3RH1
 
 | | X-ray Structure of a cis-proline (P114) to alanine variant of Ribonuclease A | | Descriptor: | CHLORIDE ION, Ribonuclease pancreatic | | Authors: | Merlino, A, Balsamo, A, Mazzarella, L, Sica, F. | | Deposit date: | 2011-04-11 | | Release date: | 2012-02-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.
Biochimie, 94, 2012
|
|
1JN4
 | | The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine | | Descriptor: | ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE, Pancreatic Ribonuclease A | | Authors: | Jardine, A.M, Leonidas, D.D, Jenkins, J.L, Park, C, Raines, R.T, Acharya, K.R, Shapiro, R. | | Deposit date: | 2001-07-23 | | Release date: | 2003-06-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin
Biochemistry, 40, 2001
|
|
6XHE
 | | Structure of beta-prolinyl 5'-O-adenosine phosphoramidate | | Descriptor: | 5'-O-[(S)-[(3S)-3-carboxypyrrolidin-1-yl](hydroxy)phosphoryl]adenosine, ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | | Authors: | Pallan, P.S, Egli, M. | | Deposit date: | 2020-06-18 | | Release date: | 2021-03-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6XHD
 | | Structure of Prolinyl-5'-O-adenosine phosphoramidate | | Descriptor: | (2~{S})-1-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]pyrrolidine-2-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, ... | | Authors: | Pallan, P.S, Egli, M. | | Deposit date: | 2020-06-18 | | Release date: | 2021-03-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6XHF
 | | Structure of Phenylalanyl-5'-O-adenosine phosphoramidate | | Descriptor: | (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, Ribonuclease pancreatic | | Authors: | Pallan, P.S, Egli, M. | | Deposit date: | 2020-06-18 | | Release date: | 2021-03-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6XHC
 | | Structure of glycinyl 5'-O-adenosine phosphoramidate | | Descriptor: | 2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]ethanoic acid, Ribonuclease pancreatic | | Authors: | Pallan, P.S, Egli, M. | | Deposit date: | 2020-06-18 | | Release date: | 2020-12-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
3RSD
 | |
7PNI
 | |
4SRN
 | | STRUCTURAL CHANGES THAT ACCOMPANY THE REDUCED CATALYTIC EFFICIENCY OF TWO SEMISYNTHETIC RIBONUCLEASE ANALOGS | | Descriptor: | RIBONUCLEASE A, SULFATE ION | | Authors: | deMel, V.S.J, Martin, P.D, Doscher, M.S, Edwards, B.F.P. | | Deposit date: | 1991-05-20 | | Release date: | 1994-12-20 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs.
J.Biol.Chem., 267, 1992
|
|
1R4Y
 | | SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN | | Descriptor: | Ribonuclease alpha-sarcin | | Authors: | Garcia-Mayoral, M.F, Garcia-Ortega, L, Lillo, M.P, Santoro, J, Martinez Del Pozo, A, Gavilanes, J.G, Rico, M, Bruix, M. | | Deposit date: | 2003-10-09 | | Release date: | 2004-04-06 | | Last modified: | 2021-10-27 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the noncytotoxic {alpha}-sarcin mutant {Delta}(7-22): The importance of the native conformation of peripheral loops for activity.
Protein Sci., 13, 2004
|
|
1B6V
 | | CRYSTAL STRUCTURE OF A HYBRID BETWEEN RIBONUCLEASE A AND BOVINE SEMINAL RIBONUCLEASE | | Descriptor: | RIBONUCLEASE | | Authors: | Vatzaki, E.H, Allen, S.C, Leonidas, D.D, Acharya, K.R. | | Deposit date: | 1999-01-18 | | Release date: | 1999-06-15 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution.
Eur.J.Biochem., 260, 1999
|
|
1A5Q
 | | P93A VARIANT OF BOVINE PANCREATIC RIBONUCLEASE A | | Descriptor: | RIBONUCLEASE A, SULFATE ION | | Authors: | Pearson, M.A, Karplus, P.A, Dodge, R.W, Laity, J.H, Scheraga, H.A. | | Deposit date: | 1998-02-17 | | Release date: | 1998-05-27 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.
