5GT9
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![BU of 5gt9 by Molmil](/molmil-images/mine/5gt9) | The X-ray structure of 7beta-hydroxysteroid dehydrogenase | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein | Authors: | Wang, F, Wang, R, Lv, Z, Chen, Q, Huo, X. | Deposit date: | 2016-08-19 | Release date: | 2017-05-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes Acta Crystallogr F Struct Biol Commun, 73, 2017
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8J2A
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![BU of 8j2a by Molmil](/molmil-images/mine/8j2a) | |
1GEG
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![BU of 1geg by Molmil](/molmil-images/mine/1geg) | CRYATAL STRUCTURE ANALYSIS OF MESO-2,3-BUTANEDIOL DEHYDROGENASE | Descriptor: | ACETOIN REDUCTASE, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | Authors: | Otagiri, M, Kurisu, G, Ui, S, Kusunoki, M. | Deposit date: | 2000-11-10 | Release date: | 2001-02-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms. J.Biochem., 129, 2001
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8J2C
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![BU of 8j2c by Molmil](/molmil-images/mine/8j2c) | |
2BD0
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![BU of 2bd0 by Molmil](/molmil-images/mine/2bd0) | Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin | Descriptor: | BIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, sepiapterin reductase | Authors: | Supangat, S, Seo, K.H, Choi, Y.K, Park, Y.S, Lee, K.H. | Deposit date: | 2005-10-19 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of Chlorobium tepidum sepiapterin reductase complex reveals the novel substrate binding mode for stereospecific production of L-threo-tetrahydrobiopterin J.Biol.Chem., 281, 2006
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5Z2L
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![BU of 5z2l by Molmil](/molmil-images/mine/5z2l) | Crystal structure of BdcA in complex with NADPH | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Cyclic-di-GMP-binding biofilm dispersal mediator protein, ... | Authors: | Yang, W.S, Hou, Y.J, Li, D.F, Wang, D.C. | Deposit date: | 2018-01-03 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A potential substrate binding pocket of BdcA plays a critical role in NADPH recognition and biofilm dispersal Biochem. Biophys. Res. Commun., 497, 2018
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5VML
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![BU of 5vml by Molmil](/molmil-images/mine/5vml) | |
3G1T
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![BU of 3g1t by Molmil](/molmil-images/mine/3g1t) | CRYSTAL STRUCTURE OF short chain dehydrogenase from Salmonella enterica subsp. enterica serovar Typhi str. CT18 | Descriptor: | MAGNESIUM ION, short chain dehydrogenase | Authors: | Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-01-30 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CRYSTAL STRUCTURE OF short chain dehydrogenase from Salmonella enterica subsp. enterica
serovar Typhi str. CT18 To be Published
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5WQP
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![BU of 5wqp by Molmil](/molmil-images/mine/5wqp) | Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition II) | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, PHOSPHATE ION, ... | Authors: | Li, S, Wang, Y, Bartlam, M. | Deposit date: | 2016-11-27 | Release date: | 2017-10-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
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1E6W
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![BU of 1e6w by Molmil](/molmil-images/mine/1e6w) | |
5LCX
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![BU of 5lcx by Molmil](/molmil-images/mine/5lcx) | Isopiperitenone reductase from Mentha piperita in complex with NADP | Descriptor: | (-)-isopiperitenone reductase, (4S)-2-METHYL-2,4-PENTANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | Deposit date: | 2016-06-22 | Release date: | 2016-08-31 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.709 Å) | Cite: | Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
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6I6C
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![BU of 6i6c by Molmil](/molmil-images/mine/6i6c) | SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 2 | Descriptor: | (1~{R},2~{S},4~{S})-~{N}-(3-chloranyl-4-cyano-phenyl)sulfonylbicyclo[2.2.1]heptane-2-carboxamide, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Alen, J, Schade, M, Wagener, M, Blaesse, M. | Deposit date: | 2018-11-15 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62, 2019
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1SNY
