PDB: 81877 resultsInfo pagesStatus searchChemie searchBIRD

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3W1Q	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2 Descriptor: 5-(3,3-dimethylbutyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-20 Release date: 2013-11-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2 To be Published
2HO2	Structure of human FE65-WW domain in complex with hMena peptide. Descriptor: Amyloid beta A4 protein-binding family B member 1, GLYCEROL, Protein enabled homolog Authors: Meiyappan, M, Birrane, G, Ladias, J.A. Deposit date: 2006-07-13 Release date: 2007-07-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Structural Basis for Polyproline Recognition by the FE65 WW Domain. J.Mol.Biol., 372, 2007
2I9F	Structure of the equine arterivirus nucleocapsid protein Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... Authors: Deshpande, A, Wang, S, Walsh, M, Dokland, T. Deposit date: 2006-09-05 Release date: 2007-05-01 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement. Acta Crystallogr.,Sect.D, 63, 2007
4UVR	Binding mode, selectivity and potency of N-indolyl-oxopyridinyl-4- amino-propanyl-based inhibitors targeting Trypanosoma cruzi CYP51 Descriptor: Nalpha-{4-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-fluorobenzoyl}-N-pyridin-4-yl-D-tryptophanamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-DEMETHYLASE, ... Authors: Vieira, D.F, Choi, J.Y, Calvet, C.M, Gut, J, Kellar, D, Siqueira-Neto, J.L, Johnston, J.B, McKerrow, J.H, Roush, W.R, Podust, L.M. Deposit date: 2014-08-08 Release date: 2014-11-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Binding Mode and Potency of N-Indolyl-Oxopyridinyl-4-Amino-Propanyl-Based Inhibitors Targeting Trypanosoma Cruzi Cyp51 J.Med.Chem., 57, 2014
6QIH	Pancreatic Bovine Trypsin with a boronic acid inhibitor Descriptor: CALCIUM ION, Cationic trypsin, DI(HYDROXYETHYL)ETHER, ... Authors: Santos-Silva, T, Correia, H.D. Deposit date: 2019-01-18 Release date: 2020-02-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Pancreatic Bovine Trypsin with a boronic acid inhibitor To Be Published
5V0M	SeMet crystal structure of the Neisseria meningitidis non-core minor pilin PilV in the monoclinic form Descriptor: GLYCEROL, Type IV pilin protein Authors: Kolappan, S, Craig, L. Deposit date: 2017-02-28 Release date: 2018-02-28 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.407 Å) Cite: Crystal structure of PilV from Neisseria meningitidis To Be Published
3W1M	Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-bromoorotate Descriptor: 5-bromo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A. Deposit date: 2012-11-16 Release date: 2013-11-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-bromoorotate To be Published
5V23	SeMet crystal structure of the Neisseria meningitidis non-core minor pilin PilV in the orthorhombic form Descriptor: GLYCEROL, Type IV pilin protein Authors: Kolappan, S, Craig, L. Deposit date: 2017-03-02 Release date: 2018-02-07 Last modified: 2020-01-08 Method: X-RAY DIFFRACTION (1.956 Å) Cite: SeMet structure of the non-core minor pilin PilV from Neisseria meningitidis in the orthorhombic form To Be Published
4V8M	High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome Descriptor: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... Authors: Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. Deposit date: 2012-12-09 Release date: 2014-07-09 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (5.57 Å) Cite: High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
4JD4	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-065 Descriptor: 5-{2-[2-(hydroxymethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-02-23 Release date: 2014-02-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-065 To be Published
3W1X	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-121 Descriptor: 5-{2-[4-(cyanomethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-22 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-121. To be Published
4JDB	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-005 Descriptor: 5-[2-(7-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-02-24 Release date: 2014-02-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-005 To be Published
3W2M	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-183 Descriptor: 2,6-dioxo-5-{2-[4-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-30 Release date: 2013-12-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-183. To be Published
3W1L	Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate Descriptor: 5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-16 Release date: 2013-11-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate TO BE PUBLISHED
3W1A	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate derivatives Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-13 Release date: 2013-11-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate derivatives To be Published
3W23	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-131 Descriptor: 5-[2-(3-chlorophenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-26 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-131 To be Published
3W1T	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-095 Descriptor: 2,6-dioxo-5-{2-[3-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-21 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-095 To be Published
3W22	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-125 Descriptor: 5-[2-(4-tert-butylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-26 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-125 To be Published
3W1U	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-111 Descriptor: 5-[2-(4-methylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-21 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-111 To be Published
3W2K	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165 Descriptor: 5-[2-(4-fluoro-3-methylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-11-29 Release date: 2013-12-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165 To be Published
3W2U	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-193 Descriptor: 5-{2-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2012-12-05 Release date: 2013-12-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-193 To be Published
3W7Q	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-5-127 Descriptor: 5-{2-[1-(tert-butoxycarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-03-02 Release date: 2014-03-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-5-127 To be Published
3W85	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-3-139 Descriptor: 5-{2-[3-(methoxycarbonyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-03-12 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-3-139 To be Published
3W72	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-107 Descriptor: 5-[2-(naphthalen-1-yl)ethyl]-2,6-dioxo-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-02-27 Release date: 2014-03-05 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-107 To be Published
3W7D	Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-170 Descriptor: 5-[2-(8-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-02-28 Release date: 2014-03-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-170 To be Published

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