PDB: 224004 resultsInfo pagesStatus searchChemie searchBIRD

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8OZZ	PH domain of AKT-like kinase in Trypanosoma cruzi Descriptor: PH domain of Akt-like kinase in Trypanosoma cruzi Authors: Stadler, K.A, Ortiz-Joya, L.J, Zangger, K, Gubensaek, N. Deposit date: 2023-05-09 Release date: 2024-05-08 Method: SOLUTION NMR Cite: Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease. Sci Rep, 14, 2024
8OVG	Human Mitochondrial Lon Y186E Mutant ADP Bound Descriptor: Lon protease homolog, mitochondrial Authors: Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. Deposit date: 2023-04-26 Release date: 2024-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (8.47 Å) Cite: Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
8P8E	Crystal structure of endolysin gp46 from Pseudomonas aeruginosa bacteriophage vB_PaeM_KTN6 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Glycoside hydrolase family protein Authors: van Raaij, M.J, Sanz-Gaitero, M. Deposit date: 2023-06-01 Release date: 2024-05-08 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (1.391 Å) Cite: Structural and Biochemical Characterization of a New Phage-Encoded Muramidase, KTN6 Gp46. Phage (New Rochelle), 5, 2024
7PYN	Structure of an LPMO (expressed in E.coli) at 2.31x10^5 Gy Descriptor: Auxiliary activity 9, COPPER (II) ION, SULFATE ION Authors: Tandrup, T, Muderspach, S.J, Banerjee, S, Ipsen, J.O, Rollan, C.H, Norholm, M.H.H, Johansen, K.S, Lo Leggio, L. Deposit date: 2021-10-10 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
8P22	X-ray structure of acetylcholine-binding protein (AChBP) in complex with IOTA376. Descriptor: 2-[(2~{R})-1-ethylimidazolidin-2-yl]-6-pyridin-2-yl-pyridine, Acetylcholine-binding protein, GLYCEROL, ... Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2023-05-14 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
8OV9	Crystal structure of Ene-reductase 1 from black poplar mushroom Descriptor: Ene-reductase 1, GLYCEROL Authors: Korf, L, Essen, L.-O, Karrer, D, Ruehl, M. Deposit date: 2023-04-25 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Shifting the substrate scope of an ene/yne-reductase by loop engineering To Be Published
8P14	USP28 USP domain in complex with Vismodegib Descriptor: 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 28 Authors: Sauer, F, Karal Nair, R, Kisker, C. Deposit date: 2023-05-11 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.57 Å) Cite: USP28 USP domain in complex with Vismodegib To Be Published
8P1P	USP28 in complex with AZ1 Descriptor: 2-[[5-bromanyl-2-[[4-fluoranyl-3-(trifluoromethyl)phenyl]methoxy]phenyl]methylamino]ethanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Sauer, F, Karal-Nair, R, Kisker, C. Deposit date: 2023-05-12 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.76 Å) Cite: USP28 in complex with AZ1 To Be Published
5L0Q	Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ... Authors: Xu, K, Saha, N, Nikolov, D.B. Deposit date: 2016-07-28 Release date: 2016-11-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.759 Å) Cite: An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. J.Exp.Med., 213, 2016
8P1K	Structure of hantaan orthohantavirus (HTNV) polymerase - Apo core endonuclease Descriptor: RNA-directed RNA polymerase L Authors: Keown, J.R, Carrique, L, Grimes, J.M. Deposit date: 2023-05-12 Release date: 2024-05-22 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structure of hantaan orthohantavirus (HTNV) polymerase - Apo core endonuclease To Be Published
8P2O	Dimeric mutant S103R of the BTB domain of ZBTB8A from Xenopus laevis Descriptor: 1,2-ETHANEDIOL, Zinc finger and BTB domain-containing protein 8A.1-A Authors: Coste, F, Mance, L, Pukalo, Z, Suskiewicz, M.J. Deposit date: 2023-05-16 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Dimeric mutant S103R of the BTB domain of ZBTB8A from Xenopus laevis To Be Published
8P2P	Polymeric form of the BTB domain of human ZBTB18 Descriptor: Zinc finger and BTB domain-containing protein 18 Authors: Coste, F, Mance, L, Pukalo, Z, Suskiewicz, M.J. Deposit date: 2023-05-16 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (4.15 Å) Cite: Polymeric form of the BTB domain of human ZBTB18 To Be Published
