6MVW
| NavAb voltage-gated sodium channel, I217C/F203W | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-28 | Release date: | 2018-12-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | Fenestrations control resting-state block of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6MIE
| Solution NMR structure of the KCNQ1 voltage-sensing domain | Descriptor: | Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R. | Deposit date: | 2018-09-19 | Release date: | 2020-03-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, 2020
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6MWB
| NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206A | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ... | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb. J. Gen. Physiol., 151, 2019
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6MWD
| NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206S | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ... | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.327 Å) | Cite: | Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb. J. Gen. Physiol., 151, 2019
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6MVY
| NavAb voltage-gated sodium channel, residues 1-226, crystallized in the presence of Class 1B Anti-arrhythmic drug Lidocaine | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, SULFATE ION | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-28 | Release date: | 2018-12-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Fenestrations control resting-state block of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6MWA
| NavAb Voltage-gated Sodium Channel, residues 1-239 | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ... | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb. J. Gen. Physiol., 151, 2019
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6MVX
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6MWG
| NavAb Voltage-gated Sodium Channel, residues 1-239, with mutation T206V | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ... | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb. J. Gen. Physiol., 151, 2019
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6N4Q
| CryoEM structure of Nav1.7 VSD2 (actived state) in complex with the gating modifier toxin ProTx2 | Descriptor: | Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ... | Authors: | Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M. | Deposit date: | 2018-11-20 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell, 176, 2019
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6MVV
| NavAb voltage-gated sodium channel, I217C/F203A | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION | Authors: | Lenaeus, M.J, Catterall, W.A. | Deposit date: | 2018-10-28 | Release date: | 2018-12-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Fenestrations control resting-state block of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N4R
| CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2 | Descriptor: | Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ... | Authors: | Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M. | Deposit date: | 2018-11-20 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell, 176, 2019
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6NQ2
| Cryo-EM structure of human TPC2 channel in the ligand-bound closed state | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | Authors: | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-03-27 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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6NQ1
| Cryo-EM structure of human TPC2 channel in the apo state | Descriptor: | Two pore calcium channel protein 2 | Authors: | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-03-27 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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6NQ0
| Cryo-EM structure of human TPC2 channel in the ligand-bound open state | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | Authors: | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-03-27 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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8J7F
| ion channel | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... | Authors: | Chen, H.W, Chen, H.W. | Deposit date: | 2023-04-27 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | structure of ion channel To Be Published
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8H9O
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8H9W
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8H9X
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8HA1
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8H9Y
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8HA2
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7TDF
| AtTPC1 D454N with 1 mM EDTA state I | Descriptor: | Two pore calcium channel protein 1 | Authors: | Dickinson, M.S, Stroud, R.M. | Deposit date: | 2021-12-31 | Release date: | 2022-02-02 | Last modified: | 2022-03-09 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TBG
| AtTPC1 D454N with 1 mM Ca2+ | Descriptor: | CALCIUM ION, SODIUM ION, Two pore calcium channel protein 1 | Authors: | Dickinson, M.S, Stroud, R.M. | Deposit date: | 2021-12-22 | Release date: | 2022-02-02 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TDE
| AtTPC1 DDE mutant with 1 mM Ca2+ | Descriptor: | Two pore calcium channel protein 1 | Authors: | Dickinson, M.S, Stroud, R.M. | Deposit date: | 2021-12-31 | Release date: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TDD
| AtTPC1 D454N-EDTA state II | Descriptor: | Two pore calcium channel protein 1 | Authors: | Dickinson, M.S, Stroud, R.M. | Deposit date: | 2021-12-30 | Release date: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
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