8EY2
| Cryo-EM structure of SARS-CoV-2 Main protease C145S in complex with N-terminal peptide | Descriptor: | 3C-like proteinase | Authors: | Noske, G.D, Song, Y, Fernandes, R.S, Oliva, G, Godoy, A.S. | Deposit date: | 2022-10-26 | Release date: | 2022-12-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition. Nat Commun, 14, 2023
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8EYJ
| Crystal Structure of uncleaved SARS-CoV-2 Main Protease C145S mutant in complex with Nirmatrelvir | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Noske, G.D, Godoy, A.S, Oliva, G. | Deposit date: | 2022-10-27 | Release date: | 2022-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.738 Å) | Cite: | An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition. Nat Commun, 14, 2023
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