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PDB: 77 results

8RX9
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BU of 8rx9 by Molmil
LTA4 hydrolase in complex with compound3
Descriptor: 1-[[5-[5-(1~{H}-pyrazol-5-yl)pyridin-2-yl]oxypyridin-2-yl]methyl]piperidin-4-ol, ACETATE ION, IMIDAZOLE, ...
Authors:Srinivas, H.
Deposit date:2024-02-06
Release date:2024-03-20
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.
J.Med.Chem., 67, 2024
7KZE
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BU of 7kze by Molmil
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity
Descriptor: 1-benzyl-4-methoxybenzene, Leukotriene A-4 hydrolase, TRIETHYLENE GLYCOL, ...
Authors:Lee, K.H, Shim, Y, Paige, M, Noble, S.M.
Deposit date:2020-12-10
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.
Sci Rep, 12, 2022
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224931

数据于2024-09-11公开中

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