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PDB: 313 results
3D6C
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BU of 3d6c by Molmil
Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Harms, M.J, Schlessman, J.L, Sue, G.R, Garcia-Moreno, E.B.
Deposit date:2008-05-19
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors.
J.Mol.Biol., 389, 2009
1KDC
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BU of 1kdc by Molmil
STABILIZATION OF A STRAINED PROTEIN LOOP CONFORMATION THROUGH PROTEIN ENGINEERING
Descriptor: STAPHYLOCOCCAL NUCLEASE
Authors:Hodel, A, Fox, R.O.
Deposit date:1994-08-25
Release date:1995-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Stabilization of a strained protein loop conformation through protein engineering.
Protein Sci., 4, 1995
4E6I
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BU of 4e6i by Molmil
Crystal structure of Staphylococcal nuclease variant NVIAGA V99G at cryogenic temperature
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease
Authors:Doctrow, B.M, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2012-03-15
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Local flexibility as a determinant of pKa values of surface ionizable groups in proteins
To be Published
3NHH
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BU of 3nhh by Molmil
Crystal structure of Staphylococcal nuclease variant V23E-L36K at cryogenic temperature
Descriptor: CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Robinson, A.C, Schlessman, J.L, Garcia-Moreno, E.B.
Deposit date:2010-06-14
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
2OEO
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BU of 2oeo by Molmil
Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D
Descriptor: CALCIUM ION, Staphylococcal thermonuclease, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Reynald, R.L, Lattman, E.E, Gittis, A.G.
Deposit date:2006-12-30
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Buried Charges and Water in the Protein Interior: Reality or Fiction?
To be Published
1A2U
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BU of 1a2u by Molmil
STAPHYLOCOCCAL NUCLEASE, V23C VARIANT, COMPLEX WITH 1-N-BUTANE THIOL AND 3',5'-THYMIDINE DIPHOSPHATE
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Wynn, R, Harkins, P.C, Richards, F.M, Fox, R.O.
Deposit date:1998-01-11
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mobile unnatural amino acid side chains in the core of staphylococcal nuclease.
Protein Sci., 5, 1996
2NUC
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BU of 2nuc by Molmil
STAPHLOCOCCAL NUCLEASE, ETHANE THIOL DISULFIDE TO V23C VARIANT
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Wynn, R, Harkins, P.C, Richards, F.M, Fox, R.O.
Deposit date:1997-12-06
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mobile unnatural amino acid side chains in the core of staphylococcal nuclease.
Protein Sci., 5, 1996
3C1F
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BU of 3c1f by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V104K at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B.
Deposit date:2008-01-23
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS V104K at cryogenic temperature
To be Published
2OXP
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BU of 2oxp by Molmil
Crystal Structure of Staphylococcal Nuclease mutant V66D/P117G/H124L/S128A
Descriptor: THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Garcia-Moreno, E.B, Gittis, A.G, Karp, D.A.
Deposit date:2007-02-20
Release date:2007-03-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:High apparent dielectric constant inside a protein reflects structural reorganization coupled to the ionization of an internal asp
Biophys.J., 92, 2007
2EY5
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BU of 2ey5 by Molmil
Crystal structure of Staphylococcal nuclease mutant T41S
Descriptor: Staphylococcal nuclease
Authors:Lu, J.Z, Sakon, J, Stites, W.E.
Deposit date:2005-11-09
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Threonine mutants of Staphylococcal nuclease
To be Published
3E5S
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BU of 3e5s by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS L103K at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B.
Deposit date:2008-08-14
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS L103K at cryogenic temperature
To be Published
3EVQ
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BU of 3evq by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS L25E at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Robinson, A.C, Schlessman, J.L, Garcia-Moreno, E.B.
Deposit date:2008-10-13
Release date:2008-11-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of D+PHS L25E at cryogenic temperature
To be Published
2F0M
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BU of 2f0m by Molmil
Crystal structure of Staphylococcal nuclease mutant V23L/I72V
Descriptor: Staphylococcal nuclease
Authors:Lu, J.Z, Sakon, J, Stites, W.E.
