1O7F
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![BU of 1o7f by Molmil](/molmil-images/mine/1o7f) | CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF EPAC2 | Descriptor: | CAMP-DEPENDENT RAP1 GUANINE-NUCLEOTIDE EXCHANGE FACTOR | Authors: | Rehmann, H, Prakash, B, Wolf, E, Rueppel, A, De Rooij, J, Bos, J.L, Wittinghofer, A. | Deposit date: | 2002-11-04 | Release date: | 2002-11-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Regulation of the Camp-Binding Domains of Epac2 Nat.Struct.Biol., 10, 2002
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3CVL
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![BU of 3cvl by Molmil](/molmil-images/mine/3cvl) | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphofructokinase (PFK) PTS1 peptide | Descriptor: | Peroxisome targeting signal 1 receptor PEX5, T. brucei PFK PTS1 peptide Ac-HEELAKL | Authors: | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2008-04-18 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
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3CVQ
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![BU of 3cvq by Molmil](/molmil-images/mine/3cvq) | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (7-SKL) | Descriptor: | GLYCEROL, PTS1 peptide 7-SKL (Ac-SNRWSKL), Peroxisome targeting signal 1 receptor PEX5 | Authors: | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2008-04-18 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
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2HP3
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![BU of 2hp3 by Molmil](/molmil-images/mine/2hp3) | Crystal structure of iminodisuccinate epimerase | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IDS-epimerase, ... | Authors: | Lohkamp, B, Bauerle, B, Rieger, P.G, Schneider, G. | Deposit date: | 2006-07-17 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family. J.Mol.Biol., 362, 2006
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3EM2
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![BU of 3em2 by Molmil](/molmil-images/mine/3em2) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6038 | Descriptor: | 3,6-Bis[(3-morpholinopropionamido)] acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-09-23 | Release date: | 2008-10-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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1C3Q
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![BU of 1c3q by Molmil](/molmil-images/mine/1c3q) | CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM | Descriptor: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, CHLORIDE ION, Hydroxyethylthiazole kinase | Authors: | Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E. | Deposit date: | 1999-07-28 | Release date: | 1999-08-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. Biochemistry, 39, 2000
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1DLI
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![BU of 1dli by Molmil](/molmil-images/mine/1dli) | THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION | Descriptor: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | Authors: | Campbell, R.E, Mosimann, S.C, van de Rijn, I, Tanner, M.E, Strynadka, N.C.J. | Deposit date: | 1999-12-09 | Release date: | 2000-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation. Biochemistry, 39, 2000
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3EQW
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![BU of 3eqw by Molmil](/molmil-images/mine/3eqw) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in small unit cell | Descriptor: | 3,6-Bis{3-[(2R)-(2-ethylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-01 | Release date: | 2008-10-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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1DLJ
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![BU of 1dlj by Molmil](/molmil-images/mine/1dlj) | THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | Authors: | Campbell, R.E, Mosimann, S.C, van de Rijn, I, Tanner, M.E, Strynadka, N.C.J. | Deposit date: | 1999-12-09 | Release date: | 2000-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation. Biochemistry, 39, 2000
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3C9L
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![BU of 3c9l by Molmil](/molmil-images/mine/3c9l) | |
1F6D
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![BU of 1f6d by Molmil](/molmil-images/mine/1f6d) | THE STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE FROM E. COLI. | Descriptor: | CHLORIDE ION, SODIUM ION, UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE, ... | Authors: | Campbell, R.E, Mosimann, S.C, Tanner, M.E, Strynadka, N.C.J. | Deposit date: | 2000-06-21 | Release date: | 2000-12-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases. Biochemistry, 39, 2000
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2IP4
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![BU of 2ip4 by Molmil](/molmil-images/mine/2ip4) | Crystal Structure of Glycinamide Ribonucleotide Synthetase from Thermus thermophilus HB8 | Descriptor: | Phosphoribosylamine--glycine ligase, SULFATE ION | Authors: | Sampei, G, Baba, S, Kanagawa, M, Yanai, H, Ishii, T, Kawai, H, Fukai, Y, Ebihara, A, Nakagawa, N, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-10-11 | Release date: | 2007-10-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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3CVP
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![BU of 3cvp by Molmil](/molmil-images/mine/3cvp) | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (10-SKL) | Descriptor: | 10-SKL PTS1 peptide Ac-GTLSNRASKL, Peroxisome targeting signal 1 receptor PEX5 | Authors: | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2008-04-18 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
