2QKQ
 
 | | Structure of the SAM Domain of Human Ephrin Type-B Receptor 4 | | Descriptor: | CHLORIDE ION, Ephrin type-B receptor 4 | | Authors: | Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-07-11 | | Release date: | 2007-07-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | SAM Domain of Human Ephrin Type-B Receptor 4 (EPHB4)
TO BE PUBLISHED
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5L1M
 | | CASKIN2 SAM domain tandem | | Descriptor: | Caskin-2 | | Authors: | Donaldson, L.W, Kwan, J.J, Saridakis, V. | | Deposit date: | 2016-07-29 | | Release date: | 2016-08-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.751 Å) | | Cite: | A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.
Cell Commun. Signal, 14, 2016
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1X40
 | | Solution structure of the SAM domain of human ARAP2 | | Descriptor: | ARAP2 | | Authors: | Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-12 | | Release date: | 2005-11-12 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SAM domain of human ARAP2
To be Published
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5J8Y
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1B4F
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4IS7
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1F0M
 | | MONOMERIC STRUCTURE OF THE HUMAN EPHB2 SAM (STERILE ALPHA MOTIF) DOMAIN | | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | | Authors: | Thanos, C.D, Faham, S, Goodwill, K.E, Cascio, D, Phillips, M, Bowie, J.U. | | Deposit date: | 2000-05-16 | | Release date: | 2000-07-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Monomeric structure of the human EphB2 sterile alpha motif domain.
J.Biol.Chem., 274, 1999
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5NZ9
 | | NMR structure of an EphA2-Sam fragment | | Descriptor: | Ephrin type-A receptor 2 | | Authors: | Mercurio, F.A, Leone, M. | | Deposit date: | 2017-05-12 | | Release date: | 2017-12-20 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors.
Sci Rep, 7, 2017
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2LMR
 | | Solution structure of the first sam domain of odin | | Descriptor: | Ankyrin repeat and SAM domain-containing protein 1A | | Authors: | Leone, M, Mercurio, F. | | Deposit date: | 2011-12-12 | | Release date: | 2012-03-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor.
Biochemistry, 51, 2012
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6LUK
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6LUJ
 | | Crystal structure of the SAMD1 SAM domain | | Descriptor: | Atherin, SULFATE ION | | Authors: | Cao, Y, Zhou, Y, Wang, Z. | | Deposit date: | 2020-01-29 | | Release date: | 2021-02-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
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8J1I
 | | Crystal Structure of EphA8/SASH1 Complex | | Descriptor: | Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 | | Authors: | Liu, W, Li, J, Ding, Y. | | Deposit date: | 2023-04-12 | | Release date: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of EphA8 and SASH1 complex at 1.60 Angstroms resolution
To Be Published
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8B10
 | | Crystal Structure of Shank2-SAM mutant domain - L1800W | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | | Deposit date: | 2022-09-08 | | Release date: | 2022-11-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry, 2022
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8ATJ
 | | Crystal Structure of Shank2-SAM domain | | Descriptor: | CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... | | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | | Deposit date: | 2022-08-23 | | Release date: | 2022-11-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.117 Å) | | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry, 2022
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4NL9
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5ZRX
 | | Crystal Structure of EphA2/SHIP2 Complex | | Descriptor: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 | | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | Deposit date: | 2018-04-25 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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5ZRY
 | | Crystal Structure of EphA6/Odin Complex | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... | | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | Deposit date: | 2018-04-25 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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4NJ8
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2MYQ
 | | NMR structure of an Odin-Sam1 fragment | | Descriptor: | Ankyrin repeat and SAM domain-containing protein 1A | | Authors: | Mercurio, F.A, Leone, M. | | Deposit date: | 2015-01-30 | | Release date: | 2015-07-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.
Chembiochem, 16, 2015
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1SGG
 | | THE SOLUTION STRUCTURE OF SAM DOMAIN FROM THE RECEPTOR TYROSINE KINASE EPHB2, NMR, 10 STRUCTURES | | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | | Authors: | Smalla, M, Schmieder, P, Kelly, M, Ter Laak, A, Krause, G, Ball, L, Wahl, M, Bork, P, Oschkinat, H. | | Deposit date: | 1999-01-08 | | Release date: | 1999-10-06 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites.
Protein Sci., 8, 1999
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3HIL
 | | SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) | | Descriptor: | CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION | | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-05-20 | | Release date: | 2009-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1).
To be Published
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1PK3
 | | Scm SAM domain | | Descriptor: | BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA | | Authors: | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | | Deposit date: | 2003-06-04 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
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8UD0
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8UCZ
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6F7M
 | | NMR structure of EphA2-Sam stapled peptides (S13ST) | | Descriptor: | Ephrin type-A receptor 2 | | Authors: | Mercurio, F.A, Leone, M. | | Deposit date: | 2017-12-11 | | Release date: | 2018-08-01 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
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