3DP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dp9 by Molmil](/molmil-images/mine/3dp9) | Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin A | Descriptor: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, IODIDE ION, MTA/SAH nucleosidase | Authors: | Ho, M, Gutierrez, J.A, Crowder, T, Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. | Deposit date: | 2008-07-07 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing. Nat.Chem.Biol., 5, 2009
|
|
3DQ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dq6 by Molmil](/molmil-images/mine/3dq6) | |
3DQL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dql by Molmil](/molmil-images/mine/3dql) | |
3DTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dtq by Molmil](/molmil-images/mine/3dtq) | |
3DRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3drb by Molmil](/molmil-images/mine/3drb) | Crystal structure of Human Brain-type Creatine Kinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Creatine kinase B-type, MAGNESIUM ION | Authors: | Moon, J.H, Bong, S.M, Hwang, K.Y, Chi, Y.M. | Deposit date: | 2008-07-11 | Release date: | 2009-03-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural studies of human brain-type creatine kinase complexed with the ADP-Mg2+-NO3- -creatine transition-state analogue complex Febs Lett., 582, 2008
|
|
3DUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3duk by Molmil](/molmil-images/mine/3duk) | |
3DT2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dt2 by Molmil](/molmil-images/mine/3dt2) | |
3B0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b0x by Molmil](/molmil-images/mine/3b0x) | K263A mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Nakane, S, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-06-17 | Release date: | 2012-05-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
|
|
3B1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b1x by Molmil](/molmil-images/mine/3b1x) | Crystal structure of an S. thermophilus NFeoB E66A mutant bound to GMPPNP | Descriptor: | Ferrous iron uptake transporter protein B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Ash, M.R, Maher, M.J, Guss, J.M, Jormakka, M. | Deposit date: | 2011-07-15 | Release date: | 2011-11-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB Acta Crystallogr.,Sect.D, 67, 2011
|
|
3B0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b0p by Molmil](/molmil-images/mine/3b0p) | tRNA-dihydrouridine synthase from Thermus thermophilus | Descriptor: | FLAVIN MONONUCLEOTIDE, tRNA-dihydrouridine synthase | Authors: | Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I. | Deposit date: | 2011-06-12 | Release date: | 2011-12-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular basis of dihydrouridine formation on tRNA Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3B0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b0h by Molmil](/molmil-images/mine/3b0h) | Assimilatory nitrite reductase (Nii4) from tobbaco root | Descriptor: | CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ... | Authors: | Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. | Deposit date: | 2011-06-09 | Release date: | 2012-02-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.306 Å) | Cite: | Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high resolution structures Protein Sci., 21, 2012
|
|
3ENS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ens by Molmil](/molmil-images/mine/3ens) | |
3EO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eo6 by Molmil](/molmil-images/mine/3eo6) | |
3EHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ehg by Molmil](/molmil-images/mine/3ehg) | |
3EHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ehn by Molmil](/molmil-images/mine/3ehn) | BT1043 with N-acetyllactosamine | Descriptor: | SusD homolog, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Smith, T.J, Koropatkin, N.M. | Deposit date: | 2008-09-13 | Release date: | 2009-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont. Biochemistry, 48, 2009
|
|
3E3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e3k by Molmil](/molmil-images/mine/3e3k) | Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA (butane-1,2,4-tricarboxylate without nickel form) | Descriptor: | (2R)-butane-1,2,4-tricarboxylic acid, ACETATE ION, CHLORIDE ION, ... | Authors: | Cherrier, M.V, Cavazza, C, Bochot, C, Lemaire, D, Fontecilla-Camps, J.C. | Deposit date: | 2008-08-07 | Release date: | 2008-09-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA Biochemistry, 47, 2008
|
|
3EIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eiu by Molmil](/molmil-images/mine/3eiu) | A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A1Ao ATP synthase | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ADENOSINE-5'-TRIPHOSPHATE, V-type ATP synthase beta chain | Authors: | Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G. | Deposit date: | 2008-09-17 | Release date: | 2009-02-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.43 Å) | Cite: | A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(O) ATP synthase J.Struct.Biol., 166, 2009
|
|
3E5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e5t by Molmil](/molmil-images/mine/3e5t) | Crystal Structure Analysis of FP611 | Descriptor: | Red fluorescent protein eqFP611 | Authors: | Nar, H, Nienhaus, K, Nienhaus, U, Wiedenmann, J. | Deposit date: | 2008-08-14 | Release date: | 2008-09-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611. J.Am.Chem.Soc., 130, 2008
|
|
3E64
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e64 by Molmil](/molmil-images/mine/3e64) | Fragment based discovery of JAK-2 inhibitors | Descriptor: | 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide, Tyrosine-protein kinase JAK2 | Authors: | Antonysamy, S, Fang, W, Hirst, G, Park, F, Russell, M, Smyth, L, Sprengeler, P, Stappenbeck, F, Steensma, R, Thompson, D.A, Wilson, M, Wong, M, Zhang, A, Zhang, F. | Deposit date: | 2008-08-14 | Release date: | 2008-10-14 | Last modified: | 2012-02-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-based discovery of JAK-2 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
|
|
3EKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ekq by Molmil](/molmil-images/mine/3ekq) | Crystal structure of inhibitor saquinavir (SQV) in complex with multi-drug resistant HIV-1 protease (L63P/V82T/I84V) (referred to as ACT in paper) | Descriptor: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, PHOSPHATE ION, Protease | Authors: | Prabu-Jeyabalan, M, King, N.M, Schiffer, C.A, Nalivaika, E. | Deposit date: | 2008-09-19 | Release date: | 2009-09-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease. Acs Chem.Biol., 7, 2012
|
|
3E7C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e7c by Molmil](/molmil-images/mine/3e7c) | Glucocorticoid Receptor LBD bound to GSK866 | Descriptor: | 5-amino-N-[(2S)-2-({[(2,6-dichlorophenyl)carbonyl](ethyl)amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide, GLYCEROL, Glucocorticoid receptor, ... | Authors: | Madauss, K.P, Williams, S.P, Mclay, I, Stewart, E.L, Bledsoe, R.K. | Deposit date: | 2008-08-18 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist. Bioorg.Med.Chem.Lett., 18, 2008
|
|
3E86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e86 by Molmil](/molmil-images/mine/3e86) | |
3E8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e8f by Molmil](/molmil-images/mine/3e8f) | |
3ELM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3elm by Molmil](/molmil-images/mine/3elm) | Crystal Structure of MMP-13 Complexed with Inhibitor 24f | Descriptor: | (2R)-({[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonyl}amino){1-[(1-methylethoxy)carbonyl]piperidin-4-yl}ethanoic acid, CALCIUM ION, Collagenase 3, ... | Authors: | Kulathila, R, Monovich, L, Koehn, J. | Deposit date: | 2008-09-22 | Release date: | 2009-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13 J.Med.Chem., 52, 2009
|
|
3E97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e97 by Molmil](/molmil-images/mine/3e97) | |