7B62
| Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pye, V.E, Rosa, A, Roustan, C, Cherepanov, P. | Deposit date: | 2020-12-07 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
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5OP8
| Factor Inhibiting HIF (FIH) in complex with zinc and Molidustat | Descriptor: | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)-1~{H}-pyrazol-3-one, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Leissing, T.M, Schofield, C.J, Clifton, I.J, Lu, X. | Deposit date: | 2017-08-09 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chem Sci, 8, 2017
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7AYG
| oxalyl-CoA decarboxylase from Methylorubrum extorquens with bound TPP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative oxalyl-CoA decarboxylase (Oxc, ... | Authors: | Pfister, P, Burgener, S, Nattermann, M, Zarzycki, J, Erb, T.J. | Deposit date: | 2020-11-12 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism. Acs Catalysis, 11, 2021
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7B2E
| quadruple mutant of oxalyl-CoA decarboxylase from Methylorubrum extorquens with bound TPP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative oxalyl-CoA decarboxylase (Oxc, ... | Authors: | Pfister, P, Burgener, S, Nattermann, M, Zarzycki, J, Erb, T.J. | Deposit date: | 2020-11-26 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism. Acs Catalysis, 11, 2021
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7AUE
| Melanocortin receptor 4 (MC4R) Gs protein complex | Descriptor: | AMINOSERINE, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Degtjarik, O, Israeli, H, Prabahar, V, Shalev-Benami, M. | Deposit date: | 2020-11-02 | Release date: | 2021-04-28 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling. Science, 372, 2021
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7OCF
| Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ... | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | Deposit date: | 2021-04-26 | Release date: | 2021-06-09 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor. Nature, 594, 2021
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7B2L
| Structure of the endocytic adaptor complex AENTH | Descriptor: | ANTH domain of Sla2, ENTH domain of epsin Ent1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Klebl, D.P, Lizarrondo, J, Sobott, F, Garcia-Alai, M, Muench, S.P. | Deposit date: | 2020-11-27 | Release date: | 2021-05-05 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis. Nat Commun, 12, 2021
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7ASW
| Crystal structure of chloroplastic thioredoxin z defines a novel type-specific target recognition | Descriptor: | Thioredoxin-related protein CITRX | Authors: | Le Moigne, T, Gurrieri, L, Crozet, P, Marchand, C.H, Zaffagnini, M, Sparla, F, Lemaire, S.D, Henri, J. | Deposit date: | 2020-10-28 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Crystal structure of chloroplastic thioredoxin z defines a type-specific target recognition. Plant J., 107, 2021
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7O3I
| Cystal structure of Zymogen Granule Protein 16 (ZG16) | Descriptor: | CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16 | Authors: | Javitt, G, Fass, D. | Deposit date: | 2021-04-01 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Conformational switches and redox properties of the colon cancer-associated human lectin ZG16. Febs J., 288, 2021
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7YRG
| histone methyltransferase | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | Authors: | Li, H, Wang, W.Y. | Deposit date: | 2022-08-09 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
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7O4P
| Cystal structure of Zymogen Granule Protein 16 (ZG16) | Descriptor: | CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16 | Authors: | Javitt, G, Fass, D. | Deposit date: | 2021-04-07 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Conformational switches and redox properties of the colon cancer-associated human lectin ZG16. Febs J., 288, 2021
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7O88
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7YP1
| Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 10E4 (localized refinement) | Descriptor: | 10E4 heavy chain, 10E4 light chain, EBV gH, ... | Authors: | Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. | Deposit date: | 2022-08-02 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
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7OBZ
| Structure of RsLOV D109G | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, LOV protein, ... | Authors: | Moeglich, A, Krafft, T.G.A, Weyand, M. | Deposit date: | 2021-04-25 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Light-Oxygen-Voltage Receptor Integrates Light and Temperature. J.Mol.Biol., 433, 2021
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7O3X
| Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Protein sll0617 | Authors: | Gupta, T.K, Klumpe, S, Gries, K, Strauss, M, Rudack, T, Schuller, J.M, Schroda, M, Engel, B.D. | Deposit date: | 2021-04-03 | Release date: | 2021-06-30 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity. Cell, 184, 2021
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7O40
| Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Protein sll0617 | Authors: | Gupta, T.K, Klumpe, S, Gries, K, Strauss, M, Rudack, T, Schuller, J.M, Schroda, M, Engel, B.D. | Deposit date: | 2021-04-03 | Release date: | 2021-06-30 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity. Cell, 184, 2021
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7NPJ
| Crystal structure of Mycobacterium tuberculosis ArgC in complex with 6-phenoxy-3-pyridinamine | Descriptor: | 6-phenoxy-3-pyridinamine, N-acetyl-gamma-glutamyl-phosphate reductase | Authors: | Gupta, P, Mendes, V, Blundell, T.L. | Deposit date: | 2021-02-27 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
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7O4F
| The DYW domain of A. thaliana OTP86 in its active state | Descriptor: | Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION | Authors: | Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S. | Deposit date: | 2021-04-06 | Release date: | 2021-06-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. Nat Catal, 4, 2021
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7O4E
| The DYW domain of A. thaliana OTP86 in its inactive state | Descriptor: | Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION | Authors: | Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S. | Deposit date: | 2021-04-06 | Release date: | 2021-06-30 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. Nat Catal, 4, 2021
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7YO2
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7NYY
| Cryo-EM structure of the MukBEF monomer | Descriptor: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7YO4
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7YO5
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7O2A
| X-RAY STRUCTURE OF SMYD3 IN COMPLEX WITH benzodiazepine-type inhibitor compound 15 | Descriptor: | (2S)-1-(4-azanylpiperidin-1-yl)carbonyl-N-(2-cyclopropylethyl)-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | Authors: | Steuber, H. | Deposit date: | 2021-03-30 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Slas Discov, 26, 2021
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7YNZ
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