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8H1L
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BU of 8h1l by Molmil
Crystal structure of glucose-2-epimerase in complex with D-Glucitol from Runella slithyformis Runsl_4512
Descriptor: N-acylglucosamine 2-epimerase, sorbitol
Authors:Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M.
Deposit date:2022-10-03
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
4UXY
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BU of 4uxy by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
2RTC
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BU of 2rtc by Molmil
APOSTREPTAVIDIN, PH 3.60, SPACE GROUP I222
Descriptor: STREPTAVIDIN, SULFATE ION
Authors:Katz, B.A.
Deposit date:1997-09-11
Release date:1998-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
8HBW
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BU of 8hbw by Molmil
Structure of human UCP1 in the ATP-bound state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ...
Authors:Chen, L, Kang, Y.
Deposit date:2022-10-31
Release date:2023-06-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural basis for the binding of DNP and purine nucleotides onto UCP1.
Nature, 620, 2023
8HIV
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BU of 8hiv by Molmil
The structure of apo-SoBcmB with Fe(II) and AKG
Descriptor: 2-OXOGLUTARIC ACID, FE (II) ION, Fe/2OG dependent dioxygenase
Authors:Wu, L, Zhou, J.H.
Deposit date:2022-11-22
Release date:2023-07-05
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.2000308 Å)
Cite:Enzymatic catalysis favours eight-membered over five-membered ring closure in bicyclomycin biosynthesis
Nat Catal, 6, 2023
4UYN
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BU of 4uyn by Molmil
SAR156497 an exquisitely selective inhibitor of Aurora kinases
Descriptor: AURORA KINASE A, ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate
Authors:Carry, J.C, Clerc, F, Minoux, H, Schio, L, Mauger, J, Nair, A, Parmantier, E, Lemoigne, R, Delorme, C, Nicolas, J.P, Krick, A, Abecassis, P.Y, Crocq-Stuerga, V, Pouzieux, S, Delarbre, L, Maignan, S, Bertrand, T, Bjergarde, K, Ma, N, Lachaud, S, Guizani, H, Lebel, R, Doerflinger, G, Monget, S, Perron, S, Gasse, F, Angouillant-Boniface, O, Filoche-Romme, B, Murer, M, Gontier, S, Prevost, C, Monteiro, M.L, Combeau, C.
Deposit date:2014-09-02
Release date:2014-11-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sar156497, an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
2RQS
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BU of 2rqs by Molmil
3D structure of Pin from the psychrophilic archeon Cenarcheaum symbiosum (CsPin)
Descriptor: Parvulin-like peptidyl-prolyl isomerase
Authors:Zhukov, I, Jaremko, L, Jaremko, M, Mueller, J.W, Bayer, P.
Deposit date:2009-11-17
Release date:2010-11-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl Isomerases
J.Biol.Chem., 286, 2011
8HL9
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BU of 8hl9 by Molmil
Crystal structure of Galectin-8 C-CRD with part of linker
Descriptor: Galectin-8
Authors:Si, Y.L.
Deposit date:2022-11-29
Release date:2023-07-05
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Linker remodels human Galectin-8 structure and regulates its hemagglutination and pro-apoptotic activity.
Int.J.Biol.Macromol., 245, 2023
4UYS
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BU of 4uys by Molmil
X-ray structure of the N-terminal domain of the flocculin Flo11 from Saccharomyces cerevisiae
Descriptor: FLOCCULATION PROTEIN FLO11, MAGNESIUM ION, SODIUM ION
Authors:Kraushaar, T, Veelders, M, Brueckner, S, Rhinow, D, Moesch, H.U, Essen, L.O.
Deposit date:2014-09-03
Release date:2015-08-12
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Interactions by the Fungal Flo11 Adhesin Depend on a Fibronectin Type III-Like Adhesin Domain Girdled by Aromatic Bands.
Structure, 23, 2015
2RH2
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BU of 2rh2 by Molmil
High Resolution DHFR R-67
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2
Authors:Krahn, J.M, London, R.E.
Deposit date:2007-10-05
Release date:2008-06-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:Crystal Structure of a Type II Dihydrofolate Reductase Catalytic Ternary Complex
Biochemistry, 46, 2007
8HKB
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BU of 8hkb by Molmil
TPA bound-form of Periplasmic terephthalate binding protein (TBP) from Ideonella sakaiensis mutant K184D
Descriptor: Periplasmic terephthalate binding protein (TBP), terephthalic acid
Authors:Lee, S.H, Seo, H, Kim, K.-J.
Deposit date:2022-11-25
Release date:2023-06-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular mechanism underlying high-affinity terephthalate binding and conformational change of TBP from Ideonella sakaiensis.
Int.J.Biol.Macromol., 243, 2023
4UZ8
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BU of 4uz8 by Molmil
The SeMet structure of the family 46 carbohydrate-binding module (CBM46) of endo-beta-1,4-glucanase B (Cel5B) from Bacillus halodurans
Descriptor: ENDO-BETA-1,4-GLUCANASE (CELULASE B), SULFATE ION
Authors:Venditto, I, Santos, H, Ferreira, L.M.A, Sakka, K, Fontes, C.M.G.A, Najmudin, S.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Family 46 Carbohydrate-Binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and Beta-1,3-1,4-Glucans Through Distinct Mechanisms.
