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PDB: 1 results
5V6Y
Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
Descriptor:
ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:
Pioszak, A
,
Booe, J.
Deposit date:
2017-03-17
Release date:
2018-01-31
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.8 Å)
Cite:
Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
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数据于2024-09-11公开中