2MVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mvv by Molmil](/molmil-images/mine/2mvv) | Solution Structure of the 5-phenyl-3-oxo-pentyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | Descriptor: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide | Authors: | Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P. | Deposit date: | 2014-10-15 | Release date: | 2015-10-21 | Method: | SOLUTION NMR | Cite: | ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates To be Published
|
|
2N6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n6y by Molmil](/molmil-images/mine/2n6y) | |
2N5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n5h by Molmil](/molmil-images/mine/2n5h) | PltL-holo | Descriptor: | 4'-PHOSPHOPANTETHEINE, Peptidyl carrier protein PltL | Authors: | Jaremko, M.J, Lee, D.J, Burkart, M.D. | Deposit date: | 2015-07-17 | Release date: | 2015-09-16 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. J.Am.Chem.Soc., 137, 2015
|
|
2LML
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lml by Molmil](/molmil-images/mine/2lml) | Solution NMR structure of holo acyl carrier protein from geobacter Metallireducens refined with nh rdcs, Northeast Structural Genomics consortium target gmr141 | Descriptor: | 4'-PHOSPHOPANTETHEINE, Putative acyl carrier protein | Authors: | Ramelot, T.A, Smola, M.J, Lee, H, Zhao, L, Ciccosanti, C, Foote, E.L, Hamilton, K, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-12-05 | Release date: | 2012-01-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure of 4'-phosphopantetheine - GmACP3 from Geobacter metallireducens: a specialized acyl carrier protein with atypical structural features and a putative role in lipopolysaccharide biosynthesis. Biochemistry, 50, 2011
|
|
2LPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lpk by Molmil](/molmil-images/mine/2lpk) | Solution NMR of the specialized apo-acyl carrier protein (RPA2022) from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR324 | Descriptor: | Specialized acyl carrier protein | Authors: | Ramelot, T.A, Rossi, P, Yang, Y, Lee, H, Ertekin, A, Wang, H, Ciccosanti, C, Kohan, E, Maglaqui, M, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-14 | Release date: | 2012-02-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations. Biochemistry, 51, 2012
|
|
2LIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2liw by Molmil](/molmil-images/mine/2liw) | NMR structure of HMG-ACPI domain from CurA module from Lyngbya majuscula | Descriptor: | 3-HYDROXY-3-METHYL-GLUTARIC ACID, 4'-PHOSPHOPANTETHEINE, CurA | Authors: | Busche, A.E, Gottstein, D, Hein, C, Ripin, N, Pader, I, Tufar, P, Eisman, E.B, Gu, L, Walsh, C.T, Loehr, F, Sherman, D.H, Guntert, P, Dotsch, V. | Deposit date: | 2011-09-01 | Release date: | 2011-12-21 | Last modified: | 2012-03-14 | Method: | SOLUTION NMR | Cite: | Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase. Acs Chem.Biol., 7, 2012
|
|
2LOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lol by Molmil](/molmil-images/mine/2lol) | |
7B2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b2b by Molmil](/molmil-images/mine/7b2b) | Solution structure of a non-covalent extended docking domain complex of the Pax NRPS: PaxA T1-CDD/PaxB NDD | Descriptor: | Amino acid adenylation domain-containing protein, Peptide synthetase PaxA | Authors: | Watzel, J, Sarawi, S, Duchardt-Ferner, E, Bode, H.B, Woehnert, J. | Deposit date: | 2020-11-26 | Release date: | 2021-06-16 | Last modified: | 2024-07-03 | Method: | SOLUTION NMR | Cite: | Cooperation between a T Domain and a Minimal C-Terminal Docking Domain to Enable Specific Assembly in a Multiprotein NRPS. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
7WRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wrp by Molmil](/molmil-images/mine/7wrp) | Crystal Structure of pks13-ACP domain from Corynebacterium diphtheriae | Descriptor: | 4'-PHOSPHOPANTETHEINE, Polyketide synthase involved in mycolic acid biosynthesis | Authors: | Liu, X. | Deposit date: | 2022-01-27 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.794 Å) | Cite: | Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae. Biochem.Biophys.Res.Commun., 590, 2022
|
|
4DXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dxe by Molmil](/molmil-images/mine/4dxe) | 2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL | Descriptor: | Acyl carrier protein, MALONATE ION, acyl-carrier-protein synthase | Authors: | Halavaty, A.S, Minasov, G, Filippova, E.V, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-02-27 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | 2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL To be Published
|
|
3TEJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tej by Molmil](/molmil-images/mine/3tej) | |
8H6S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h6s by Molmil](/molmil-images/mine/8h6s) | Structure of acyltransferase VinK in complex with the loading acyl carrier protein of vicenistatin PKS | Descriptor: | MAGNESIUM ION, Malonyl-CoA-[acyl-carrier-protein] transacylase, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... | Authors: | Kawada, K, Miyanaga, A, Chisuga, T, Kudo, F, Eguchi, T. | Deposit date: | 2022-10-18 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Transient Interactions of Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase. Biochemistry, 62, 2023
|
|