J.Biol.Chem., 290, 2015
8HN3
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BU of 8hn3 by Molmil
Soluble domain of cytochrome c-556 from Chlorobaculum tepidum
Descriptor: ACETATE ION, Cytochrome c-556, GLYCEROL, ...
Authors:Kishimoto, H, Azai, C, Yamamoto, T, Mutoh, R, Nakaniwa, T, Tanaka, H, Kurisu, G, Oh-oka, H.
Deposit date:2022-12-07
Release date:2023-07-05
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Soluble domains of cytochrome c-556 and Rieske iron-sulfur protein from Chlorobaculum tepidum: Crystal structures and interaction analysis.
Curr Res Struct Biol, 5, 2023
4UZQ
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BU of 4uzq by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, PALMITOLEIC ACID, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-07
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
2RHF
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BU of 2rhf by Molmil
D. radiodurans RecQ HRDC domain 3
Descriptor: DNA helicase RecQ, PHOSPHATE ION
Authors:Keck, J.L, Killoran, M.P.
Deposit date:2007-10-09
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ.
Nucleic Acids Res., 36, 2008
4W7R
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BU of 4w7r by Molmil
Crystal Structure of Full-Length Split GFP Mutant E124H/K126H Copper Mediated Dimer, P 21 Space Group
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, fluorescent protein E124H/K126C
Authors:Leibly, D.J, Waldo, G.S, Yeates, T.O.
Deposit date:2014-08-22
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
8HKA
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BU of 8hka by Molmil
TPA bound-form of Periplasmic terephthalate binding protein (TBP) from Ideonella sakaiensis
Descriptor: Periplasmic terephthalate binding protein (TBP), terephthalic acid
Authors:Lee, S.H, Seo, H, Kim, K.-J.
Deposit date:2022-11-25
Release date:2023-06-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Molecular mechanism underlying high-affinity terephthalate binding and conformational change of TBP from Ideonella sakaiensis.
Int.J.Biol.Macromol., 243, 2023
4W81
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BU of 4w81 by Molmil
Periplasmically Produced Monomeric Single Domain Antibody (sdAb) C22A/C99V variant against Staphylococcal enterotoxin B (SEB) at pH 8.0
Descriptor: SULFATE ION, Single Domain Antibody
Authors:George, J, Legler, P.M.
Deposit date:2014-08-22
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
8HP5
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BU of 8hp5 by Molmil
Crystal structure of (S)-2-haloacid dehalogenase
Descriptor: (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL
Authors:Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J.
Deposit date:2022-12-12
Release date:2023-06-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening
Catalysis Science And Technology, 2023
2RV3
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BU of 2rv3 by Molmil
Solution structures of the DNA-binding domain (ZF15) of immune-related zinc-finger protein ZFAT
Descriptor: ZINC ION, Zinc finger protein ZFAT
Authors:Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S.
Deposit date:2015-01-26
Release date:2015-04-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
4W88
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BU of 4w88 by Molmil
Crystal structure of XEG5A, a GH5 xyloglucan-specific endo-beta-1,4-glucanase from ruminal metagenomic library, in complex with a xyloglucan oligosaccharide and TRIS
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Xyloglucan-specific endo-beta-1,4-glucanase, ...
Authors:Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
Deposit date:2014-08-22
Release date:2015-03-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
8HL6
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BU of 8hl6 by Molmil
Crystal structure of human valosin-containing protein methyltransferase
Descriptor: Protein N-lysine methyltransferase METTL21D, S-ADENOSYLMETHIONINE
Authors:Kang, W, Yang, J.K.
Deposit date:2022-11-29
Release date:2023-07-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase.
Iscience, 26, 2023
2RVE
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BU of 2rve by Molmil
THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA SEGMENTS
Descriptor: DNA (5'-D(*CP*GP*AP*GP*CP*TP*CP*G)-3'), PROTEIN (ECO RV (E.C.3.1.21.4))
Authors:Winkler, F.K, Banner, D.W, Oefner, C, Tsernoglou, D, Brown, R.S, Heathman, S.P, Bryan, R.K, Martin, P.D, Petratos, K, Wilson, K.S.
Deposit date:1991-03-19
Release date:1992-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.
EMBO J., 12, 1993
4W8O
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BU of 4w8o by Molmil
Structure of the luciferase-like enzyme from the nonluminescent Zophobas morio mealworm
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, luciferase-like enzymeAMP-CoA-ligase
Authors:Santos, C.R, Prado, R.A, Viviani, V, Murakami, M.T.
Deposit date:2014-08-25
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the luciferase-like enzyme from the nonluminescent Zophobas morio mealworm
To Be Published
2RHZ
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BU of 2rhz by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with D355N point mutation
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007

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