Deposit date:2005-11-13
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophobic core mutants of Staphylococcal nuclease
To be Published
2F0V
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BU of 2f0v by Molmil
Crystal structure of Staphylococcal nuclease mutant V23L/V66L/I72L
Descriptor: Staphylococcal nuclease
Authors:Lu, J.Z, Sakon, J, Stites, W.E.
Deposit date:2005-11-13
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophobic core mutants of Staphylococcal nuclease
To be Published
2RDF
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BU of 2rdf by Molmil
Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature
Descriptor: PHOSPHATE ION, Thermonuclease
Authors:Baran, K, Schlessman, J.L, Garcia-Moreno, B.E.
Deposit date:2007-09-22
Release date:2008-06-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Electrostatic effects in a network of polar and ionizable groups in staphylococcal nuclease.
J.Mol.Biol., 379, 2008
2RKS
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BU of 2rks by Molmil
Crystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperature
Descriptor: PHOSPHATE ION, Thermonuclease
Authors:Schlessman, J.L, Harms, M.J, Garcia-Moreno, E.B.
Deposit date:2007-10-17
Release date:2008-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:A buried lysine that titrates with a normal pKa: role of conformational flexibility at the protein-water interface as a determinant of pKa values.
Protein Sci., 17, 2008
1A3U
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BU of 1a3u by Molmil
STAPHYLOCOCCAL NUCLEASE, CYCLOHEXANE THIOL DISULFIDE TO V23C VARIANT
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Wynn, R, Harkins, P.C, Richards, F.M, Fox, R.O.
Deposit date:1998-01-24
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Comparison of straight chain and cyclic unnatural amino acids embedded in the core of staphylococcal nuclease.
Protein Sci., 6, 1997
2ENB
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BU of 2enb by Molmil
CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
Descriptor: STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Libson, A, Gittis, A, Lattman, E.E.
Deposit date:1994-03-23
Release date:1994-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
Biochemistry, 33, 1994
2F0P
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BU of 2f0p by Molmil
Crystal structure of Staphylococcal nuclease mutant V66I/V99I
Descriptor: Staphylococcal nuclease
Authors:Lu, J.Z, Sakon, J, Stites, W.E.
Deposit date:2005-11-13
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Hydrophobic core mutants of Staphylococcal nuclease
To be Published
4K8I
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BU of 4k8i by Molmil
Crystal Structure of Staphylococcal Nuclease mutant I92V/V99L
Descriptor: Thermonuclease
Authors:Sanders, J.M, Latimer, E.C, Roeser, J.R, Janowska, K, Sakon, J, Stites, W.E.
Deposit date:2013-04-18
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrophobic core mutants of Staphylococcal nuclease
To be Published
1AEX
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BU of 1aex by Molmil
STAPHYLOCOCCAL NUCLEASE, METHANE THIOL DISULFIDE TO V23C VARIANT
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Wynn, R, Harkins, P.C, Richards, F.M, Fox, R.O.
Deposit date:1997-03-01
Release date:1997-06-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mobile unnatural amino acid side chains in the core of staphylococcal nuclease.
Protein Sci., 5, 1996
5EKK
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BU of 5ekk by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V39D/L125E at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Skerritt, L.A, Bell-Upp, P.C, Siegler, M.A, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2015-11-03
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS V39D/L125E at cryogenic temperature
To be Published
6XSE
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BU of 6xse by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS F34Y at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2020-07-15
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS F34Y at cryogenic temperature
To be Published
3D4D
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BU of 3d4d by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS Y91E at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B.
Deposit date:2008-05-14
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS Y91E at cryogenic temperature.
To be Published
1U9R
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BU of 1u9r by Molmil
Crystal Structure of Staphylococcal Nuclease mutant V66E/P117G/H124L/S128A at Room Temperature
Descriptor: Thermonuclease
Authors:Denisov, V.P, Schlessman, J.L, Garcia-Moreno, B.E, Halle, B.
Deposit date:2004-08-10
Release date:2004-12-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stabilization of internal charges in a protein: water penetration or conformational change?
Biophys.J., 87, 2004

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数据于2024-07-10公开中

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