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6RXA
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BU of 6rxa by Molmil
EDDS lyase variant D290M/Y320M with bound formate
Descriptor: Argininosuccinate lyase, FORMIC ACID, GLYCEROL, ...
Authors:Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H.
Deposit date:2019-06-07
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.
Angew.Chem.Int.Ed.Engl., 59, 2020
6S7Z
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BU of 6s7z by Molmil
Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator N-(5-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
Descriptor: FORMIC ACID, Fumarate hydratase class II, MAGNESIUM ION, ...
Authors:Whitehouse, A.J, Libardo, M.D, Kasbekar, M, Brear, P, Fischer, G, Thomas, C.J, Barry, C.E, Boshoff, H.I, Coyne, A.G, Abell, C.
Deposit date:2019-07-07
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Targeting of Fumarate Hydratase fromMycobacterium tuberculosisUsing Allosteric Inhibitors with a Dimeric-Binding Mode.
J.Med.Chem., 62, 2019
6U4O
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BU of 6u4o by Molmil
Crystal structure of recombinant class II fumarase from Schistosoma mansoni
Descriptor: (2S)-2-hydroxybutanedioic acid, ACETATE ION, Fumarate hydratase, ...
Authors:Cardoso, I.A, Nonato, M.C.
Deposit date:2019-08-26
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Characterization of class II fumarase from Schistosoma mansoni provides the molecular basis for selective inhibition.
Int.J.Biol.Macromol., 175, 2021

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