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8VXC
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BU of 8vxc by Molmil
Structure of HamB-DNA complex, conformation 2, from the Escherichia coli Hachiman defense system
Descriptor: DNA (40-MER), HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-04
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8KGR
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BU of 8kgr by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (32-MER), DNA (33-MER), DNA topoisomerase 2, ...
Authors:Cong, J, Xin, U, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
6VAE
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BU of 6vae by Molmil
Mono-ubiquitinated Fanconi Anemia ID complex bound to ICL DNA
Descriptor: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
Authors:Pavletich, N.P.
Deposit date:2019-12-17
Release date:2020-03-18
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
8TLQ
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BU of 8tlq by Molmil
Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
Authors:Malik, R, Aggarwal, A.K.
Deposit date:2023-07-27
Release date:2024-05-15
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 31, 2024
8QHM
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BU of 8qhm by Molmil
DNA mimic Foldamer with sticky ends
Descriptor: DNA mimic Foldamer
Authors:Deepak, D, Loos, M, Huc, I.
Deposit date:2023-09-08
Release date:2023-10-11
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Enhancing the Features of DNA Mimic Foldamers for Structural Investigations.
Chemistry, 30, 2024
8KGQ
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BU of 8kgq by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (38-MER), DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
8KGN
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BU of 8kgn by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (38-MER), DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
8KGM
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BU of 8kgm by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (38-MER), DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
6NY2
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BU of 6ny2 by Molmil
CasX-gRNA-DNA(45bp) state I
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
5BNG
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BU of 5bng by Molmil
monomer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA
Descriptor: DNA (5'-D(P*AP*AP*TP*TP*AP*GP*CP*TP*GP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A-3'), ...
Authors:Morgunova, E, Jolma, A, Yin, Y, Nitta, K, Dave, K, Popov, A, Taipale, M, Enge, M, Kivioja, T, Taipale, J.
Deposit date:2015-05-26
Release date:2015-11-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:DNA-dependent formation of transcription factor pairs alters their binding specificity.
Nature, 527, 2015
6NY1
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BU of 6ny1 by Molmil
CasX-gRNA-DNA(30bp) State II
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
4Z3C
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BU of 4z3c by Molmil
Zinc finger region of human TET3 in complex with CpG DNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase, UNKNOWN ATOM OR ION, ...
Authors:Liu, K, Xu, C, Tempel, W, Dong, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-03-31
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 2017
6CBS
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BU of 6cbs by Molmil
DnaG Primase C-terminal domain complex with SSB C-terminal peptide
Descriptor: ACETIC ACID, DNA primase, single-stranded DNA-binding protein chimera, ...
Authors:Oakley, A.J, Lo, A.T.Y.
Deposit date:2018-02-05
Release date:2019-02-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:DnaG Primase C-terminal domain complex with SSB C-terminal peptide
To be Published
4P4P
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BU of 4p4p by Molmil
Crystal structure of Leishmania infantum polymerase beta: Nick complex
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(P*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ...
Authors:Mejia, E, Burak, M, Alonso, A, Larraga, V, Kunkel, T, Bebenek, K, Garcia-Diaz, M.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2973 Å)
Cite:Structures of the Leishmania infantum polymerase beta.
DNA Repair (Amst.), 18, 2014
3ULP
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BU of 3ulp by Molmil
Plasmodium falciparum SSB complex with ssDNA
Descriptor: DNA (35-MER), Single-strand binding protein
Authors:Antony, E, Lohman, T.M, Korolev, S.
Deposit date:2011-11-11
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Plasmodium falciparum SSB Tetramer Wraps Single-Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB.
J.Mol.Biol., 420, 2012
6CBT
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BU of 6cbt by Molmil
DnaG Primase C-terminal domain complex with SSB C-terminal peptide
Descriptor: ACETIC ACID, DNA primase, single-stranded DNA-binding protein chimera, ...
Authors:Oakley, A.J, Lo, A.T.Y.
Deposit date:2018-02-05
Release date:2019-02-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:DnaG Primase C-terminal domain complex with SSB C-terminal peptide
To be Published
1L8Q
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BU of 1l8q by Molmil
CRYSTAL STRUCTURE OF DNA REPLICATION INITIATION FACTOR
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosomal replication initiator protein dnaA, MAGNESIUM ION
Authors:Erzberger, J.P, Pirruccello, M.M, Berger, J.M.
Deposit date:2002-03-21
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation
Embo J., 21, 2002
2R5U
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BU of 2r5u by Molmil
Crystal structure of the N-terminal domain of DnaB helicase from Mycobacterium tuberculosis
Descriptor: GLYCEROL, Replicative DNA helicase
Authors:Biswas, T, Tsodikov, O.V.
Deposit date:2007-09-04
Release date:2008-05-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hexameric ring structure of the N-terminal domain of Mycobacterium tuberculosis DnaB helicase.
Febs J., 275, 2008
6GN4
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BU of 6gn4 by Molmil
tc-DNA/tc-DNA duplex
Descriptor: Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), Tc-DNA (5'-D(*(TCS)P*(TTK)P*(TCY)P*(TCY)P*(TCS)P*(TCJ)P*(TCJ)P*(TCS)P*(TCY)P*(TCS))-3')
Authors:Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
Deposit date:2018-05-29
Release date:2018-06-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
3GXV
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BU of 3gxv by Molmil
Three-dimensional structure of N-terminal domain of DnaB Helicase from Helicobacter pylori and its interactions with primase
Descriptor: Replicative DNA helicase
Authors:Kashav, T, Nitharwal, R, Syed, A.A, Gabdoulkhakov, A, Saenger, W, Dhar, K.S, Gourinath, S.
Deposit date:2009-04-03
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of N-terminal domain of DnaB helicase and helicase-primase interactions in Helicobacter pylori
Plos One, 4, 2009
7Z8S
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BU of 7z8s by Molmil
Mot1:TBP:DNA - post hydrolysis state
Descriptor: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein
Authors:Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P.
Deposit date:2022-03-18
Release date:2023-03-29
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
7Z7N
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BU of 7z7n by Molmil
Mot1E1434Q:TBP:DNA - substrate recognition state
Descriptor: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein
Authors:Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P.
Deposit date:2022-03-16
Release date:2023-03-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
7ZB5
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BU of 7zb5 by Molmil
Mot1(1-1836):TBP:DNA - post-hydrolysis complex dimer
Descriptor: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein
Authors:Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P.
Deposit date:2022-03-23
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
6GPI
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BU of 6gpi by Molmil
Tc-DNA/DNA duplex
Descriptor: DNA (5'-D(*GP*TP*AP*AP*GP*CP*CP*GP*AP*G)-3'), tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
Authors:Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
Deposit date:2018-06-05
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
8G0H
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BU of 8g0h by Molmil
Human PARP1 deltaV687-E688 bound to UKTT5 (compound 10) and to a DNA double strand break.
Descriptor: 2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide, DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*CP*G)-3'), ...
Authors:Rouleau-Turcotte, E, Pascal, J.M.
Deposit date:2023-01-31
Release date:2024-02-07
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Biochem.J., 481, 2024

225681

数据于2024-10-02公开中

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