PDB: 223790 resultsInfo pagesStatus searchChemie searchBIRD

---

9F4K	UP1 in complex with ZINC72259689 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(cyclobutylmethyl)-1,3-dimethyl-pyrazole-4-carboxamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9AZI	NMR solution structure of cell-permeant miniature protein ZF5.3 Descriptor: Designed Zinc finger protein 5.3, ZINC ION Authors: Giudice, J.A, Kelly, M, Schepartz, A. Deposit date: 2024-03-11 Release date: 2024-05-01 Method: SOLUTION NMR Cite: Structural and mechanistic basis for efficient endosomal escape by designed mini-proteins To be published
9F4G	UP1 in complex with Z1373445602 Descriptor: 4-(3-fluoranylpyridin-2-yl)-1-methyl-piperazin-2-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4T	UP1 in complex with EN300-805013 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(4-methoxyphenyl)glycinamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9AVW	Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin Descriptor: SULFATE ION, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ... Authors: Michel, M.A, Scutts, S, Komander, D. Deposit date: 2024-03-05 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (1.747 Å) Cite: Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin To be published
8XHA	Crystal structure of alpha-Oxoamine Synthase Alb29 with PLP cofactor and L-glutamate Descriptor: 8-amino-7-oxononanoate synthase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE Authors: Xu, M.J, Zhang, D.K. Deposit date: 2023-12-17 Release date: 2024-05-01 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structural and mechanistic investigations on CC bond forming alpha-oxoamine synthase allowing L-glutamate as substrate. Int.J.Biol.Macromol., 268, 2024
8XCJ	Open State of central tail fiber of bacteriophage lambda upon binding to LamB (gpJ713-LamB complex) Descriptor: Maltoporin, Tip attachment protein J Authors: Ge, X.F, Wang, J.W. Deposit date: 2023-12-09 Release date: 2024-05-01 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Structural mechanism of bacteriophage lambda tail's interaction with the bacterial receptor. Nat Commun, 15, 2024
9F4S	UP1 in complex with Z56880342 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-ethyl-N'-(5-methyl-1,2-oxazol-3-yl)urea Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F50	UP1 in complex with Z906021418 Descriptor: 5-chloro-2-(propan-2-yl)pyrimidine-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9B0B	Structure of Optineurin bound to HOIP NZF1 domain Descriptor: E3 ubiquitin-protein ligase RNF31, Optineurin, TETRAETHYLENE GLYCOL, ... Authors: Michel, M.A, Scutts, S, Komander, D. Deposit date: 2024-03-11 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Linkage and substrate specificity conferred by NZF ubiquitin binding domains To Be Published
9F51	UP1 in complex with Z608065044 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N},~{N}-dimethyl-1~{H}-pyrazole-4-sulfonamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5F	UP1 in complex with Z992569480 Descriptor: (3R)-N-methyl-1-(pyridazin-3-yl)piperidin-3-amine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9B9M	Crystal structure of iron-bound FlcD from Pseudomonas aeruginosa Descriptor: FE (II) ION, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Authors: Walker, M.E, Grove, T.L, Li, B, Redinbo, M.R. Deposit date: 2024-04-02 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structural Basis for Methine Excision by a Heme Oxygenase-like Enzyme Acs Cent.Sci., 2024
9ATW	Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus Descriptor: Phenol-soluble modulin alpha 1 peptide Authors: Hansen, K.H, Byeon, C.H, Liu, Q, Drace, T, Boesen, T, Conway, J.F, Andreasen, M, Akbey, U. Deposit date: 2024-02-27 Release date: 2024-08-07 Last modified: 2024-08-14 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus Proceedings of the National Academy of Sciences of the United States of America, 2024
9F5G	UP1 in complex with EN300-115958 Descriptor: 1-[(2R)-1-(methanesulfonyl)pyrrolidin-2-yl]methanamine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9BIV	Crystal Structure of Ubc13 with a New Active Site Loop Conformation Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Farraj, R.A, Edwards, R.A, Glover, J.N.M. Deposit date: 2024-04-24 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal Structure of Ubc13 with a New Active Site Loop Conformation To Be Published
9BBL	THF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition Descriptor: Isoform Tau-F of Microtubule-associated protein tau Authors: Duan, P, El Mammeri, N. Deposit date: 2024-04-06 Release date: 2024-05-08 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Milligram-scale assembly and NMR fingerprint of tau fibrils adopting the Alzheimer's disease fold. J.Biol.Chem., 300, 2024
8Z75	The structure of non-activated thiocyanate dehydrogenase from Pelomicrobium methylotrophicum (pmTcDH) Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... Authors: Varfolomeeva, L.A, Solovieva, A.Y, Shipkov, N.S, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O. Deposit date: 2024-04-19 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The structure of non-activated thiocyanate dehydrogenase from Pelomicrobium methylotrophicum (pmTcDH) To Be Published
9F4H	UP1 in complex with Z106579662 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4U	UP1 in complex with Z111529496 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(1~{H}-benzimidazol-2-ylmethyl)-2-methoxy-ethanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F54	UP1 in complex with EN300-197154 Descriptor: 1-methyl-3-[(3R)-piperidin-3-yl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5K	UP1 in complex with Z33546965 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(2-azanyl-2-oxidanylidene-ethyl)-4-methoxy-benzamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-29 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9B33	Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA Descriptor: CALCIUM ION, Concanavalin V, ZINC ION Authors: Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. Deposit date: 2024-03-18 Release date: 2024-05-22 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
8Y1J	Structure of the pyridoxal 5'-phosphate-dependent (PLP) threonine deaminase ilvA1 from Pseudomonas aeruginosa PAO1 Descriptor: 2-KETOBUTYRIC ACID, L-threonine dehydratase Authors: Jia, H, Bartlam, M. Deposit date: 2024-01-24 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and function of the pyridoxal 5'-phosphate-dependent (PLP) threonine deaminase IlvA1 from Pseudomonas aeruginosa PAO1. Biochem.Biophys.Res.Commun., 704, 2024
9EO2	X-ray structure of the adduct formed upon reaction of picoplatin with lysozyme (structure B) Descriptor: ACETATE ION, GLYCEROL, Lysozyme C, ... Authors: Ferraro, G, Merlino, A. Deposit date: 2024-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A. Dalton Trans, 53, 2024

<599600601602603604605606607608609610611612613614>