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![BU of 1sny by Molmil](/molmil-images/mine/1sny) | Carbonyl reductase Sniffer of D. melanogaster | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, sniffer CG10964-PA | Authors: | Sgraja, T, Ulschmid, J, Becker, K, Schneuwly, S, Klebe, G, Reuter, K, Heine, A. | Deposit date: | 2004-03-12 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Insights into the Neuroprotective-acting Carbonyl Reductase Sniffer of Drosophila melanogaster. J.Mol.Biol., 342, 2004
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8AEO
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![BU of 8aeo by Molmil](/molmil-images/mine/8aeo) | |
3F5Q
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![BU of 3f5q by Molmil](/molmil-images/mine/3f5q) | CRYSTAL STRUCTURE OF putative short chain dehydrogenase from Escherichia coli CFT073 | Descriptor: | dehydrogenase | Authors: | Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-11-04 | Release date: | 2009-01-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of an uncharacterized protein to be published
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6YC8
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![BU of 6yc8 by Molmil](/molmil-images/mine/6yc8) | Crystal structure of KRED1-Pglu enzyme | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... | Authors: | Di Pisa, F. | Deposit date: | 2020-03-18 | Release date: | 2021-02-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction. Bioorg.Chem., 108, 2021
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8AER
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![BU of 8aer by Molmil](/molmil-images/mine/8aer) | |
3BHJ
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![BU of 3bhj by Molmil](/molmil-images/mine/3bhj) | Crystal structure of human Carbonyl Reductase 1 in complex with glutathione | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, Carbonyl reductase [NADPH] 1, ... | Authors: | Rauh, D, Bateman, R.L, Shokat, K.M. | Deposit date: | 2007-11-28 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Human carbonyl reductase 1 is an s-nitrosoglutathione reductase J.Biol.Chem., 283, 2008
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5WQO
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![BU of 5wqo by Molmil](/molmil-images/mine/5wqo) | Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition I) | Descriptor: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable dehydrogenase, ... | Authors: | Li, S, Wang, Y, Bartlam, M. | Deposit date: | 2016-11-27 | Release date: | 2017-10-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
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6I6T
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![BU of 6i6t by Molmil](/molmil-images/mine/6i6t) | SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 5 | Descriptor: | 1,2-ETHANEDIOL, 4-bromanyl-1-oxidanyl-naphthalene-2-carboxylic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Alen, J, Schade, M, Wagener, M, Blaesse, M. | Deposit date: | 2018-11-15 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62, 2019
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3VZP
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![BU of 3vzp by Molmil](/molmil-images/mine/3vzp) | Crystal structure of PhaB from Ralstonia eutropha | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Acetoacetyl-CoA reductase, GLYCEROL, ... | Authors: | Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. | Deposit date: | 2012-10-15 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics Appl.Environ.Microbiol., 79, 2013
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4YA6
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![BU of 4ya6 by Molmil](/molmil-images/mine/4ya6) | Crystal structure of LigO-apo form from Sphingobium sp. strain SYK-6 | Descriptor: | C alpha-dehydrogenase | Authors: | Pereira, J.H, McAndrew, R.P, Heins, R.A, Sale, K.L, Simmons, B.A, Adams, P.D. | Deposit date: | 2015-02-17 | Release date: | 2016-03-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin beta-Aryl Ether Cleavage Pathway from Sphingobium sp. SYK-6. J.Biol.Chem., 291, 2016
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1FMC
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![BU of 1fmc by Molmil](/molmil-images/mine/1fmc) | 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, GLYCOCHENODEOXYCHOLIC ACID | Authors: | Tanaka, N, Nonaka, T, Mitsui, Y. | Deposit date: | 1996-04-26 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry, 35, 1996
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1CYD
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![BU of 1cyd by Molmil](/molmil-images/mine/1cyd) | CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL | Descriptor: | CARBONYL REDUCTASE, ISOPROPYL ALCOHOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Tanaka, N, Nonaka, T, Mitsui, Y. | Deposit date: | 1995-09-01 | Release date: | 1996-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure, 4, 1996
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8DT1
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![BU of 8dt1 by Molmil](/molmil-images/mine/8dt1) | |