7F2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f2r by Molmil](/molmil-images/mine/7f2r) | Crystal structure of VinK-VinL covalent complex formed with a pantetheineamide cross-linking probe | Descriptor: | Acyl-carrier-protein, Malonyl-CoA-[acyl-carrier-protein] transacylase, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide | Authors: | Miyanaga, A, Ouchi, R, Kudo, F, Eguchi, T. | Deposit date: | 2021-06-14 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Complex structure of the acyltransferase VinK and the carrier protein VinL with a pantetheine cross-linking probe. Acta Crystallogr.,Sect.F, 77, 2021
|
|
3NY7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ny7 by Molmil](/molmil-images/mine/3ny7) | STAS domain of YchM bound to ACP | Descriptor: | 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, Acyl carrier protein, GLYCEROL, ... | Authors: | Moraes, T.F, Reithmeier, R, Strynadka, N.C.S. | Deposit date: | 2010-07-14 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Structure of a SLC26 Anion Transporter STAS Domain in Complex with Acyl Carrier Protein: Implications for E. coli YchM in Fatty Acid Metabolism. Structure, 18, 2010
|
|
2XZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xz0 by Molmil](/molmil-images/mine/2xz0) | The Structure of the 2:1 (Partially Occupied) Complex Between Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) and Acyl Carrier Protein. | Descriptor: | 1,2-ETHANEDIOL, ACYL CARRIER PROTEIN 1, CHLOROPLASTIC, ... | Authors: | Moche, M, Guy, J.E, Whittle, E, Lengqvist, J, Shanklin, J, Lindqvist, Y. | Deposit date: | 2010-11-22 | Release date: | 2011-09-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Remote Control of Regioselectivity in Acyl-Acyl Carrier Protein-Desaturases. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2XZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xz1 by Molmil](/molmil-images/mine/2xz1) | The Structure of the 2:2 (Fully Occupied) Complex Between Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) and Acyl Carrier Protein. | Descriptor: | (2R)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide, ACYL CARRIER PROTEIN 1, CHLOROPLASTIC, ... | Authors: | Guy, J.E, Moche, M, Whittle, E, Lengqvist, J, Shanklin, J, Lindqvist, Y. | Deposit date: | 2010-11-22 | Release date: | 2011-09-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Remote Control of Regioselectivity in Acyl-Acyl Carrier Protein-Desaturases. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
6VTJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vtj by Molmil](/molmil-images/mine/6vtj) | |
4ZJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zjb by Molmil](/molmil-images/mine/4zjb) | Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori | Descriptor: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ... | Authors: | Zhang, L, Zhang, L, Shen, X, Jiang, H. | Deposit date: | 2015-04-29 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis. Cell Res., 26, 2016
|
|
6VTZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vtz by Molmil](/molmil-images/mine/6vtz) | |
5ZK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zk4 by Molmil](/molmil-images/mine/5zk4) | The structure of DSZS acyltransferase with carrier protein | Descriptor: | DisA protein, DisD protein, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... | Authors: | Miyanaga, A, Ouchi, R, Kudo, F, Eguchi, T. | Deposit date: | 2018-03-23 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis of protein-protein interactions between a trans-acting acyltransferase and acyl carrier protein in polyketide disorazole biosynthesis J. Am. Chem. Soc., 140, 2018
|
|
1F80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f80 by Molmil](/molmil-images/mine/1f80) | HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH HOLO-(ACYL CARRIER PROTEIN) | Descriptor: | ACYL CARRIER PROTEIN, HOLO-(ACYL CARRIER PROTEIN) SYNTHASE, SODIUM ION | Authors: | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | Deposit date: | 2000-06-28 | Release date: | 2001-06-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure Fold.Des., 8, 2000
|
|
4MRT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mrt by Molmil](/molmil-images/mine/4mrt) | Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | Descriptor: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | Authors: | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | Deposit date: | 2013-09-17 | Release date: | 2014-04-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
|
|
5CZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5czd by Molmil](/molmil-images/mine/5czd) | The complex structure of VinK with VinL | Descriptor: | 1,1'-ethane-1,2-diyldipyrrolidine-2,5-dione, 4'-PHOSPHOPANTETHEINE, Acyl-carrier-protein, ... | Authors: | Miyanaga, A, Iwasawa, S, Shinohara, Y, Kudo, F, Eguchi, T. | Deposit date: | 2015-07-31 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5EJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ejd by Molmil](/molmil-images/mine/5ejd) | The crystal structure of holo T3CT | Descriptor: | 4'-PHOSPHOPANTETHEINE, GLYCEROL, TqaA | Authors: | Zhang, J.R, Tang, Y, Zhou, J.H. | Deposit date: | 2015-11-01 | Release date: | 2016-10-19 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi Nat.Chem.Biol., 12, 2016
|
|
5ISX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5isx by Molmil](/molmil-images/mine/5isx) | |