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PDB: 3 results

Crystal structure of PPARgamma ligand binding domain in complex with SMRT peptide and inverse agonist T0070907
Descriptor:	2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Nuclear receptor corepressor 2, Peroxisome proliferator-activated receptor gamma
Authors:	Shang, J, Kojetin, D.J.
Deposit date:	2019-06-19
Release date:	2020-03-04
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	A molecular switch regulating transcriptional repression and activation of PPAR gamma. Nat Commun, 11, 2020

Crystal structure of PPARgamma ligand binding domain in complex with N-CoR peptide and inverse agonist T0070907
Descriptor:	2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, NCOR isoform c, Peroxisome proliferator-activated receptor gamma
Authors:	Shang, J, Kojetin, D.J.
Deposit date:	2019-04-22
Release date:	2020-03-04
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	A molecular switch regulating transcriptional repression and activation of PPAR gamma. Nat Commun, 11, 2020

Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone
Descriptor:	2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Mediator of RNA polymerase II transcription subunit 1, ...
Authors:	Shang, J, Kojetin, D.J.
Deposit date:	2019-04-22
Release date:	2020-03-04
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	A molecular switch regulating transcriptional repression and activation of PPAR gamma. Nat Commun, 11, 2020