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2HP0
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![BU of 2hp0 by Molmil](/molmil-images/mine/2hp0) | Crystal structure of iminodisuccinate epimerase | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2-ETHANEDIOL, IDS-epimerase, ... | Authors: | Lohkamp, B, Bauerle, B, Rieger, P.G, Schneider, G. | Deposit date: | 2006-07-17 | Release date: | 2006-09-12 | Last modified: | 2011-10-19 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family. J.Mol.Biol., 362, 2006
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1EKQ
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![BU of 1ekq by Molmil](/molmil-images/mine/1ekq) | |
3CVN
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![BU of 3cvn by Molmil](/molmil-images/mine/3cvn) | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) PTS1 peptide | Descriptor: | 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor, T. brucei GAPDH PTS1 peptide Ac-DRDAAKL | Authors: | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2008-04-18 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
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1F8F
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![BU of 1f8f by Molmil](/molmil-images/mine/1f8f) | CRYSTAL STRUCTURE OF BENZYL ALCOHOL DEHYDROGENASE FROM ACINETOBACTER CALCOACETICUS | Descriptor: | BENZYL ALCOHOL DEHYDROGENASE, ETHANOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Beauchamp, J.C, Gillooly, D, Warwicker, J, Fewson, C.A, Lapthorn, A.J. | Deposit date: | 2000-06-30 | Release date: | 2003-07-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Benzyl Alcohol Dehydrogenase from Acinetobacter calcoaceticus To be Published
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3E9V
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![BU of 3e9v by Molmil](/molmil-images/mine/3e9v) | Crystal structure of human B-cell Translocation Gene 2 (BTG2) | Descriptor: | 1,2-ETHANEDIOL, Protein BTG2 | Authors: | Sampathkumar, P, Romero, R, Wasserman, S, Hu, S, Maletic, M, Freeman, J, Tarun, G, Atwell, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-08-23 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of human B-cell Translocation Gene 2 (BTG2) To be Published
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3ET8
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![BU of 3et8 by Molmil](/molmil-images/mine/3et8) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6054 | Descriptor: | 3,6-Bis{3-(3-[(3R)-methylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-07 | Release date: | 2008-10-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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3EUM
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![BU of 3eum by Molmil](/molmil-images/mine/3eum) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6066 | Descriptor: | 3,6-Bis[3-(azepan-1-yl)propionamido]acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-10 | Release date: | 2008-10-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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3ERU
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![BU of 3eru by Molmil](/molmil-images/mine/3eru) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6045 | Descriptor: | 3,6-Bis{3-[(2R)-2-methylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-03 | Release date: | 2008-10-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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1FM9
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![BU of 1fm9 by Molmil](/molmil-images/mine/1fm9) | THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES. | Descriptor: | (9cis)-retinoic acid, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, ... | Authors: | Gampe Jr, R.T, Montana, V.G, Lambert, M.H, Miller, A.B, Bledsoe, R.K, Milburn, M.V, Kliewer, S.A, Willson, T.M, Xu, H.E. | Deposit date: | 2000-08-16 | Release date: | 2001-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol.Cell, 5, 2000
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3EUI
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![BU of 3eui by Molmil](/molmil-images/mine/3eui) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in a large unit cell | Descriptor: | 3,6-Bis{3-[(2R)-(2-ethylpiperidino)]propionamido}acridine, 3-[(2R)-2-ethylpiperidin-1-yl]-N-[6-({3-[(2S)-2-ethylpiperidin-1-yl]propanoyl}amino)acridin-3-yl]propanamide, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', ... | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-10 | Release date: | 2008-12-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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3ES0
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![BU of 3es0 by Molmil](/molmil-images/mine/3es0) | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6048 | Descriptor: | 3,6-Bis[3-(4-methylpiperidino)propionamido]acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | Authors: | Campbell, N.H, Parkinson, G, Neidle, S. | Deposit date: | 2008-10-03 | Release date: | 2008-10-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry, 48, 2009
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1FM6
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![BU of 1fm6 by Molmil](/molmil-images/mine/1fm6) | THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES. | Descriptor: | (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... | Authors: | Gampe Jr, R.T, Montana, V.G, Lambert, M.H, Miller, A.B, Bledsoe, R.K, Milburn, M.V, Kliewer, S.A, Willson, T.M, Xu, H.E. | Deposit date: | 2000-08-16 | Release date: | 2001-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol.Cell, 5, 2000
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