1RXK
 
 | | crystal structure of streptavidin mutant (M3) a combination of M1+M2 | | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin | | Authors: | Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-12-18 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural elements responsible for conversion of streptavidin to a pseudoenzyme.
Proc.Natl.Acad.Sci.USA, 101, 2004
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5F2B
 | | Expanding Nature's Catalytic Repertoire -Directed Evolution of an Artificial Metalloenzyme for In Vivo Metathesis | | Descriptor: | SULFATE ION, Streptavidin, [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium | | Authors: | Heinisch, T, Jeschek, M, Reuter, R, Trindler, C, Panke, S, Ward, T.R. | | Deposit date: | 2015-12-01 | | Release date: | 2016-08-31 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Directed evolution of artificial metalloenzymes for in vivo metathesis.
Nature, 537, 2016
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7EK8
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6AUO
 | | Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112F | | Descriptor: | N-biotin-C-Co4(mu3-O)4(Py)3(H2O)4-beta-alanine, Streptavidin | | Authors: | Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S. | | Deposit date: | 2017-09-01 | | Release date: | 2018-02-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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1KL3
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7KBY
 | | Artificial Metalloproteins with Dinuclear Iron Centers | | Descriptor: | ACETATE ION, CYANIDE ION, Streptavidin, ... | | Authors: | Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S. | | Deposit date: | 2020-10-03 | | Release date: | 2021-02-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
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7EFC
 | | 1.70 A cryo-EM structure of streptavidin | | Descriptor: | BIOTIN, Streptavidin | | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | | Deposit date: | 2021-03-21 | | Release date: | 2021-04-28 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (1.7 Å) | | Cite: | 1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose)
To Be Published
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6VOB
 | | Artificial Metalloproteins with Dinuclear Iron Centers | | Descriptor: | ACETATE ION, AZIDE ION, Streptavidin, ... | | Authors: | Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S. | | Deposit date: | 2020-01-30 | | Release date: | 2021-02-03 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
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5K67
 | | Designed Artificial Cupredoxins | | Descriptor: | GLYCEROL, Streptavidin, [CuII(biot-pr-dpea)]2+ | | Authors: | Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S. | | Deposit date: | 2016-05-24 | | Release date: | 2016-07-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Modular Artificial Cupredoxins.
J.Am.Chem.Soc., 138, 2016
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1NQM
 | | Structure of Savm-W120K, streptavidin mutant | | Descriptor: | BIOTIN, Streptavidin | | Authors: | Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-01-22 | | Release date: | 2003-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
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6FRY
 | | Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology | | Descriptor: | Streptavidin, [CoBr(appy)-Biot]Br | | Authors: | Keller, S, Probst, B, Heinisch, T, Alberto, R, Ward, T.R. | | Deposit date: | 2018-02-16 | | Release date: | 2019-03-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology
Helv.Chim.Acta, 101, 2018
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1RST
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1RSU
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1SWH
 | | CORE-STREPTAVIDIN MUTANT W79F AT PH 4.5 | | Descriptor: | CORE-STREPTAVIDIN | | Authors: | Freitag, S, Le Trong, I, Chilkoti, A, Klumb, L.A, Stayton, P.S, Stenkamp, R.E. | | Deposit date: | 1998-01-27 | | Release date: | 1999-02-09 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
J.Mol.Biol., 279, 1998
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1KL4
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3WZQ
 | | Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with iminobiotin long tail (IMNtail) at 1.7 A resolution | | Descriptor: | 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, HEXAETHYLENE GLYCOL, Streptavidin | | Authors: | Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Tsumoto, K, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A. | | Deposit date: | 2014-10-01 | | Release date: | 2015-02-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J.Biochem., 157, 2015
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1HQQ
 | | MINIPROTEIN MP-2 (M9A) COMPLEX WITH STREPTAVIDIN | | Descriptor: | MP-2, STREPTAVIDIN | | Authors: | Yang, H.W, Liu, D.Q, Fan, X, White, M.A, Fox, R.O. | | Deposit date: | 2000-12-19 | | Release date: | 2003-09-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Conformational Ensemble Analysis of Ligand Binding in Streptavidin Mini-protein Complexes
To be Published
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5WBC
 | | Designed Artificial Cupredoxins - WT | | Descriptor: | ACETATE ION, GLYCEROL, Streptavidin, ... | | Authors: | Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S. | | Deposit date: | 2017-06-28 | | Release date: | 2017-08-16 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Modular Artificial Cupredoxins.
J. Am. Chem. Soc., 138, 2016
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7ZOF
 | | Streptavidin Iron-Porphyrin | | Descriptor: | (2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-[[(5Z,10Z,14Z,19Z)-15-[[[(2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-sulfo-propanoyl]amino]methyl]-1,4,21,23-tetrahydroporphyrin-5-yl]methylamino]-3-oxidanylidene-propane-1-sulfonic acid, FE (III) ION, IMIDAZOLE, ... | | Authors: | Igareta, N.V, Ward, T.R. | | Deposit date: | 2022-04-25 | | Release date: | 2022-07-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Streptavidin Iron-Porphyrin
To Be Published
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1VWP
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6T32
 | | Streptavidin variants harbouring an artificial organocatalyst based cofactor | | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, Streptavidin | | Authors: | Lechner, H, Hocker, B. | | Deposit date: | 2019-10-10 | | Release date: | 2020-11-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*.
Chembiochem, 22, 2021
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4JO6
 | | Streptavidin complex with SBP-Tag | | Descriptor: | SBP-Tag, Streptavidin | | Authors: | Barrette-Ng, I.H, Wu, S.C, Tjia, W.M, Wong, S.L, Ng, K.K.S. | | Deposit date: | 2013-03-17 | | Release date: | 2013-05-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The structure of the SBP-Tag-streptavidin complex reveals a novel helical scaffold bridging binding pockets on separate subunits
Acta Crystallogr.,Sect.D, 69, 2013
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1SLF
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1SLG
 | | STREPTAVIDIN, PH 5.6, BOUND TO PEPTIDE FCHPQNT | | Descriptor: | FCHPQNT, STREPTAVIDIN | | Authors: | Katz, B.A. | | Deposit date: | 1995-03-10 | | Release date: | 1996-04-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Binding to protein targets of peptidic leads discovered by phage display: crystal structures of streptavidin-bound linear and cyclic peptide ligands containing the HPQ sequence
Biochemistry, 34, 1995
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7EFD
 | | 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose) | | Descriptor: | BIOTIN, Streptavidin | | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | | Deposit date: | 2021-03-21 | | Release date: | 2021-04-28 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (1.77 Å) | | Cite: | 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose)
To Be Published
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