8P11	X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL003044. Descriptor: 4-(4-chlorophenyl)piperidin-4-ol, Acetylcholine-binding protein, CHLORIDE ION, ... Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2023-05-11 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
8OV5	PERIDININ-CHLOROPHYLL-PROTEIN OF AMPHIDINIUM CARTERAE, 100K Descriptor: CHLOROPHYLL A, PERIDININ, Peridinin-chlorophyll a-binding protein 1, ... Authors: Hofmann, E, Johanning, S. Deposit date: 2023-04-25 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Structural and Spectroscopic Characterization of the Peridinin-Chlorophyll a-Protein (PCP) Complex from Heterocapsa pygmaea (HPPCP) To Be Published
7PYL	Structure of an LPMO (expressed in E.coli) at 1.49x10^4 Gy Descriptor: ACETATE ION, Auxiliary activity 9, COPPER (II) ION, ... Authors: Tandrup, T, Muderspach, S.J, Banerjee, S, Ipsen, J.O, Rollan, C.H, Norholm, M.H.H, Johansen, K.S, Lo Leggio, L. Deposit date: 2021-10-10 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
8OXR	Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A Descriptor: Thrombospondin type-1 domain-containing protein 7A Authors: Bochel, A, Mortensen, S.A, Chojnowski, G, Wilmanns, M. Deposit date: 2023-05-02 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A To Be Published
8OYQ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 Descriptor: Chemotaxis protein CheA, quinazolin-2-amine Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 To Be Published
7PYM	Structure of an LPMO (expressed in E.coli) at 5.61x10^4 Gy Descriptor: Auxiliary activity 9, COPPER (II) ION, SULFATE ION Authors: Tandrup, T, Muderspach, S.J, Banerjee, S, Ipsen, J.O, Rollan, C.H, Norholm, M.H.H, Johansen, K.S, Lo Leggio, L. Deposit date: 2021-10-10 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
8P7G	Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS Descriptor: Paired mesoderm homeobox protein 2B Authors: Russo, L, Diana, D, Fattorusso, R. Deposit date: 2023-05-30 Release date: 2024-05-15 Last modified: 2024-06-26 Method: SOLUTION NMR Cite: Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS. Chem Sci, 15, 2024
8OV8	Crystal structure of Ene-reductase 1 from black poplar mushroom in complex to NADP Descriptor: Ene-reductase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... Authors: Korf, L, Essen, L.-O, Karrer, D, Ruehl, M. Deposit date: 2023-04-25 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Shifting the substrate scope of an ene/yne-reductase by loop engineering To Be Published
8OYD	TrkB transmembrane domain NMR structure in DMPC/DHPC bicelles Descriptor: BDNF/NT-3 growth factors receptor Authors: Kot, E.F, Mineev, K.S, Goncharuk, S.A. Deposit date: 2023-05-04 Release date: 2024-05-15 Method: SOLUTION NMR Cite: Structural Basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB To Be Published
1ASJ	P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE Authors: Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. Deposit date: 1997-08-11 Release date: 1997-12-03 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
8P9M	Hexameric Hfq from Chromobacterium haemolyticum Descriptor: GLYCEROL, RNA-binding protein Hfq Authors: Nikulin, A.D, Lekontseva, N.V. Deposit date: 2023-06-06 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2 Å) Cite: The Structure of the Hfq Protein from Chromobacterium haemolyticum Revealed a New Variant of Regulation of RNA Binding with the Protein Crystallography Reports, 68, 2023
8OYZ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 Descriptor: 2-azanyl-7,8-dihydro-6~{H}-quinazolin-5-one, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 To Be Published
8OZ9	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 Descriptor: 7-(1~{H}-1,2,3-triazol-5-yl)quinazolin-2-amine, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-08 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 To Be Published

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