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1B6Q
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BU of 1b6q by Molmil
ALANINE 31 PROLINE MUTANT OF ROP PROTEIN
Descriptor: ROP
Authors:Glykos, N, Cesareni, G, Kokkinidis, M.
Deposit date:1999-01-16
Release date:1999-07-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protein plasticity to the extreme: changing the topology of a 4-alpha-helical bundle with a single amino acid substitution.
Structure Fold.Des., 7, 1999
1BDA
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BU of 1bda by Molmil
CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE)
Descriptor: N-{[5-(dimethylamino)naphthalen-2-yl]sulfonyl}-L-alpha-glutamyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl) butyl]glycinamide, SINGLE CHAIN TISSUE TYPE PLASMINOGEN ACTIVATOR
Authors:Bode, W, Renatus, M, Engh, R.A.
Deposit date:1998-05-07
Release date:1999-05-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.
EMBO J., 16, 1997
2CM0
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BU of 2cm0 by Molmil
The PUB domain functions as a p97 binding module in human peptide N-glycanase.
Descriptor: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, PEPTIDE N-GLYCANASE HOMOLOG
Authors:Allen, M.D, Buchberger, A, Bycroft, M.
Deposit date:2006-05-03
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Pub Domain Functions as a P97 Binding Module in Human Peptide N-Glycanase.
J.Biol.Chem., 281, 2006
1B6V
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BU of 1b6v by Molmil
CRYSTAL STRUCTURE OF A HYBRID BETWEEN RIBONUCLEASE A AND BOVINE SEMINAL RIBONUCLEASE
Descriptor: RIBONUCLEASE
Authors:Vatzaki, E.H, Allen, S.C, Leonidas, D.D, Acharya, K.R.
Deposit date:1999-01-18
Release date:1999-06-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution.
Eur.J.Biochem., 260, 1999
1B76
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BU of 1b76 by Molmil
GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glycine--tRNA ligase
Authors:Arnez, J.G, Moras, D.
Deposit date:1999-01-27
Release date:1999-01-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine.
J.Mol.Biol., 286, 1999
2C9M
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BU of 2c9m by Molmil
Structure of (SR) Calcium-ATPase in the Ca2E1 state solved in a P1 crystal form.
Descriptor: CALCIUM ION, CHLORIDE ION, POTASSIUM ION, ...
Authors:Lund Jensen, A.-M, Sorensen, T.L.-M, Olesen, C, Moller, J.V, Nissen, P.
Deposit date:2005-12-13
Release date:2006-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump
Embo J., 25, 2006
1BDT
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BU of 1bdt by Molmil
WILD TYPE GENE-REGULATING PROTEIN ARC/DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*TP*GP*AP*TP*AP*GP*AP*AP*GP*CP*AP*CP*TP*CP*TP*AP*CP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*GP*TP*AP*GP*AP*GP*TP*GP*CP*TP*TP*CP*TP*AP*TP*CP*AP*T)-3'), PROTEIN (GENE-REGULATING PROTEIN ARC)
Authors:Schilbach, J.F, Karzai, A.W, Raumann, B.E, Sauer, R.T.
Deposit date:1998-05-11
Release date:1999-02-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Origins of DNA-binding specificity: role of protein contacts with the DNA backbone.
Proc.Natl.Acad.Sci.USA, 96, 1999
1B87
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BU of 1b87 by Molmil
CRYSTAL STRUCTURE OF AN AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE
Descriptor: ACETYL COENZYME *A, PROTEIN (AMINOGLYCOSIDE N6'-ACETYLTRANSFERASE TYPE 1)
Authors:Wybenga-Groot, L.E, Berghuis, A.M.
Deposit date:1999-02-09
Release date:1999-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold.
Structure Fold.Des., 7, 1999
2C6X
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BU of 2c6x by Molmil
Structure of Bacillus subtilis citrate synthase
Descriptor: CITRATE SYNTHASE 1, CITRIC ACID, COENZYME A
Authors:Vogl, C, Hough, D.W, Danson, M.J, Crennell, S.J.
Deposit date:2005-11-14
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Domain Closure in Citrate Synthases Adapted to the Range of Biological Temperatures
To be Published
1B8S
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BU of 1b8s by Molmil
CHOLESTEROL OXIDASE FROM STREPTOMYCES GLU361GLN MUTANT
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE)
Authors:Vrielink, A, Yue, Q.K.
Deposit date:1999-02-02
Release date:1999-02-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
1B9B
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BU of 1b9b by Molmil
TRIOSEPHOSPHATE ISOMERASE OF THERMOTOGA MARITIMA
Descriptor: PROTEIN (TRIOSEPHOSPHATE ISOMERASE), SULFATE ION
Authors:Maes, D, Wierenga, R.K.
Deposit date:1999-02-09
Release date:2000-01-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The crystal structure of triosephosphate isomerase (TIM) from Thermotoga maritima: a comparative thermostability structural analysis of ten different TIM structures.
Proteins, 37, 1999
1BI9
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BU of 1bi9 by Molmil
RETINAL DEHYDROGENASE TYPE TWO WITH NAD BOUND
Descriptor: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, RETINAL DEHYDROGENASE TYPE II
Authors:Newcomer, M.E, Lamb, A.L.
Deposit date:1998-06-23
Release date:1999-07-22
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity.
