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8B6L
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BU of 8b6l by Molmil
Subtomogram average of the human Sec61-TRAP-OSTA-translocon
Descriptor: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ...
Authors:Gemmer, M, Fedry, J.M.M, Forster, F.G.
Deposit date:2022-09-27
Release date:2022-12-07
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Visualization of translation and protein biogenesis at the ER membrane.
Nature, 614, 2023
7ZL3
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BU of 7zl3 by Molmil
Signal peptide mimicry primes Sec61 for client-selective inhibition
Descriptor: Cyclic depsipeptide signal peptide mimic, Protein transport protein Sec61 subunit alpha, Protein transport protein Sec61 subunit beta, ...
Authors:Rehan, S, Paavilainen O, V.
Deposit date:2022-04-13
Release date:2023-03-22
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Signal peptide mimicry primes Sec61 for client-selective inhibition.
Nat.Chem.Biol., 19, 2023
6FTI
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BU of 6fti by Molmil
Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome
Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Braunger, K, Becker, T, Beckmann, R.
Deposit date:2018-02-22
Release date:2018-03-21
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
6W6L
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BU of 6w6l by Molmil
Cryo-EM structure of the human ribosome-TMCO1 translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Keenan, R.J, McGilvray, P.T.
Deposit date:2020-03-17
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:An ER translocon for multi-pass membrane protein biogenesis.
Elife, 9, 2020
5J88
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BU of 5j88 by Molmil
Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-07
Release date:2016-07-06
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5OT7
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BU of 5ot7 by Molmil
Elongation factor G-ribosome complex captures in the absence of inhibitors.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mace, K, Giudice, E, Chat, S, Gillet, R.
Deposit date:2017-08-21
Release date:2018-02-14
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
5J3C
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BU of 5j3c by Molmil
Thermus thermophilus 70S termination complex containing E. coli RF1
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2016-03-30
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
3CCQ
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BU of 3ccq by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-26
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CD6
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BU of 3cd6 by Molmil
Co-cystal of large Ribosomal Subunit mutant G2616A with CC-Puromycin
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-26
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
5AN9
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BU of 5an9 by Molmil
Mechanism of eIF6 release from the nascent 60S ribosomal subunit
Descriptor: 26S RIBOSOMAL RNA, 60S ACIDIC RIBOSOMAL PROTEIN P0, 60S RIBOSOMAL PROTEIN L10, ...
Authors:Weis, F, Giudice, E, Churcher, M, Jin, L, Hilcenko, C, Wong, C.C, Traynor, D, Kay, R.R, Warren, A.J.
Deposit date:2015-09-06
Release date:2015-10-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 22, 2015
5APN
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BU of 5apn by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
5GAE
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BU of 5gae by Molmil
RNC in complex with a translocating SecYEG
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
Deposit date:2015-11-25
Release date:2016-01-27
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
9BDP
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BU of 9bdp by Molmil
80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2024-04-12
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of angiogenin activation by the ribosome.
Nature, 630, 2024
8Y39
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BU of 8y39 by Molmil
cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
Deposit date:2024-01-28
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
9BDL
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BU of 9bdl by Molmil
80S ribosome with angiogenin
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2024-04-12
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural mechanism of angiogenin activation by the ribosome.
Nature, 630, 2024
9FBV
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BU of 9fbv by Molmil
70S Escherichia coli ribosome with P-site initiatior tRNA.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
Authors:Koller, T.O, Wilson, D.N.
Deposit date:2024-05-14
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
5XTI
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BU of 5xti by Molmil
Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
Authors:Gu, J, Wu, M, Yang, M.
Deposit date:2017-06-19
Release date:2017-09-13
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (17.4 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5X8P
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BU of 5x8p by Molmil
Structure of the 70S chloroplast ribosome from spinach
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Ahmed, T, Shi, J, Bhushan, S.
Deposit date:2017-03-03
Release date:2017-06-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
5XTB
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BU of 5xtb by Molmil
Cryo-EM structure of human respiratory complex I matrix arm
Descriptor: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Gu, J, Wu, M, Yang, M.
Deposit date:2017-06-18
Release date:2017-08-30
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5X8T
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BU of 5x8t by Molmil
Structure of the 50S large subunit of chloroplast ribosome from spinach
Descriptor: 23S rRNA, 4.8S rRNA, 50S ribosomal protein L13, ...
Authors:Ahmed, T, Shi, J, Bhushan, S.
Deposit date:2017-03-03
Release date:2017-06-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
6FKR
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BU of 6fkr by Molmil
Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome
Descriptor: 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N.
Deposit date:2018-01-24
Release date:2018-03-28
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.
Cell Chem Biol, 25, 2018
5XTD
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BU of 5xtd by Molmil
Cryo-EM structure of human respiratory complex I
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
Authors:Gu, J, Wu, M, Yang, M.
Deposit date:2017-06-19
Release date:2017-08-30
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
6G2J
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BU of 6g2j by Molmil
Mouse mitochondrial complex I in the active state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J.
Deposit date:2018-03-23
Release date:2018-06-06
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol., 25, 2018
6GBZ
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BU of 6gbz by Molmil
50S ribosomal subunit assembly intermediate state 5
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
4V63
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BU of 4v63 by Molmil
Structural basis for translation termination on the 70S ribosome.
Descriptor: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
Authors:Laurberg, M, Asahara, H, Korostelev, A, Zhu, J, Trakhanov, S, Noller, H.F.
Deposit date:2008-05-16
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.207 Å)
Cite:Structural basis for translation termination on the 70S ribosome
Nature, 454, 2008

223532

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