PDB: 187 resultsInfo pagesStatus searchChemie searchBIRD

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1B2Z	DELETION OF A BURIED SALT BRIDGE IN BARNASE Descriptor: PROTEIN (BARNASE), ZINC ION Authors: Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. Deposit date: 1998-12-03 Release date: 1998-12-09 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.03 Å) Cite: A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
1B2X	BARNASE WILDTYPE STRUCTURE AT PH 7.5 FROM A CRYO_COOLED CRYSTAL AT 100K Descriptor: PROTEIN (BARNASE), ZINC ION Authors: Harrison, P, Vaughan, C.K, Buckle, A.M, Fersht, A.R. Deposit date: 1998-12-03 Release date: 1998-12-09 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
1BNS	STRUCTURAL STUDIES OF BARNASE MUTANTS Descriptor: BARNASE Authors: Chen, Y.W. Deposit date: 1994-04-11 Release date: 1994-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants. J.Mol.Biol., 234, 1993
1BSE	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BRI	BARNASE MUTANT WITH ILE 76 REPLACED BY ALA Descriptor: BARNASE Authors: Cramer, P.C, Buckle, A, Fersht, A. Deposit date: 1995-03-09 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
1BNR	BARNASE Descriptor: BARNASE (G SPECIFIC ENDONUCLEASE) Authors: Bycroft, M. Deposit date: 1995-03-31 Release date: 1995-07-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy. Biochemistry, 30, 1991
1BNF	BARNASE T70C/S92C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BSA	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BNJ	BARNASE WILDTYPE STRUCTURE AT PH 9.0 Descriptor: BARNASE Authors: Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M. Deposit date: 1995-05-17 Release date: 1995-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BRK	BARNASE MUTANT WITH ILE 96 REPLACED BY ALA Descriptor: BARNASE, ZINC ION Authors: Cramer, P.C, Buckle, A, Fersht, A. Deposit date: 1995-03-09 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
1BU4	RIBONUCLEASE 1 COMPLEX WITH 2'GMP Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 Authors: Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J. Deposit date: 1998-09-11 Release date: 1999-02-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conserved water molecules in a large family of microbial ribonucleases. Proteins, 36, 1999
1BUJ	STRUCTURE OF BINASE IN SOLUTION Descriptor: PROTEIN (BINASE) Authors: Reibarkh, M.Y, Nolde, D.E, Vasilieva, L.I, Arseniev, A.S. Deposit date: 1998-09-04 Release date: 1998-09-09 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Three-dimensional structure of binase in solution. FEBS Lett., 431, 1998
1BNE	BARNASE A43C/S80C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BSD	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BNG	BARNASE S85C/H102C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BOX	N39S MUTANT OF RNASE SA FROM STREPTOMYCES AUREOFACIENS Descriptor: GUANYL-SPECIFIC RIBONUCLEASE SA Authors: Hebert, E.J, Giletto, A, Sevcik, J, Urbanikova, L, Wilson, K.S, Dauter, Z, Pace, C.N. Deposit date: 1998-08-07 Release date: 1999-12-29 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Contribution of a conserved asparagine to the conformational stability of ribonucleases Sa, Ba, and T1. Biochemistry, 37, 1998
1BRG	CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE Descriptor: BARNASE, ZINC ION Authors: Chen, Y.W, Fersht, A.R, Henrick, K. Deposit date: 1994-03-30 Release date: 1994-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystallographic analysis of Phe-->Leu substitution in the hydrophobic core of barnase. Acta Crystallogr.,Sect.D, 51, 1995
1BSB	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BRN	SUBSITE BINDING IN AN RNASE: STRUCTURE OF A BARNASE-TETRANUCLEOTIDE COMPLEX AT 1.76 ANGSTROMS RESOLUTION Descriptor: DNA (5'-D(*CP*GP*AP*C)-3'), PROTEIN (BARNASE (E.C.3.1.27.-)) Authors: Buckle, A.M, Fersht, A.R. Deposit date: 1993-11-17 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution. Biochemistry, 33, 1994
1BSC	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
7MRX	Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/C82A Descriptor: Barstar, Ribonuclease Authors: Caro, J.A, Smith, J, Wand, A.J. Deposit date: 2021-05-10 Release date: 2022-05-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Conformational entropy and protein affinity To Be Published
6PQK	Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/S59C/A67C/C82A Descriptor: 1,2-ETHANEDIOL, Barstar, PHOSPHATE ION, ... Authors: Caro, J.A, Djanto, V, Wand, A.J. Deposit date: 2019-07-09 Release date: 2020-07-15 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Targeting conformational entropy to modulate binding affinity To Be Published
3DA7	A conformationally strained, circular permutant of barnase Descriptor: Barnase circular permutant, Barstar Authors: Mitrousis, G, Butler, J, Loh, S.N, Cingolani, G. Deposit date: 2008-05-28 Release date: 2009-04-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and thermodynamic analysis of a conformationally strained circular permutant of barnase. Biochemistry, 48, 2009
2ZA4	Crystal Structural Analysis of Barnase-barstar Complex Descriptor: Barstar, CHLORIDE ION, Ribonuclease Authors: Urakubo, Y, Ikura, T, Ito, N. Deposit date: 2007-10-01 Release date: 2008-05-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Crystal structural analysis of protein-protein interactions drastically destabilized by a single mutation Protein Sci., 17, 2008
1X1Y	Water-mediate interaction at aprotein-protein interface Descriptor: Barstar, Ribonuclease Authors: Ikura, T, Urakubo, Y, Ito, N. Deposit date: 2005-04-15 Release date: 2005-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Water-mediated interaction at a protein-protein interface Chem.Phys., 307, 2004

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