PDB: 52677 resultsInfo pagesStatus searchChemie searchBIRD

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6PGC	WDR5delta32 bound to methyl benzyl(4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate Descriptor: SULFATE ION, WD repeat-containing protein 5, methyl benzyl{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
5XF0	Solution structure of the IgI domain of CD147 Descriptor: Basigin Authors: Jin, S.J, Xia, B. Deposit date: 2017-04-06 Release date: 2018-04-11 Method: SOLUTION NMR Cite: Zn(II) can mediate self-association of the extracellular C-terminal domain of CD147 Protein Cell, 9, 2018
6PG7	WDR5delta32 bound to (2-(3-methoxy-3-phenylpropyl)-1H-imidazol-4-yl)methanol Descriptor: DI(HYDROXYETHYL)ETHER, WD repeat-containing protein 5, {2-[(3S)-3-methoxy-3-phenylpropyl]-1H-imidazol-4-yl}methanol Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
6PGD	WDR5delta32 bound to peptidomimetic Descriptor: N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide, SULFATE ION, WD repeat-containing protein 5 Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
6PGQ	Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Calcitonin, ... Authors: Lee, S, Pioszak, A.A. Deposit date: 2019-06-24 Release date: 2020-02-12 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics. J.Mol.Biol., 432, 2020
6P05	Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27 Descriptor: Bromodomain-containing protein 4, GLYCEROL, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide Authors: Ratia, K.M, Xiong, R, Li, Y, Zhao, J, Gutgesell, L.M, Shen, Z, Dye, K, Dubrovyskyii, O, Zhao, H, Huang, F, Tonetti, D.A, Thatcher, G.R. Deposit date: 2019-05-16 Release date: 2020-05-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
8SHE	CCT-G beta 5 complex closed state 8 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-13 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHD	CCT G beta 5 complex closed state 10 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-13 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHP	CCT G beta 5 complex closed state 13 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
6PPT	Structural Basis for Client Recognition and Activity of Hsp40 Chaperones Descriptor: Alkaline phosphatase,Chaperone protein DnaJ 2 fusion Authors: Jiang, Y, Rossi, P, Kalodimos, C.G. Deposit date: 2019-07-08 Release date: 2019-09-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis for client recognition and activity of Hsp40 chaperones. Science, 365, 2019
8SGL	CCT G beta 5 complex closed state 15 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-12 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
6P5V	Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide Authors: Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. Deposit date: 2019-05-31 Release date: 2019-09-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.398 Å) Cite: Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
8SHA	CCT-G beta 5 complex closed state 4 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-13 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHO	CCT G beta 5 complex close state 11 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SFE	Open state CCT-G beta 5 complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-10 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHT	CCT G beta 5 complex closed state 14 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHL	CCT G beta 5 complex closed state 5 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SH9	CCT G beta 5 complex best PhLP1 class Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-13 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SFF	CCT G beta 5 complex closed state 0 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-11 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SG9	CCT G beta 5 complex closed state 3 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-12 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SGQ	CCT G beta 5 complex intermediate state Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-12 Release date: 2023-11-01 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SGC	CCT G beta 5 complex closed state 2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-12 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHN	CCT-G beta 5 complex closed state 6 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SG8	CCT G beta 5 complex closed state 1 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-11 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
8SHG	CCT G beta 5 complex closed state 9 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... Authors: Wang, S, Sass, M, Willardson, B.M, Shen, P.S. Deposit date: 2023-04-14 Release date: 2023-10-25 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023

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