PDB: 72372 resultsInfo pagesStatus searchChemie searchBIRD

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3WI0	P453H/I471T mutant of PB2 middle domain from influenza virus A/Puerto Rico/8/34(H1N1) Descriptor: Polymerase basic protein 2 Authors: Tsurumura, T, Yoshida, T, Tsuge, H. Deposit date: 2013-09-04 Release date: 2013-12-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Conformational Polymorphism of m7GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus Plos One, 8, 2013
6P1A	Transcription antitermination factor Q21 in complex with Q21-binding-element DNA Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*TP*TP*GP*CP*TP*CP*AP*TP*TP*TP*GP*CP*TP*CP*AP*AP*TP*GP*AP*G)-3'), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2019-05-19 Release date: 2019-06-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.837 Å) Cite: Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
5C2Y	Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription) Descriptor: GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ... Authors: Yogesha, S.D, Irani, S, Zhang, Y.J. Deposit date: 2015-06-16 Release date: 2016-05-04 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase. Sci.Signal., 9, 2016
6P1C	Transcription antitermination factor Q21, SeMet-derivative Descriptor: CHLORIDE ION, Q protein Authors: Yin, Z, Ebright, R.H. Deposit date: 2019-05-19 Release date: 2019-06-26 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
5CCY	2009 H1N1 PA endonuclease in complex with dTMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE Authors: Kumar, G, White, S.W. Deposit date: 2015-07-02 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
3WI1	P453H/I471T mutant of PB2 middle domain from influenza virus A/Puerto Rico/8/34(H1N1) with m7GTP Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Polymerase basic protein 2 Authors: Tsurumura, T, Yoshida, T, Tsuge, H. Deposit date: 2013-09-04 Release date: 2013-12-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.931 Å) Cite: Conformational Polymorphism of m7GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus Plos One, 8, 2013
4IO9	Crystal structure of compound 4d bound to large ribosomal subunit (50S) from Deinococcus radiodurans Descriptor: (3aS,4R,7R,8S,9S,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,14-trioxo-10-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-8-yl (2R)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate, 23S ribosomal RNA, 50S ribosomal protein L11, ... Authors: Han, S, Marr, E.S. Deposit date: 2013-01-07 Release date: 2013-03-06 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. Bioorg.Med.Chem.Lett., 23, 2013
4IOA	Crystal structure of compound 4e bound to large ribosomal subunit (50S) from Deinococcus radiodurans Descriptor: (3aS,4R,7R,8S,9S,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,14-trioxo-10-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-8-yl (2R)-2-[4-(acetylamino)phenyl]-2,3-dihydro-1H-pyrrole-1-carboxylate, 23S ribosomal RNA, 50S ribosomal protein L11, ... Authors: Han, S, Marr, E.S. Deposit date: 2013-01-07 Release date: 2013-03-06 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. Bioorg.Med.Chem.Lett., 23, 2013
8KCA	Crystal structure of DDX53 helicase domain Descriptor: Probable ATP-dependent RNA helicase DDX53 Authors: Park, S, Yang, J.B, Jung, H.S, Kim, H.Y. Deposit date: 2023-08-06 Release date: 2023-08-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structural insight into crystal structure of helicase domain of DDX53. Biochem.Biophys.Res.Commun., 677, 2023
4IOC	Crystal structure of compound 4f bound to large ribosomal subunit (50S) from Deinococcus radiodurans Descriptor: (3aS,4R,7R,8S,9S,10R,11R,13R,15S,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,14-trioxo-10-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-8-yl (2R)-4,4-dimethyl-2-(pyridin-3-yl)pyrrolidine-1-carboxylate, 23S ribosomal RNA, 50S ribosomal protein L11, ... Authors: Han, S, Marr, E.S. Deposit date: 2013-01-07 Release date: 2013-03-06 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. Bioorg.Med.Chem.Lett., 23, 2013
5CL0	2009 H1N1 PA endonuclease in complex with rUMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE Authors: Kumar, G, White, S.W. Deposit date: 2015-07-15 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5CGV	2009 H1N1 PA endonuclease in complex with L-742,001 Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, GLYCEROL, MANGANESE (II) ION, ... Authors: Kumar, G, White, S.W. Deposit date: 2015-07-09 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
8OPG	Virus-like Particle based on PVY coat protein with dC79 deletion with RNA-free helical architecture Descriptor: Genome polyprotein (Fragment) Authors: Kavcic, L, Kezar, A, Podobnik, M. Deposit date: 2023-04-07 Release date: 2024-01-24 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y. Commun Chem, 7, 2024
5D42	2009 H1N1 PA endonuclease mutant F105S in complex with dTMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE Authors: Kumar, G, White, S.W. Deposit date: 2015-08-07 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5DEB	2009 H1N1 PA endonuclease mutant E119D in complex with rUMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE Authors: Kumar, G, White, S.W. Deposit date: 2015-08-25 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5D8U	2009 H1N1 PA endonuclease mutant E119D in complex with L-742,001 Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase acidic protein Authors: Kumar, G, White, S.W. Deposit date: 2015-08-18 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5D4G	2009 H1N1 PA endonuclease mutant F105S in complex with rUMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE Authors: Kumar, G, White, S.W. Deposit date: 2015-08-07 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
7QQR	SpCas9 bound to AAVS1 off-target5 DNA substrate Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target5 non-target strand, AAVS1 off-target5 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQV	SpCas9 bound to FANCF off-target3 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target3 non-target strand, FANCF off-target3 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR5	SpCas9 bound to FANCF off-target6 DNA substrate Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target6 non-target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-17 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQP	SpCas9 bound to AAVS1 off-target3 DNA substrate Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target3 non-target strand, AAVS1 off-target3 target strand, ... Authors: Pacesa, M, JInek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQS	SpCas9 bound to FANCF on-target DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQO	SpCas9 bound to AAVS1 off-target1 DNA substrate Descriptor: AAVS1 off-target1 non-target strand, AAVS1 off-target1 target strand, AAVS1 sgRNA, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQQ	SpCas9 bound to AAVS1 off-target4 DNA substrate Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target4 non-target strand, AAVS1 off-target4 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQU	SpCas9 bound to FANCF off-target2 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022

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