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A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders
Descriptor:	(2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E
Authors:	Papadopoulos, E.
Deposit date:	2021-04-07
Release date:	2021-04-28
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.91 Å)
Cite:	A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur.J.Med.Chem., 219, 2021