Protein Sci., 7, 1998
|
|
8C3B
 | | X-ray structure of RNase A upon reaction with a Ruthenium(II)-arene Complexed with Glycosylated Carbene Ligands (5) | | Descriptor: | (1,3-dimethyl-2~{H}-imidazol-2-yl)-oxidanyl-oxidanylidene-ruthenium, (1,3-dimethylimidazol-1-ium-2-yl)-tetrakis(oxidanyl)ruthenium, (1,3-dimethylimidazol-1-ium-2-yl)-tris(oxidanyl)ruthenium, ... | | Authors: | Ferraro, G, Merlino, A. | | Deposit date: | 2022-12-23 | | Release date: | 2024-01-10 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Ruthenium(II)–Arene Complexes with Glycosylated NHC-Carbene Co-Ligands: Synthesis, Hydrolytic Behavior, and Binding to Biological Molecules
Organometallics, 42, 2023
|
|
1C8W
 | | THR45GLY VARIANT OF RIBONUCLEASE A | | Descriptor: | ACETATE ION, CHLORIDE ION, PROTEIN (Ribonuclease A) | | Authors: | Kelemen, B.R, Sweeney, R.T, Schultz, L.W, Raines, R.T. | | Deposit date: | 1999-07-30 | | Release date: | 2002-05-01 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Excavating an active site: the nucleobase specificity of ribonuclease A.
Biochemistry, 39, 2000
|
|
1A5P
 | | C[40,95]A VARIANT OF BOVINE PANCREATIC RIBONUCLEASE A | | Descriptor: | RIBONUCLEASE A, SULFATE ION | | Authors: | Pearson, M.A, Karplus, P.A, Dodge, R.W, Laity, J.H, Scheraga, H.A. | | Deposit date: | 1998-02-17 | | Release date: | 1998-05-27 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.
Protein Sci., 7, 1998
|
|
3LXO
 | | The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate | | Descriptor: | Ribonuclease pancreatic, THYMIDINE-3'-PHOSPHATE | | Authors: | Doucet, N, Jayasundera, T.B, Simonovic, M, Loria, J.P. | | Deposit date: | 2010-02-25 | | Release date: | 2010-04-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.549 Å) | | Cite: | The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding.
Proteins, 78, 2010
|
|
8RSA
 | |
3RSK
 | |
4RTE
 | |
3RID
 | | X-ray structure of the C-terminal swapped dimer of P114A variant of Ribonuclease A | | Descriptor: | 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, PHOSPHATE ION, Ribonuclease pancreatic | | Authors: | Merlino, A, Balsamo, A, Mazzarella, L, Sica, F. | | Deposit date: | 2011-04-13 | | Release date: | 2012-02-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.
Biochimie, 94, 2012
|
|
4G90
 | | Crystal structure of Ribonuclease A in complex with 5e | | Descriptor: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | | Authors: | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | | Deposit date: | 2012-07-23 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
|
|
4G8V
 | | Crystal structure of Ribonuclease A in complex with 5a | | Descriptor: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | | Authors: | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | | Deposit date: | 2012-07-23 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
|
|
4G8Y
 | | Crystal structure of Ribonuclease A in complex with 5b | | Descriptor: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | | Authors: | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | | Deposit date: | 2012-07-23 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
|
|
2RNS
 | | REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES | | Descriptor: | RIBONUCLEASE S, SULFATE ION | | Authors: | Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M. | | Deposit date: | 1992-02-19 | | Release date: | 1994-01-31 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures.
Biochemistry, 31, 1992
|
|
4RSD
 | | STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A | | Descriptor: | ACETATE ION, CHLORIDE ION, RIBONUCLEASE A | | Authors: | Schultz, L.W, Quirk, D.J, Raines, R.T. | | Deposit date: | 1998-02-05 | | Release date: | 1998-07-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
|
|
