8ENU
| Structure of the C3bB proconvertase in complex with lufaxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | Authors: | Andersen, J.F, Lei, H. | Deposit date: | 2022-09-30 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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7WEM
| Solid-state NMR Structure of TFo c-Subunit Ring | Descriptor: | ATP synthase subunit c | Authors: | Akutsu, H, Todokoro, Y, Kang, S.-J, Suzuki, T, Yoshida, M, Ikegami, T, Fujiwara, T. | Deposit date: | 2021-12-23 | Release date: | 2022-08-10 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Chemical Conformation of the Essential Glutamate Site of the c -Ring within Thermophilic Bacillus F o F 1 -ATP Synthase Determined by Solid-State NMR Based on its Isolated c -Ring Structure. J.Am.Chem.Soc., 144, 2022
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7UO6
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8FVG
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7M73
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7M79
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6OKX
| Solution structure of VEK50RH1/AA | Descriptor: | Plasminogen-binding group A streptococcal M-like protein PAM | Authors: | Yuan, Y, Castellino, F.J. | Deposit date: | 2019-04-15 | Release date: | 2020-02-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes. J.Struct.Biol., 208, 2019
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7ULY
| MicroED structure of triclinic lysozyme | Descriptor: | Lysozyme C, NITRATE ION | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Gonen, T. | Deposit date: | 2022-04-05 | Release date: | 2023-03-15 | Last modified: | 2024-10-09 | Method: | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | Cite: | Hydrogens and hydrogen-bond networks in macromolecular MicroED data. J Struct Biol X, 6, 2022
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7KUC
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8FGX
| Cryo-EM structure of the STAR-0215 Fab in complex with active human plasma kallikrein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein light chain, STAR-0215 Heavy chain, ... | Authors: | Fuller, J.R, Biris, N, Bista, P. | Deposit date: | 2022-12-13 | Release date: | 2023-09-06 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | STAR-0215 is a Novel, Long-Acting Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Potential Treatment of Hereditary Angioedema. J.Pharmacol.Exp.Ther., 387, 2023
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6QYW
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - nisin ring A | Descriptor: | ILE-DBU-DAL-ILE-DHA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6GJQ
| human NBD1 of CFTR in complex with nanobody T27 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, Nanobody T27 | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | Deposit date: | 2018-05-16 | Release date: | 2019-06-19 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
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7JOF
| Calcium-bound C2A Domain from Human Dysferlin | Descriptor: | CALCIUM ION, Isoform 6 of Dysferlin | Authors: | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | Deposit date: | 2020-08-06 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem.J., 478, 2021
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6GKD
| human NBD1 of CFTR in complex with nanobodies D12 and G3a | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ... | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | Deposit date: | 2018-05-18 | Release date: | 2019-06-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
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7UBI
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6QYS
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Nisin Ring B | Descriptor: | DBB-PRO-GLY-CYS-LYS | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYV
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A (Ser2, Ala5, Ala8) analogue | Descriptor: | PHE-SER-DAL-LEU-ALA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6R14
| Structure of kiteplatinated dsDNA | Descriptor: | Kiteplatin, Kiteplatinated DNA oligomer, chain A, ... | Authors: | Margiotta, N, Papadia, P, Kubicek, K, Krejcikova, M, Gkionis, K, Sponer, J. | Deposit date: | 2019-03-13 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural characterization of kiteplatinated DNA To Be Published
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7UI5
| Evolution avoids a pathological stabilizing interaction in the immune protein S100A9 | Descriptor: | CALCIUM ION, Protein S100-A9 | Authors: | Reardon, P.N, Harman, J.L, Costello, S.M, Warren, G.D, Phillips, S.R, Connor, P.J, Marqusee, S, Harms, M.J. | Deposit date: | 2022-03-28 | Release date: | 2022-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9. Proc.Natl.Acad.Sci.USA, 119, 2022
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6TPH
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5JOJ
| Calcium-loaded EF-hand domain of L-plastin | Descriptor: | CALCIUM ION, Plastin-2 | Authors: | Ishida, H, Jensen, K.V, Woodman, G.W, Hyndman, M.E, Vogel, H.J. | Deposit date: | 2016-05-02 | Release date: | 2017-04-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling. Sci Rep, 7, 2017
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6R3C
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8GG6
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #12 of 20) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-03-08 | Release date: | 2024-03-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8GGK
| Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #3 of 20) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-03-08 | Release date: | 2024-03-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8GGV
| Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #14 of 20) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-03-08 | Release date: | 2024-03-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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