-09-29 | Release date: | 2021-02-03 | Last modified: | 2025-04-09 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes. Proc.Natl.Acad.Sci.USA, 118, 2021
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