Biochemistry, 38, 1999
1AZ5
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BU of 1az5 by Molmil
UNLIGANDED SIV PROTEASE STRUCTURE IN AN "OPEN" CONFORMATION
Descriptor: SIV PROTEASE
Authors:Rose, R.B, Craik, C.S, Stroud, R.M.
Deposit date:1997-11-25
Release date:1998-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain flexibility in retroviral proteases: structural implications for drug resistant mutations.
Biochemistry, 37, 1998
1BAM
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BU of 1bam by Molmil
STRUCTURE OF RESTRICTION ENDONUCLEASE BAMHI PHASED AT 1.95 ANGSTROMS RESOLUTION BY MAD ANALYSIS
Descriptor: ENDONUCLEASE BamH I
Authors:Aggarwal, A.K, Newman, M.
Deposit date:1994-12-28
Release date:1995-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of restriction endonuclease bamhi phased at 1.95 A resolution by MAD analysis.
Structure, 2, 1994
2C6W
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BU of 2c6w by Molmil
PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1A, ZINC ION
Authors:Contreras-Martel, C, Job, V, Di Guilmi, A.-M, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2005-11-14
Release date:2005-12-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
2CEJ
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BU of 2cej by Molmil
P1' Extended HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold
Descriptor: 3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE, POL PROTEIN
Authors:Ginman, N, Ekegren, J.K, Johansson, A, Wallberg, H, Larhed, M, Samuelsson, B, Hallberg, A, Unge, T.
Deposit date:2006-02-07
Release date:2007-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Microwave-Accelerated Synthesis of P1'-Extended HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold
J.Med.Chem., 49, 2006
1AQC
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BU of 1aqc by Molmil
X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
Descriptor: PEPTIDE, X11
Authors:Lee, C.-H, Zhang, Z, Kuriyan, J.
Deposit date:1997-07-28
Release date:1997-12-24
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
1AXW
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BU of 1axw by Molmil
E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, THYMIDYLATE SYNTHASE
Authors:Stout, T.J, Sage, C.R, Stroud, R.M.
Deposit date:1997-10-23
Release date:1998-10-28
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Thymidylate Synthase Inhibitors Using Flexible Docking and an Empirically Tuned Scoring Function
To be Published
1APY
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BU of 1apy by Molmil
HUMAN ASPARTYLGLUCOSAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTYLGLUCOSAMINIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Rouvinen, J, Oinonen, C.
Deposit date:1995-06-14
Release date:1996-12-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of human lysosomal aspartylglucosaminidase.
Nat.Struct.Biol., 2, 1995
1ART
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BU of 1art by Molmil
X-RAY CRYSTALLOGRAPHIC STUDY OF PYRIDOXAL 5'-PHOSPHATE-TYPE ASPARTATE AMINOTRANSFERASES FROM ESCHERICHIA COLI IN OPEN AND CLOSED FORM
Descriptor: 2-methyl-L-aspartic acid, ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okamoto, A, Higuchi, T, Hirotsu, K.
Deposit date:1993-08-02
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from Escherichia coli in open and closed form.
J.Biochem.(Tokyo), 116, 1994
1ARW
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BU of 1arw by Molmil
CRYSTAL STRUCTURES OF CYANIDE-AND TRIIODIDE-BOUND FORMS OF ARTHROMYCES RAMOSUS PEROXIDASE AT DIFFERENT PH VALUES. PERTURBATIONS OF ACTIVE SITE RESIDUES AND THEIR IMPLICATION IN ENZYME CATALYSIS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ...
Authors:Fukuyama, K, Kunishima, N, Amada, F.
Deposit date:1995-04-25
Release date:1996-01-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis.
J.Biol.Chem., 270, 1995
2CI5
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BU of 2ci5 by Molmil
Crystal structure of Dimethylarginine Dimethylaminohydrolase I in complex with L-homocysteine
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, CITRIC ACID, NG, ...
Authors:Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G.
Deposit date:2006-03-17
Release date:2006-05-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors
Structure, 14, 2006
1ASX
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BU of 1asx by Molmil
APICAL DOMAIN OF THE CHAPERONIN FROM THERMOPLASMA ACIDOPHILUM
Descriptor: PHOSPHATE ION, THERMOSOME
Authors:Klumpp, M, Baumeister, W, Essen, L.-O.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the substrate binding domain of the thermosome, an archaeal group II chaperonin.
Cell(Cambridge,Mass.), 91, 1997
2C9E
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BU of 2c9e by Molmil
Peridinin-chlorophyll a protein, high-salt form
Descriptor: CHLOROPHYLL A, DIGALACTOSYL DIACYL GLYCEROL (DGDG), MAGNESIUM ION, ...
Authors:Schulte, T, Sharples, F.P, Hiller, R.G, Hofmann, E.
Deposit date:2005-12-09
Release date:2007-02-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-Ray Structure of the High-Salt Form of the Peridinin-Chlorophyll A-Protein from the Dinoflagellate Amphidinium Carterae: Modulation of the Spectral Properties of Pigments by the Protein Environment.
Biochemistry, 48, 2009
1BCP
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BU of 1bcp by Molmil
BINARY COMPLEX OF PERTUSSIS TOXIN AND ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PERTUSSIS TOXIN
Authors:Hazes, B, Read, R.J.
Deposit date:1995-11-21
Release date:1997-06-05
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the pertussis toxin-ATP complex: a molecular sensor.
J.Mol.Biol., 258, 1996

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